PMID- 37171090
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20240228
IS  - 1879-1190 (Electronic)
IS  - 1072-7515 (Linking)
VI  - 237
IP  - 3
DP  - 2023 Sep 1
TI  - Determining the Minimum Clinically Important Difference for the European Hernia 
      Society Quality of Life Instrument in Inguinal Hernia Repair Patients.
PG  - 525-532
LID - 10.1097/XCS.0000000000000754 [doi]
AB  - BACKGROUND: Patient-reported outcomes in clinical research allow for a more 
      comprehensive and meaningful assessment of interventions but are subjective and 
      difficult to interpret. European Registry for Abdominal Wall Hernias-Quality of 
      Life (EuraHS-QoL) is a tool designed to assess perioperative quality of life for 
      patients undergoing inguinal hernia repair, one of the most performed operations 
      worldwide. Defining the minimum clinically important difference (MCID) for 
      EuraHS-QoL tool can help standardize its interpretation for research purposes and 
      facilitate improved shared decision making in clinical settings. STUDY DESIGN: A 
      combination of 3 approaches for estimating MCIDs was used in this study. First, 2 
      distribution-based approaches were used that based estimates on statistical 
      parameters of the data. The SEM provided a minimum value for the MCID, and 
      one-half of the SD provided a point estimate of the MCID. Second, anchor-based 
      approaches integrated patient perceptions of their overall well-being before and 
      after surgery to provide benchmarks for the MCID. Last, iterative surveys of 
      expert hernia surgeons were used to yield the final MCIDs for each domain and the 
      composite EuraHS-QoL score. RESULTS: The overall range of EuraHS-QoL is 0 to 90, 
      with subdomain ranges of 0 to 30 for the pain domain, 0 to 40 for the restriction 
      of activities domain, and 0 to 20 for the cosmesis domain, with higher scores 
      representing worse outcomes. The overall MCID for EuraHS-QoL is 10. 
      Domain-specific MCIDs are 3 for the pain domain, 5 for the restriction of 
      activities domain, and 2 for the cosmesis domain. CONCLUSIONS: In this study, we 
      define overall and domain-specific MCIDs for the EuraHS-QoL instrument using 
      statistical methods, patient-based methods, and clinical expertise, providing 
      estimates that are both statistically and clinically significant.
CI  - Copyright (c) 2023 by the American College of Surgeons. Published by Wolters Kluwer 
      Health, Inc. All rights reserved.
FAU - Shukla, Priya
AU  - Shukla P
AD  - From the Cleveland Clinic Lerner College of Medicine, Cleveland, OH (Shukla, 
      Zhao, Sharew).
FAU - Huang, Li-Ching
AU  - Huang LC
AD  - Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, 
      TN (Huang).
FAU - Zhao, Alison
AU  - Zhao A
AD  - From the Cleveland Clinic Lerner College of Medicine, Cleveland, OH (Shukla, 
      Zhao, Sharew).
FAU - Sharew, Betemariam
AU  - Sharew B
AD  - From the Cleveland Clinic Lerner College of Medicine, Cleveland, OH (Shukla, 
      Zhao, Sharew).
FAU - Miller, Ben
AU  - Miller B
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
FAU - Beffa, Lucas
AU  - Beffa L
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
FAU - Petro, Clayton C
AU  - Petro CC
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
FAU - Krpata, David M
AU  - Krpata DM
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
FAU - Prabhu, Ajita S
AU  - Prabhu AS
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
FAU - Rosen, Michael J
AU  - Rosen MJ
AD  - Center for Abdominal Core Health, Digestive Disease and Surgery Institute, 
      Cleveland Clinic Foundation, Cleveland, OH (Miller, Beffa, Petro, Krpata, Prabhu, 
      Rosen).
LA  - eng
PT  - Journal Article
DEP - 20230512
PL  - United States
TA  - J Am Coll Surg
JT  - Journal of the American College of Surgeons
JID - 9431305
SB  - IM
MH  - Humans
MH  - *Hernia, Inguinal/surgery
MH  - Quality of Life
MH  - Patient Reported Outcome Measures
MH  - Surveys and Questionnaires
MH  - Pain
EDAT- 2023/05/12 13:08
MHDA- 2023/12/17 09:42
CRDT- 2023/05/12 08:03
PHST- 2023/12/17 09:42 [medline]
PHST- 2023/05/12 13:08 [pubmed]
PHST- 2023/05/12 08:03 [entrez]
AID - 00019464-990000000-00662 [pii]
AID - 10.1097/XCS.0000000000000754 [doi]
PST - ppublish
SO  - J Am Coll Surg. 2023 Sep 1;237(3):525-532. doi: 10.1097/XCS.0000000000000754. 
      Epub 2023 May 12.