PMID- 37153466 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230509 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 10 DP - 2023 TI - Blood pressure and renal outcomes after renal artery aneurysm intervention: Single-center experience and review of literature. PG - 1127154 LID - 10.3389/fcvm.2023.1127154 [doi] LID - 1127154 AB - OBJECTIVE: To explore the results of hypertension improvement and renal function preservation after renal artery aneurysm (RAA) repair. METHODS: This study retrospectively analyzed the change in blood pressure (BP) and renal outcomes of 59 RAA patients throughout either open or endovascular operations and follow-up at a large center. Patients were grouped according to the difference in their BP at the last follow-up vs. their baseline value. Logistic regression was conducted to explore risk factors for perioperative BP relief and long-term hypertension reonset. Previous studies of RAA with records of BP, blood creatinine level, or GFR/eGFR results are reviewed. RESULTS: Hypertension was observed in 62.7% (37/59) of the patients included. Postoperative BP declined from 132.20 +/- 16.46/79.92 +/- 9.64 mmHg to 122.41 +/- 11.17/71.10 +/- 9.82 mmHg, while eGFR changed from 108.17 +/- 24.73 to 98.92 +/- 23.87 ml/min/1.73 m(2). The median follow-up was 854 [IQR: 1,405] days. Both open and endovascular techniques significantly relieved hypertension and did not impair renal function much. Lower preoperative systolic BP (SBP) was significantly associated with hypertension relief (OR = 0.83, 95% CI: 0.70-0.99). Among patients with normal BP after the operation, higher postoperative SBP was significantly associated with new-onset hypertension (OR = 1.14, 95% CI: 1.01-1.29). Literature review indicated that renal function usually remained normal at follow-up, whereas relief of hypertension varied. CONCLUSION: Patients with lower preoperative SBP were likely to benefit more from the operation, while higher postoperative SBP indicated a higher chance of hypertension reonset. Creatinine level and eGFR generally remained stable regardless of operation type. CI - (c) 2023 Li, Li, Liu, Zeng, Ye, Shao and Zheng. FAU - Li, Siting AU - Li S AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Li, Fangda AU - Li F AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Liu, Zhili AU - Liu Z AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Zeng, Rong AU - Zeng R AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Ye, Wei AU - Ye W AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Shao, Jiang AU - Shao J AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. FAU - Zheng, Yuehong AU - Zheng Y AD - Department of Vascular Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. AD - Department of State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China. LA - eng PT - Journal Article DEP - 20230421 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 PMC - PMC10160466 OTO - NOTNLM OT - blood pressure OT - endovascular repair OT - open surgery OT - renal artery aneurysm OT - renal outcome COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2023/05/08 06:41 MHDA- 2023/05/08 06:42 PMCR- 2023/01/01 CRDT- 2023/05/08 04:15 PHST- 2022/12/19 00:00 [received] PHST- 2023/03/31 00:00 [accepted] PHST- 2023/05/08 06:42 [medline] PHST- 2023/05/08 06:41 [pubmed] PHST- 2023/05/08 04:15 [entrez] PHST- 2023/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2023.1127154 [doi] PST - epublish SO - Front Cardiovasc Med. 2023 Apr 21;10:1127154. doi: 10.3389/fcvm.2023.1127154. eCollection 2023.