PMID- 37180612 OWN - NLM STAT- MEDLINE DCOM- 20230921 LR - 20230921 IS - 1661-8564 (Electronic) IS - 1661-8556 (Print) IS - 1661-8556 (Linking) VI - 68 DP - 2023 TI - Predicting the Risk of Type 2 Diabetes Mellitus with the New Chinese Diabetes Risk Score in a Cohort Study. PG - 1605611 LID - 10.3389/ijph.2023.1605611 [doi] LID - 1605611 AB - Objectives: The New Chinese Diabetes Risk Score (NCDRS) is a noninvasive tool to assess the risk of type 2 diabetes mellitus (T2DM) in the Chinese population. Our study aimed to evaluate the performance of the NCDRS in predicting T2DM risk with a large cohort. Methods: The NCDRS was calculated, and participants were categorized into groups by optimal cutoff or quartiles. Hazard ratios (HRs) and 95% confidential intervals (CIs) in Cox proportional hazards models were used to estimate the association between the baseline NCDRS and the risk of T2DM. The performance of the NCDRS was assessed by the area under the curve (AUC). Results: The T2DM risk was significantly increased in participants with NCDRS >/=25 (HR = 2.12, 95% CI 1.88-2.39) compared with NCDRS <25 after adjusting for potential confounders. T2DM risk also showed a significant increasing trend from the lowest to the highest quartile of NCDRS. The AUC was 0.777 (95% CI 0.640-0.786) with a cutoff of 25.50. Conclusion: The NCDRS had a significant positive association with T2DM risk, and the NCDRS is valid for T2DM screening in China. CI - Copyright (c) 2023 Chen, She, Dai, Wang, Tao, Huang, Xu, Lou, Hu, Li and Wang. FAU - Chen, Hongen AU - Chen H AD - Department of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China. FAU - She, Yuhang AU - She Y AD - Injury Prevention Research Center, Shantou University Medical College, Shantou, China. AD - School of Public Health, Shantou University, Shantou, China. FAU - Dai, Shuhong AU - Dai S AD - Department of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China. FAU - Wang, Li AU - Wang L AD - Department of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China. FAU - Tao, Na AU - Tao N AD - Department of Pharmacy, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China. FAU - Huang, Shaofen AU - Huang S AD - Shenzhen Nanshan District Shekou People's Hospital, Shenzhen, China. FAU - Xu, Shan AU - Xu S AD - Department of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China. FAU - Lou, Yanmei AU - Lou Y AD - Department of Health Management, Beijing Xiao Tang Shan Hospital, Beijing, China. FAU - Hu, Fulan AU - Hu F AD - Department of Epidemiology and Health Statistics, School of Public Health, Shenzhen University Health Science Center, Shenzhen, China. FAU - Li, Liping AU - Li L AD - Injury Prevention Research Center, Shantou University Medical College, Shantou, China. AD - School of Public Health, Shantou University, Shantou, China. FAU - Wang, Changyi AU - Wang C AD - Department of Non-Communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control, Shenzhen, China. LA - eng PT - Journal Article DEP - 20230425 PL - Switzerland TA - Int J Public Health JT - International journal of public health JID - 101304551 SB - IM MH - Humans MH - China/epidemiology MH - Cohort Studies MH - *Diabetes Mellitus, Type 2/diagnosis/epidemiology MH - East Asian People MH - Risk Factors PMC - PMC10166829 OTO - NOTNLM OT - China OT - T2DM OT - cohort study OT - new Chinese diabetes risk score OT - screening COIS- The authors declare that they do not have any conflicts of interest. EDAT- 2023/05/14 19:13 MHDA- 2023/05/16 06:42 PMCR- 2023/04/25 CRDT- 2023/05/14 12:08 PHST- 2022/11/21 00:00 [received] PHST- 2023/03/27 00:00 [accepted] PHST- 2023/05/14 19:13 [pubmed] PHST- 2023/05/16 06:42 [medline] PHST- 2023/05/14 12:08 [entrez] PHST- 2023/04/25 00:00 [pmc-release] AID - 1605611 [pii] AID - 10.3389/ijph.2023.1605611 [doi] PST - epublish SO - Int J Public Health. 2023 Apr 25;68:1605611. doi: 10.3389/ijph.2023.1605611. eCollection 2023.