PMID- 37176733
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230515
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 12
IP  - 9
DP  - 2023 May 5
TI  - Does Tobacco Smoking Affect the Postoperative Outcome of MIS Lumbar Decompression 
      Surgery?
LID - 10.3390/jcm12093292 [doi]
LID - 3292
AB  - BACKGROUND: Tobacco smoking is a major cause of morbidity and mortality 
      worldwide. Several authors reported a significant negative impact of smoking on 
      the outcome of spinal surgeries. However, comparative studies on the effect of 
      smoking on the outcome of minimally invasive (MIS) spinal decompression are rare 
      with conflicting results. In this study, we aimed to evaluate clinical outcomes 
      and postoperative complications following MIS decompression in current and former 
      smoking patients compared to those of non-smoking patients. METHODS: We used our 
      prospectively collected database to retrospectively analyse the records of 188 
      consecutive patients treated with MIS lumbar decompression at our institution 
      between November 2013 and July 2017. Patients were divided into groups of smokers 
      (S), previous smokers (PS) and non-smokers (N). The S group and the PS group 
      comprised 31 and 40 patients, respectively. The N group included 117 patients. 
      The outcome measures included perioperative complications, revision surgery and 
      length of stay. Patient-reported outcome measures included a visual analogue 
      scale (VAS) for back pain and leg pain, as well as the Oswestry disability index 
      (ODI) for evaluating functional outcomes. RESULTS: Demographic variables, 
      comorbidity and other preoperative variables were comparable between the three 
      groups. A comparison of perioperative complications and revision surgery rates 
      showed no significant difference between the groups. All groups showed 
      significant improvement in their ODI and VAS scores at 12 and 24 months following 
      surgery. As shown by a multivariate analysis, current smokers had lower chances 
      of improvement, exceeding the minimal clinical important difference (MCID) in ODI 
      and VAS for leg pain at 12 months but not 24 months postoperatively. CONCLUSIONS: 
      Our findings show that except for a possible delay in improvement in leg pain and 
      disability, tobacco smoking has no substantial adverse impact on complications 
      and revision rates following MIS spinal decompressions.
FAU - Khashan, Morsi
AU  - Khashan M
AUID- ORCID: 0000-0001-8557-879X
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Ofir, Dror
AU  - Ofir D
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Hochberg, Uri
AU  - Hochberg U
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Schermann, Haggai
AU  - Schermann H
AUID- ORCID: 0000-0002-9271-6932
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Regev, Gilad J
AU  - Regev GJ
AUID- ORCID: 0000-0002-4079-1068
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Lidar, Zvi
AU  - Lidar Z
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
FAU - Salame, Khalil
AU  - Salame K
AD  - Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv 
      University, Tel Aviv 6423906, Israel.
LA  - eng
PT  - Journal Article
DEP - 20230505
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC10179248
OTO - NOTNLM
OT  - decompression
OT  - minimally invasive
OT  - radiculopathy
OT  - smoking
OT  - spine surgery
COIS- The authors declare no conflict of interest.
EDAT- 2023/05/13 15:12
MHDA- 2023/05/13 15:13
PMCR- 2023/05/05
CRDT- 2023/05/13 01:34
PHST- 2023/03/19 00:00 [received]
PHST- 2023/04/27 00:00 [revised]
PHST- 2023/05/03 00:00 [accepted]
PHST- 2023/05/13 15:13 [medline]
PHST- 2023/05/13 15:12 [pubmed]
PHST- 2023/05/13 01:34 [entrez]
PHST- 2023/05/05 00:00 [pmc-release]
AID - jcm12093292 [pii]
AID - jcm-12-03292 [pii]
AID - 10.3390/jcm12093292 [doi]
PST - epublish
SO  - J Clin Med. 2023 May 5;12(9):3292. doi: 10.3390/jcm12093292.