PMID- 37155964
OWN - NLM
STAT- MEDLINE
DCOM- 20230908
LR  - 20230908
IS  - 1538-943X (Electronic)
IS  - 1058-2916 (Linking)
VI  - 69
IP  - 9
DP  - 2023 Sep 1
TI  - Evaluation of Vasoactive-Inotropic Score and Survival to Decannulation in Adult 
      Patients on Venoarterial Extracorporeal Life Support: An Observational Cohort 
      Study.
PG  - 873-878
LID - 10.1097/MAT.0000000000001982 [doi]
AB  - Extracorporeal life support with venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) is used to assist circulation in patients with severe cardiogenic shock 
      or cardiac arrest. The vasoactive-inotropic score (VIS) is a standardized 
      calculation of vasoactive medication support which uses coefficients for each 
      medication that converts them to an equivalent value. The purpose of this study 
      was to assess the VIS as an early prognostication tool for survival to 
      decannulation patients on adult VA-ECMO support. This was a single-center, 
      observational cohort study of adult patients who received VA-ECMO support 
      compared based on their survival to decannulation. The primary endpoint was the 
      VIS at hour 24 postcannulation. Among the 265 patients included in this study, 
      140 patients (52.8%) survived to decannulation of VA-ECMO. At 24 hours 
      postcannulation, a lower VIS was observed in the group that survived 
      decannulation (6.5 +/- 7.5 vs. 12.3 +/- 16.9; p < 0.001). Multivariate analysis 
      performed also demonstrates an association between 24-hour VIS and survival to 
      decannulation (odds ratio 0.95; 95% confidence interval, 0.91-0.95). This study 
      suggests that the 24-hour VIS may be an early prognostic indicator in patients on 
      VA-ECMO patients. http://links.lww.com/ASAIO/B39.
CI  - Copyright (c) ASAIO 2023.
FAU - Dunton, Kelly
AU  - Dunton K
AUID- ORCID: 0000-0003-1297-6062
AD  - From the Department of Pharmacy, Memorial Hermann-Texas Medical Center, Houston, 
      Texas.
AD  - Department of Pharmacy, AdventHealth, Orlando, Florida.
FAU - Weeks, Phillip A
AU  - Weeks PA
AD  - From the Department of Pharmacy, Memorial Hermann-Texas Medical Center, Houston, 
      Texas.
FAU - Gulbis, Brian
AU  - Gulbis B
AD  - From the Department of Pharmacy, Memorial Hermann-Texas Medical Center, Houston, 
      Texas.
FAU - Jumean, Marwan
AU  - Jumean M
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Kumar, Sachin
AU  - Kumar S
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Janowiak, Lisa
AU  - Janowiak L
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Banjac, Igor
AU  - Banjac I
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Radovancevic, Rajko
AU  - Radovancevic R
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Gregoric, Igor
AU  - Gregoric I
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
FAU - Kar, Biswajit
AU  - Kar B
AD  - Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for 
      Advanced Heart Failure, University of Texas Health Science Center at Houston, 
      Houston, Texas.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20230508
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
SB  - IM
MH  - Adult
MH  - Humans
MH  - Cohort Studies
MH  - *Extracorporeal Membrane Oxygenation
MH  - *Heart Arrest/therapy
MH  - Prognosis
MH  - Shock, Cardiogenic/therapy
COIS- Disclosure: The authors have no conflicts of interest to report.
EDAT- 2023/05/08 18:42
MHDA- 2023/09/01 06:43
CRDT- 2023/05/08 16:23
PHST- 2023/09/01 06:43 [medline]
PHST- 2023/05/08 18:42 [pubmed]
PHST- 2023/05/08 16:23 [entrez]
AID - 00002480-990000000-00237 [pii]
AID - 10.1097/MAT.0000000000001982 [doi]
PST - ppublish
SO  - ASAIO J. 2023 Sep 1;69(9):873-878. doi: 10.1097/MAT.0000000000001982. Epub 2023 
      May 8.