PMID- 37190570
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230519
IS  - 2076-3425 (Print)
IS  - 2076-3425 (Electronic)
IS  - 2076-3425 (Linking)
VI  - 13
IP  - 4
DP  - 2023 Apr 3
TI  - Analysis of the Relationship between Higher-Order Factor Structure of Personality 
      Disorders and the Five-Factor Model of Personality.
LID - 10.3390/brainsci13040605 [doi]
LID - 605
AB  - The growing body of evidence on the dimensional classification of personality 
      disorders (PD) has resulted in its acceptance in the ICD-11 classification, which 
      abolished categories and retains only a general description of PD. Specifying the 
      type of PD is optional, and the suggested domains represent maladaptive variants 
      of the five-factor model of personality (FFM). The aim of our study was to 
      explore the existence of a joint structure between maladaptive and normal 
      personality traits, and to investigate how these structures are integrated. The 
      study included 223 patients who had been diagnosed with PD and completed the 
      Structured Clinical Interview for DSM-5 Personality Disorders and the NEO 
      Personality Inventory-Revised (NEO-PI-R). To determine the degree of overlap 
      between PD domains and NEO PI-R scales, a canonical analysis of covariance was 
      conducted. Our findings showed a relationship between the internalizing PD 
      spectrum (consisting of avoidant, dependent, and borderline traits with detached 
      and anankastic traits) and high neuroticism, low conscientiousness, and 
      moderately low agreeableness and extroversion, suggesting the existence of a 
      broad personality disorder factor. However, the internalizing dimensions 
      exhibited a more pronounced effect within this construct. Furthermore, we 
      identified a second function that demonstrated a link between the externalizing 
      PD spectrum (including narcissistic, histrionic, and antisocial traits) and high 
      extraversion, high openness, and low agreeableness, suggesting the existence of 
      an externalizing factor. Overall, our findings provide evidence for a joint 
      structure of maladaptive and normal personality traits in a sample of personality 
      disorders and emphasize the importance of integrating the FFM model in PD 
      evaluation in clinical practice, suggesting that differentiating between major 
      subgroups could assist in adjusting therapeutic approaches.
FAU - Pesic, Danilo
AU  - Pesic D
AUID- ORCID: 0000-0002-7588-0511
AD  - Clinic for Children and Adolescence, Institute of Mental Health, 11000 Belgrade, 
      Serbia.
AD  - School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
FAU - Lecic-Tosevski, Dusica
AU  - Lecic-Tosevski D
AD  - Serbian Academy of Sciences and Arts, 11000 Belgrade, Serbia.
FAU - Kalanj, Marko
AU  - Kalanj M
AD  - Clinic for Children and Adolescence, Institute of Mental Health, 11000 Belgrade, 
      Serbia.
FAU - Ristic, Ivan
AU  - Ristic I
AD  - Clinical Department for Psychotic Disorders, Institute of Mental Health, 11000 
      Belgrade, Serbia.
FAU - Vukovic, Olivera
AU  - Vukovic O
AD  - School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
AD  - Department for Research and Education, Institute of Mental Health, 11000 
      Belgrade, Serbia.
FAU - Pejuskovic, Bojana
AU  - Pejuskovic B
AUID- ORCID: 0000-0001-7879-5745
AD  - School of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
AD  - Clinical Department for Crisis intervention and Affective Disorders, Head, 
      Institute of Mental Health, 11000 Belgrade, Serbia.
LA  - eng
PT  - Journal Article
DEP - 20230403
PL  - Switzerland
TA  - Brain Sci
JT  - Brain sciences
JID - 101598646
PMC - PMC10136835
OTO - NOTNLM
OT  - ICD-11 classification
OT  - broad personality disorder factor
OT  - canonical analysis of covariance
OT  - five factor model of personality
OT  - metatraits
OT  - personality disorder
COIS- Dusica Lecic Tosevski is a member of the WHO Working Group for ICD-11 Personality 
      Disorders Classification.
EDAT- 2023/05/16 06:42
MHDA- 2023/05/16 06:43
PMCR- 2023/04/03
CRDT- 2023/05/16 01:15
PHST- 2023/02/28 00:00 [received]
PHST- 2023/03/23 00:00 [revised]
PHST- 2023/03/29 00:00 [accepted]
PHST- 2023/05/16 06:43 [medline]
PHST- 2023/05/16 06:42 [pubmed]
PHST- 2023/05/16 01:15 [entrez]
PHST- 2023/04/03 00:00 [pmc-release]
AID - brainsci13040605 [pii]
AID - brainsci-13-00605 [pii]
AID - 10.3390/brainsci13040605 [doi]
PST - epublish
SO  - Brain Sci. 2023 Apr 3;13(4):605. doi: 10.3390/brainsci13040605.