PMID- 37202787
OWN - NLM
STAT- MEDLINE
DCOM- 20230522
LR  - 20230522
IS  - 1746-1596 (Electronic)
IS  - 1746-1596 (Linking)
VI  - 18
IP  - 1
DP  - 2023 May 18
TI  - Feasibility of fine needle aspiration for diagnosis of b-cell lymphoma of the 
      thyroid: a case series and review of the literature.
PG  - 69
LID - 10.1186/s13000-023-01346-4 [doi]
LID - 69
AB  - BACKGROUND: Primary thyroid lymphoma (PTL) is a rare cancer accounting for 
      approximately 5% of thyroid malignancies. Historically, incisional biopsy has 
      been the gold standard for definitive diagnosis of PTL, however, the use of cell 
      block as an adjunct to fine needle aspiration (FNA) provides a high sensitivity 
      and specificity for diagnosis and classification. METHODS: Three patients 
      presented with a symptomatic enlarging thyroid mass. Patient 1 underwent 
      incisional biopsy under general anesthesia, Patient 2 underwent core needle 
      biopsy to avoid high risk intubation, and Patient 3 underwent fine needle 
      aspiration alone with the use of cell block. RESULTS: All patients were diagnosed 
      with a fully classified non-Hodgkin's lymphoma using immunohistochemistry, flow 
      cytometry, and fluorescence in situ hybridization (FISH) analysis. CONCLUSIONS: 
      FNA for diagnosis of some subtypes of PTL is feasible and preferred in cases that 
      are particularly high risk for general anesthesia. This minimally invasive 
      technique is safe and cost effective as it avoids expenses associated with 
      operative intervention.
CI  - (c) 2023. The Author(s).
FAU - Karabachev, Alexander D
AU  - Karabachev AD
AD  - Department of Otolaryngology, University of Cincinnati Medical Center, 
      Cincinnati, OH, USA. karabaar@ucmail.uc.edu.
AD  - Robert Larner College of Medicine, University of Vermont, Burlington, VT, USA. 
      karabaar@ucmail.uc.edu.
FAU - Brundage, William J
AU  - Brundage WJ
AD  - Robert Larner College of Medicine, University of Vermont, Burlington, VT, USA.
AD  - Department of Surgery, Division of Otolaryngology, University of Vermont Medical 
      Center, Burlington, VT, USA.
FAU - Sajisevi, Mirabelle B
AU  - Sajisevi MB
AD  - Robert Larner College of Medicine, University of Vermont, Burlington, VT, USA.
AD  - Department of Surgery, Division of Otolaryngology, University of Vermont Medical 
      Center, Burlington, VT, USA.
FAU - Ciolino, Allison L
AU  - Ciolino AL
AD  - Robert Larner College of Medicine, University of Vermont, Burlington, VT, USA.
AD  - Department of Pathology and Laboratory Medicine, University of Vermont Medical 
      Center, Burlington, VT, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230518
PL  - England
TA  - Diagn Pathol
JT  - Diagnostic pathology
JID - 101251558
SB  - IM
MH  - Humans
MH  - Biopsy, Fine-Needle/methods
MH  - In Situ Hybridization, Fluorescence
MH  - Feasibility Studies
MH  - *Lymphoma, B-Cell/diagnosis
MH  - *Lymphoma/pathology
MH  - *Thyroid Neoplasms/diagnosis/pathology
PMC - PMC10193605
OTO - NOTNLM
OT  - Cell block
OT  - Diagnosis
OT  - Fine needle aspiration
OT  - Pathology
OT  - Thyroid cancer-clinical
OT  - Thyroid lymphoma
COIS- There are no competing interests with any of the authors or individuals mentioned 
      in our acknowledgments.
EDAT- 2023/05/19 01:05
MHDA- 2023/05/22 06:42
PMCR- 2023/05/18
CRDT- 2023/05/18 23:33
PHST- 2022/11/09 00:00 [received]
PHST- 2023/04/25 00:00 [accepted]
PHST- 2023/05/22 06:42 [medline]
PHST- 2023/05/19 01:05 [pubmed]
PHST- 2023/05/18 23:33 [entrez]
PHST- 2023/05/18 00:00 [pmc-release]
AID - 10.1186/s13000-023-01346-4 [pii]
AID - 1346 [pii]
AID - 10.1186/s13000-023-01346-4 [doi]
PST - epublish
SO  - Diagn Pathol. 2023 May 18;18(1):69. doi: 10.1186/s13000-023-01346-4.