PMID- 37156496 OWN - NLM STAT- MEDLINE DCOM- 20230510 LR - 20240502 IS - 1751-7893 (Electronic) IS - 1751-7885 (Print) IS - 1751-7885 (Linking) VI - 17 IP - 5 DP - 2023 May TI - Social network size in adolescents at clinical high risk for psychosis. PG - 462-469 LID - 10.1111/eip.13341 [doi] AB - AIMS: Adolescents and young adults at clinical high risk (CHR) for psychosis report few close friends. Social support has been linked to conversion to psychosis and psychosis relapse in CHR individuals. Expanding earlier research on loneliness and friendships at a single timepoint, this study described composition and changes in social network and its association with clinical and cognitive symptoms among CHR adolescents. METHODS: Ninety five individuals (46 CHR individuals, 49 healthy volunteers) completed baseline and 1-year follow-up Social Network Index (SNI) evaluations and clinical interviews. Analyses first examined SNI size and composition across 10 categories (e.g., family, close friends, coworkers, classmates) between groups. Then, the relationship between SNI size and baseline social symptoms (i.e., paranoia, social anhedonia, social anxiety, social cognition), social function, and changes in symptoms and social networks over 1-year were examined within the CHR group. RESULTS: CHR individuals showed smaller social networks overall, driven by fewer friendships and family relationships. Social cognition and social anxiety significantly related to SNI size at baseline, but social anhedonia and paranoia did not. SNI size related to social function, but with a modest effect size (r's = .45 and .56). Surprisingly, an increase in positive symptom severity related to an increase in familial but a decrease in coworker social network size. CONCLUSIONS: The social support deficits in the CHR group were specific to relatives and friendships, with social anxiety and social cognition as implicated symptoms. Social relationships may serve as a promising early intervention target in individuals at CHR for psychosis. CI - (c) 2022 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd. FAU - Ryan, Patrick C AU - Ryan PC AD - National Institute of Mental Health, Bethesda, Maryland, USA. FAU - Damme, Katherine S F AU - Damme KSF AUID- ORCID: 0000-0003-4260-1528 AD - Department of Psychology, Northwestern University, Evanston, Illinois, USA. AD - Institute for Innovations in Developmental Sciences (DevSci), Northwestern University, Evanston, Illinois, USA. FAU - Kuhney, Franchesca S AU - Kuhney FS AD - Department of Psychology, University of Illinois at Chicago, Chicago, Illinois, USA. FAU - Mittal, Vijay A AU - Mittal VA AD - Department of Psychology, Northwestern University, Evanston, Illinois, USA. AD - Institute for Innovations in Developmental Sciences (DevSci), Northwestern University, Evanston, Illinois, USA. AD - Department of Psychiatry, Northwestern University, Chicago, Illinois, USA. AD - Medical Social Sciences, Northwestern University, Chicago, Illinois, USA. AD - Institute for Policy Research (IPR), Northwestern University, Chicago, Illinois, USA. LA - eng GR - R33 MH103231/MH/NIMH NIH HHS/United States GR - T32 MH126368/MH/NIMH NIH HHS/United States GR - R01 MH112545/MH/NIMH NIH HHS/United States GR - R01 MH094650/MH/NIMH NIH HHS/United States GR - L30 MH124234/MH/NIMH NIH HHS/United States GR - R21 MH103231/MH/NIMH NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20220812 PL - Australia TA - Early Interv Psychiatry JT - Early intervention in psychiatry JID - 101320027 SB - IM MH - Young Adult MH - Humans MH - Adolescent MH - *Psychotic Disorders/psychology MH - Social Adjustment MH - Prodromal Symptoms PMC - PMC10167376 MID - NIHMS1826979 OTO - NOTNLM OT - psychosis risk OT - social anxiety OT - social cognition OT - social networks OT - social support EDAT- 2023/05/09 00:42 MHDA- 2023/05/10 06:42 PMCR- 2024/05/01 CRDT- 2023/05/08 19:43 PHST- 2022/05/12 00:00 [revised] PHST- 2022/01/17 00:00 [received] PHST- 2022/07/05 00:00 [accepted] PHST- 2023/05/10 06:42 [medline] PHST- 2023/05/09 00:42 [pubmed] PHST- 2023/05/08 19:43 [entrez] PHST- 2024/05/01 00:00 [pmc-release] AID - 10.1111/eip.13341 [doi] PST - ppublish SO - Early Interv Psychiatry. 2023 May;17(5):462-469. doi: 10.1111/eip.13341. Epub 2022 Aug 12.