PMID- 37150618
OWN - NLM
STAT- MEDLINE
DCOM- 20230509
LR  - 20230519
IS  - 1347-4715 (Electronic)
IS  - 1342-078X (Print)
IS  - 1342-078X (Linking)
VI  - 28
DP  - 2023
TI  - Chlorinated persistent organic pollutants in human breast milk in the Miyagi 
      Prefecture disaster-affected area 1 year after the Great East Japan Earthquake of 
      2011.
PG  - 27
LID - 10.1265/ehpm.22-00260 [doi]
LID - 27
AB  - BACKGROUND: In the Great East Japan Earthquake of 11 March 2011, an earthquake 
      and accompanying tsunami struck the Tohoku region of northeastern Japan. 
      Buildings collapsed and the tsunami spread waste, including hazardous materials. 
      This study aimed to determine the concentrations of persistent organic pollutants 
      (POPs) in the breast milk of mothers living in the disaster-affected area of 
      Sendai 1 year after the earthquake. Temporal trends in the POPs concentrations 
      were evaluated by comparison with previous studies. METHODS: One hundred breast 
      milk samples were obtained from lactating mothers at a hospital in Sendai in 
      2012. The results were compared with those from other years to examine whether 
      there were changes in the POPs concentrations after the earthquake. We measured 
      polychlorinated biphenyls (PCBs) and organochlorine pesticides, such as 
      chlordanes, using gas chromatography-mass spectrometer (GC-MS) with negative 
      chemical ionization, and dichlorodiphenyl trichloroethane (DDT) and its 
      metabolites using GC-MS with electron impact ionization. RESULTS: The mean total 
      PCBs (11 congeners), total chlordane, and total DDT concentrations were 76.2 ng/g 
      lipid, 39.8 ng/g lipid, and 73.5 ng/g lipid, respectively. For the samples 
      collected in 2012, the concentrations of POPs in breast milk showed minimal 
      changes compared with results from previous years for samples collected at the 
      same hospital in Sendai. CONCLUSIONS: Our study demonstrates that 1 year after 
      the earthquake and tsunami, the concentrations of chlorinated POPs in breast milk 
      had not changed substantially.
FAU - Choi, Jungmi
AU  - Choi J
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
AD  - Department of Research Promotion and Management, National Cerebral and 
      Cardiovascular Center Research Institute.
FAU - Fujii, Yukiko
AU  - Fujii Y
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
AD  - Department of Pharmaceutical Sciences, Daiichi University of Pharmacy.
FAU - Lyu, Zhaoqing
AU  - Lyu Z
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
FAU - Kobayashi, Hatasu
AU  - Kobayashi H
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
AD  - Department of Environmental and Molecular Medicine, Mie University Graduate 
      School of Medicine.
FAU - Fujitani, Tomoko
AU  - Fujitani T
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
FAU - Harada, Kouji H
AU  - Harada KH
AUID- ORCID: 0000-0001-7319-123X
AD  - Department of Health and Environmental Science, Kyoto University Graduate School 
      of Medicine.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Environ Health Prev Med
JT  - Environmental health and preventive medicine
JID - 9609642
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - 0 (Persistent Organic Pollutants)
RN  - CIW5S16655 (DDT)
RN  - 0 (Environmental Pollutants)
RN  - 12789-03-6 (Chlordan)
RN  - 0 (Lipids)
SB  - IM
MH  - Female
MH  - Humans
MH  - *Polychlorinated Biphenyls
MH  - *Earthquakes
MH  - Persistent Organic Pollutants
MH  - DDT/analysis
MH  - Milk, Human/chemistry/metabolism
MH  - Japan
MH  - Lactation
MH  - *Disasters
MH  - *Environmental Pollutants/analysis
MH  - Chlordan/analysis
MH  - Lipids
PMC - PMC10188281
OTO - NOTNLM
OT  - Breast milk
OT  - Great East Japan Earthquake
OT  - Japan
OT  - Natural disaster
OT  - Persistent organic pollutant
COIS- The authors declare that they have no competing interests.
EDAT- 2023/05/08 00:41
MHDA- 2023/05/09 06:42
PMCR- 2023/05/02
CRDT- 2023/05/07 21:53
PHST- 2023/05/09 06:42 [medline]
PHST- 2023/05/08 00:41 [pubmed]
PHST- 2023/05/07 21:53 [entrez]
PHST- 2023/05/02 00:00 [pmc-release]
AID - 22-00260 [pii]
AID - 10.1265/ehpm.22-00260 [doi]
PST - ppublish
SO  - Environ Health Prev Med. 2023;28:27. doi: 10.1265/ehpm.22-00260.