PMID- 37155616 OWN - NLM STAT- MEDLINE DCOM- 20230810 LR - 20230810 IS - 1557-9034 (Electronic) IS - 1092-6429 (Linking) VI - 33 IP - 8 DP - 2023 Aug TI - Comparison of Laparoscopic Sleeve Gastrectomy and Single Anastomosis Sleeve Ileal Bypass in Type 2 Diabetes Mellitus Remission Using International Criteria. PG - 768-775 LID - 10.1089/lap.2023.0112 [doi] AB - Introduction: Single anastomosis sleeve ileal (SASI) bypass procedure is recommended in the treatment of patients with obesity, who have comorbidities such as type 2 diabetes mellitus (T2DM). Meanwhile, laparoscopic sleeve gastrectomy (LSG) has become the most preferred contemporary bariatric procedure. Research comparing these two techniques are scarce in the literature. In this study, we aimed to compare LSG and SASI procedures in terms of weight loss and diabetes remission. Materials and Methods: Thirty patients, who underwent LSG and 31 patients, who underwent SASI, with a body mass index (BMI) of 35 and above, and under unsuccessful medical treatment, in terms of T2DM, were included in the study. Patients' demographic data were recorded. Oral antidiabetic drugs and insulin use, HbA1c and fasting blood glucose values, and BMI values were recorded preoperatively, at thd sixth month and at first year. According to these data, patients were compared in terms of primarily diabetes remission and secondarily weight loss. Results: At the sixth month and first year, the mean excess weight loss (EWL) values of the SASI group were 55.2% +/- 12.45% and 71.67% +/- 15.75%, respectively, while EWL values of the LSG group were 57.41% +/- 16.22% and 69.73% +/- 16.65%, respectively (P > .05). T2DM evaluations revealed that in the SASI group, 25 (80.65%) patients at the sixth month and 26 (83.87%) patients at the first year had either clinical improvement or remission, whereas 23 (76.67%) patients at the sixth month and 26 (86,67%) patients at the first year in the LSG group had the same outcomes (P > .05). Conclusion: The short-term comparison of LSG and SASI procedures revealed similar results in terms of weight loss and T2DM remission. Hence, LSG can be considered as the first-step treatment of morbid obesity accompanied by T2DM, since it is a simpler surgical procedure. FAU - Yildirak, Muhammed Kadir AU - Yildirak MK AUID- ORCID: 0000-0002-6241-5661 AD - Department of General Surgery, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. FAU - Sisik, Abdullah AU - Sisik A AUID- ORCID: 0000-0002-7500-8651 AD - Department of General Surgery, Dr. HE Obesity Clinic, Istanbul, Turkey. FAU - Demirpolat, Muhammed Taha AU - Demirpolat MT AUID- ORCID: 0000-0002-3772-610X AD - Department of General Surgery, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, Turkey. LA - eng PT - Journal Article DEP - 20230508 PL - United States TA - J Laparoendosc Adv Surg Tech A JT - Journal of laparoendoscopic & advanced surgical techniques. Part A JID - 9706293 SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2/complications/surgery MH - Treatment Outcome MH - *Laparoscopy/methods MH - *Obesity, Morbid/surgery/complications MH - Anastomosis, Surgical MH - Gastrectomy/methods MH - Weight Loss MH - *Gastric Bypass/methods MH - Retrospective Studies OTO - NOTNLM OT - laparoscopic sleeve gastrectomy OT - single anastomosis sleeve ileal bypass OT - type 2 diabetes mellitus EDAT- 2023/05/08 18:42 MHDA- 2023/08/10 06:43 CRDT- 2023/05/08 14:13 PHST- 2023/08/10 06:43 [medline] PHST- 2023/05/08 18:42 [pubmed] PHST- 2023/05/08 14:13 [entrez] AID - 10.1089/lap.2023.0112 [doi] PST - ppublish SO - J Laparoendosc Adv Surg Tech A. 2023 Aug;33(8):768-775. doi: 10.1089/lap.2023.0112. Epub 2023 May 8.