PMID- 37181472 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230516 IS - 2514-2119 (Electronic) IS - 2514-2119 (Linking) VI - 7 IP - 5 DP - 2023 May TI - Combined approach of carotid endarteriectomy and transcarotid transcatheter aortic valve implantation as a minimally invasive one-step treatment of aortic stenosis: a case report. PG - ytad184 LID - 10.1093/ehjcr/ytad184 [doi] LID - ytad184 AB - BACKGROUND: Despite the gold-standard approach for transaortic valve implantation (TAVI) remains transfemoral (TF), alternative approaches are needed in patients who present contraindications to transfemoral access. CASE SUMMARY: We report the case of a 79-year-old female with a symptomatic high-gradient severe aortic stenosis-mean gradient of 43 mmHg-and a significant supra-aortic trunk stenosis (left carotid artery: 90-99%; right carotid artery: 50-70%), and who was hospitalized for progressive dyspnoea New York Heart Association (NYHA) stage III. In this high-risk patient, it was decided to perform a TAVI. Because of a history of stenting of both common iliac arteries in a context of an arterial insufficiency of the lower limbs (Leriche classification stage III) and stenotic thoraco-abdominal aorta atheromatosis, an alternative approach to the transfemoral transaortic valve implantation (TF-TAVI) one was needed. It was decided to perform a combined transcarotid-TAVI (TC-TAVI) with EDWARDS S3 23 mm valve with a left endarteriectomy during the same operating time. DISCUSSION: Our case illustrates an alternative approach to perform a percutaneous aortic valve implantation, despite supra-aortic trunk stenosis, in a high-risk surgical patient contraindicated to a TF-TAVI. Transcarotid transaortic valve implantation remains a safe alternative when TF-TAVI is contraindicated, and the combined approach of carotid endarteriectomy and TC-TAVI offers a minimally invasive one-step treatment in high operative risk patients. CI - (c) The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. FAU - Bourlond, Baudouin AU - Bourlond B AUID- ORCID: 0000-0002-9340-2521 AD - Department of Cardiology, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland. FAU - Dulguerov, Filip AU - Dulguerov F AD - Department of Cardiac Surgery, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland. FAU - Longchamp, Justine AU - Longchamp J AD - Department of Vascular Surgery, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland. FAU - Kirsch, Matthias AU - Kirsch M AUID- ORCID: 0000-0002-9213-7578 AD - Department of Cardiac Surgery, Lausanne University Hospital (CHUV), Rue du Bugnon 46, 1011 Lausanne, Switzerland. LA - eng PT - Case Reports DEP - 20230503 PL - England TA - Eur Heart J Case Rep JT - European heart journal. Case reports JID - 101730741 PMC - PMC10171836 OTO - NOTNLM OT - Aortic stenosis OT - Case report OT - Minimally invasive OT - TAVI OT - TAVR OT - Transcarotid-TAVI COIS- Conflict of interest: None declared. EDAT- 2023/05/14 19:13 MHDA- 2023/05/14 19:14 PMCR- 2023/05/03 CRDT- 2023/05/14 12:19 PHST- 2022/07/05 00:00 [received] PHST- 2022/09/05 00:00 [revised] PHST- 2023/04/12 00:00 [accepted] PHST- 2023/05/14 19:14 [medline] PHST- 2023/05/14 19:13 [pubmed] PHST- 2023/05/14 12:19 [entrez] PHST- 2023/05/03 00:00 [pmc-release] AID - ytad184 [pii] AID - 10.1093/ehjcr/ytad184 [doi] PST - epublish SO - Eur Heart J Case Rep. 2023 May 3;7(5):ytad184. doi: 10.1093/ehjcr/ytad184. eCollection 2023 May.