PMID- 37166083
OWN - NLM
STAT- MEDLINE
DCOM- 20230802
LR  - 20230802
IS  - 2635-0114 (Electronic)
IS  - 2635-0106 (Linking)
VI  - 49
IP  - 4
DP  - 2023 Aug
TI  - Physical Activity and Its Synergistic Interaction With Low Platelet-Lymphocyte 
      Ratio Levels Increasing the Sleep Quality in Type 2 Diabetes Mellitus.
PG  - 303-313
LID - 10.1177/26350106231173675 [doi]
AB  - PURPOSE: The purpose of the study was to explore the effect of synergistic 
      interaction and the independence of physical activity and inflammatory markers, 
      including platelet-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio 
      (NLR), on sleep quality in persons with type 2 diabetes mellitus (T2DM). METHODS: 
      This descriptive cross-sectional study included 294 persons with T2DM in East 
      Java, Indonesia. Fasting blood was analyzed for inflammation markers, including 
      NLR and PLR. Physical activity and sleep quality were assessed using Metabolic 
      Equivalent of Task and Pittsburgh Sleep Quality Index, respectively. Multivariate 
      logistic regression, chi-square test, and independent t test were performed. 
      RESULTS: There was an independently significant relationship between physical 
      activity, NLR, and PLR with sleep quality. Persons with both active physical 
      activity and low PLRs were 12.52 times more likely to have high sleep quality 
      scores than those with low physical activity and high PLRs. A positive additive 
      interaction of active physical activity and low PLRs for high sleep quality 
      scores was identified. CONCLUSION: Physical activity, NLR, and PLR revealed an 
      independently significant relationship with sleep quality. Persons with both 
      active physical activity levels and low PLR were the most substantial synergistic 
      effect of high sleep quality. Further studies are necessary to examine the 
      problems and solutions for sleep quality in this population.
FAU - Rias, Yohanes Andy
AU  - Rias YA
AUID- ORCID: 0000-0001-5403-2161
AD  - Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand.
AD  - Faculty of Health and Medicine, College of Nursing, Institut Ilmu Kesehatan 
      Bhakti Wiyata, Kediri, Indonesia.
FAU - Thato, Ratsiri
AU  - Thato R
AD  - Faculty of Nursing, Chulalongkorn University, Bangkok, Thailand.
FAU - Tsai, Hsiu Ting
AU  - Tsai HT
AD  - Post-Baccalaureate Program in Nursing, College of Nursing, Taipei Medical 
      University, Taipei, Taiwan.
AD  - School of Nursing, College of Nursing, Taipei Medical University, Taipei Taiwan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230511
PL  - United States
TA  - Sci Diabetes Self Manag Care
JT  - The science of diabetes self-management and care
JID - 101775189
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Cross-Sectional Studies
MH  - Sleep Quality
MH  - Retrospective Studies
MH  - Lymphocytes
MH  - Exercise
EDAT- 2023/05/11 13:18
MHDA- 2023/08/02 06:42
CRDT- 2023/05/11 07:33
PHST- 2023/08/02 06:42 [medline]
PHST- 2023/05/11 13:18 [pubmed]
PHST- 2023/05/11 07:33 [entrez]
AID - 10.1177/26350106231173675 [doi]
PST - ppublish
SO  - Sci Diabetes Self Manag Care. 2023 Aug;49(4):303-313. doi: 
      10.1177/26350106231173675. Epub 2023 May 11.