PMID- 37172296
OWN - NLM
STAT- MEDLINE
DCOM- 20230724
LR  - 20230724
IS  - 1612-1880 (Electronic)
IS  - 1612-1872 (Linking)
VI  - 20
IP  - 7
DP  - 2023 Jul
TI  - Response Surface Methodology-Based Optimized Ultrasonic-Assisted Extraction and 
      Characterization of Selected High-Value Components from Gemlik Olive Fruit.
PG  - e202300107
LID - 10.1002/cbdv.202300107 [doi]
AB  - This article presents an optimized ultrasound-assisted ethanolic extraction 
      (UAEE) and characterization of selected high-value components from Gemlik olive 
      fruit (GOF) harvested from Potohar region of Pakistan. Response surface 
      methodology (RSM), involving central composite design (CCD), was applied to 
      optimize the extraction variables i. e., temperature (25-65  degrees C), extraction time 
      (15-45 min) and aqueous ethanol concentration (60-90 %) for optimal recovery of 
      bioactives extract, total phenolic contents (TPC) and DPPH free radical 
      scavengers. Under the optimized set of conditions such as 43  degrees C temperature, 
      32 min extraction time and 80 % aqueous ethanol, the best extract yield 
      (218.82 mg/g), TPC (19.87 mg GAE/g) and DPPH scavenging activity (63.04 %) were 
      recorded. A quadratic polynomial model was found to be reasonably fitted to the 
      observed results for extract yield (p<0.0001 and R(2) =0.9941), TPC (p<0.0001 and 
      R(2) =0.9891), and DPPH radical scavenging activity (p<0.0001 and R(2) =0.9692). 
      Potent phenolic compounds were identified by GC/MS in GOF extract and 
      considerable amount of essential fatty acids were also detected. The current 
      findings support the use of UAEE as an effective green route for optimized 
      recovery of high-value components from GOF and hence its applications can be 
      extended to functional food and nutra-pharmaceutical developments.
CI  - (c) 2023 The Authors. Chemistry & Biodiversity published by Wiley-VHCA AG, Zurich, 
      Switzerland.
FAU - Ullah, Sami
AU  - Ullah S
AD  - Institute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
FAU - Anwar, Farooq
AU  - Anwar F
AD  - Institute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
AD  - Department of Food Science, Faculty of Food Science and Technology, Universiti 
      Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
FAU - Fayyaz Ur Rehman, Muhammad
AU  - Fayyaz Ur Rehman M
AD  - Institute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
FAU - Qadir, Rahman
AU  - Qadir R
AUID- ORCID: 0000-0002-0112-7594
AD  - Institute of Chemistry, University of Sargodha, Sargodha, 40100, Pakistan.
FAU - Safwan Akram, Muhammad
AU  - Safwan Akram M
AD  - School of Health and Life Sciences, Teesside University, Middlesbrough, TS1 3BA, 
      UK.
AD  - National Horizons Center, Teesside University, Darlington, DL11HG, United 
      Kingdom.
LA  - eng
GR  - TEE-3452/Teesside University/
PT  - Journal Article
DEP - 20230619
PL  - Switzerland
TA  - Chem Biodivers
JT  - Chemistry & biodiversity
JID - 101197449
RN  - 0 (Antioxidants)
RN  - 0 (Phenols)
RN  - 3K9958V90M (Ethanol)
RN  - 059QF0KO0R (Water)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - *Antioxidants/chemistry
MH  - Fruit/chemistry
MH  - Ultrasonics/methods
MH  - *Olea
MH  - Phenols/chemistry
MH  - Ethanol
MH  - Water
MH  - Plant Extracts/chemistry
OTO - NOTNLM
OT  - GC/MS
OT  - Olea europaea
OT  - antioxidants
OT  - p-coumaric acid
OT  - tocopherols
EDAT- 2023/05/12 19:07
MHDA- 2023/07/24 06:42
CRDT- 2023/05/12 16:32
PHST- 2023/01/21 00:00 [received]
PHST- 2023/05/10 00:00 [accepted]
PHST- 2023/07/24 06:42 [medline]
PHST- 2023/05/12 19:07 [pubmed]
PHST- 2023/05/12 16:32 [entrez]
AID - 10.1002/cbdv.202300107 [doi]
PST - ppublish
SO  - Chem Biodivers. 2023 Jul;20(7):e202300107. doi: 10.1002/cbdv.202300107. Epub 2023 
      Jun 19.