PMID- 37206865
OWN - NLM
STAT- MEDLINE
DCOM- 20230522
LR  - 20230523
IS  - 2296-2565 (Electronic)
IS  - 2296-2565 (Linking)
VI  - 11
DP  - 2023
TI  - Associations of long-term exposure to air pollution, physical activity with blood 
      pressure and prevalence of hypertension: the China Health and Retirement 
      Longitudinal Study.
PG  - 1137118
LID - 10.3389/fpubh.2023.1137118 [doi]
LID - 1137118
AB  - BACKGROUND: Long-term exposure to air pollution and physical activity (PA) are 
      linked to blood pressure and hypertension. However, the joint effect of air 
      pollution and PA on blood pressure and hypertension are still unknown in Chinese 
      middle-aged and older adults. METHODS: A total of 14,622 middle-aged and older 
      adults from the China Health and Retirement Longitudinal Study wave 3 were 
      included in this study. Ambient air pollution [particulate matter with 
      diameter </= 2.5 mum (PM(2.5)), or </=10 mum (PM(10)), sulfur dioxide (SO(2)), nitrogen 
      dioxide (NO(2)), carbonic oxide (CO)] were estimated using satellite-based 
      spatiotemporal models. PA was investigated using International Physical Activity 
      Questionnaire. Generalized linear models were used to examine the associations of 
      air pollution, PA score with blood pressure [systolic blood pressure (SBP), 
      diastolic blood pressure (DBP), and mean arterial pressure (MAP)], and the 
      prevalence of hypertension. Subgroup analysis was conducted to investigate the 
      effects of air pollution on blood pressure and the prevalence of hypertension in 
      different PA groups. RESULTS: The results showed that for each inter-quartile 
      range (IQR) increase in PM(2.5) (25.45 mug/m(3)), PM(10) (40.56 mug/m(3)), SO(2) 
      (18.61 mug/m(3)), NO(2) (11.16 mug/m(3)), CO (0.42 mg/m(3)) and PA score (161.3 
      MET/h-week), the adjusted odd ratio (OR) of hypertension was 1.207 (95% 
      confidence interval (CI): 1.137, 1.281), 1.189 (95%CI: 1.122, 1.260), 1.186 
      (95%CI: 1.112, 1.266), 1.186 (95%CI: 1.116, 1.260), 1.288 (95%CI: 1.223, 1.357), 
      0.948 (95%CI: 0.899, 0.999), respectively. Long-term exposure to PM(2.5), PM(10), 
      SO(2), NO(2), and CO was associated with increased SBP, DBP, and MAP levels. For 
      example, each IQR increase in PM(2.5) was associated with 1.20 mmHg (95%CI: 0.69, 
      1.72) change in SBP, 0.66 mmHg (95%CI: 0.36, 0.97) change in DBP, and 0.84 mmHg 
      (95%CI: 0.49, 1.19) change in MAP levels, respectively. Each IQR increase in PA 
      score was associated with -0.56 mmHg (95%CI: -1.03, -0.09) change in SBP, 
      -0.32 mmHg (95%CI: -0.59, -0.05) change in DBP, and -0.33 mmHg (95%CI: -0.64, 
      -0.02) change in MAP levels, respectively. Subgroup analysis found that the 
      estimated effects in the sufficient PA group were lower than that in the 
      insufficient PA group. CONCLUSION: Long-term exposure to air pollutants is 
      associated with increased blood pressure and hypertension risk, while high-level 
      PA is associated with decreased blood pressure and hypertension risk. 
      Strengthening PA might attenuate the adverse effects of air pollution on blood 
      pressure and hypertension risk.
CI  - Copyright (c) 2023 Zhang, Zhang, Xin, Duan, Wei, Zhang, Han and Niu.
FAU - Zhang, Jinglong
AU  - Zhang J
AD  - Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military 
      Medical University, Xi'an, China.
FAU - Zhang, Fen
AU  - Zhang F
AD  - Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical 
      University, Xi'an, China.
FAU - Xin, Chao
AU  - Xin C
AD  - PLA Rocket Force Characteristic Medical Center, Beijing, China.
FAU - Duan, Zhizhou
AU  - Duan Z
AD  - Preventive Health Service, Jiangxi Provincial People's Hospital, The First 
      Affiliated Hospital of Nanchang Medical College, Nanchang, China.
FAU - Wei, Jing
AU  - Wei J
AD  - Department of Atmospheric and Oceanic Science, Earth System Science 
      Interdisciplinary Center, University of Maryland, College Park, MD, United 
      States.
FAU - Zhang, Xi
AU  - Zhang X
AD  - The First Clinical Medical College, Anhui Medical University, Hefei, Anhui, 
      China.
FAU - Han, Shichao
AU  - Han S
AD  - Department of Urology, Xijing Hospital, The Fourth Military Medical University, 
      Xi'an, China.
FAU - Niu, Zhiping
AU  - Niu Z
AD  - Department of Urology, Xijing Hospital, The Fourth Military Medical University, 
      Xi'an, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230503
PL  - Switzerland
TA  - Front Public Health
JT  - Frontiers in public health
JID - 101616579
RN  - S7G510RUBH (Nitrogen Dioxide)
RN  - 0 (Air Pollutants)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - Middle Aged
MH  - Humans
MH  - Aged
MH  - Blood Pressure
MH  - Nitrogen Dioxide/adverse effects/analysis
MH  - Longitudinal Studies
MH  - Retirement
MH  - Prevalence
MH  - Environmental Exposure/adverse effects
MH  - *Hypertension/epidemiology/etiology
MH  - *Air Pollution/analysis
MH  - *Air Pollutants/analysis
MH  - Particulate Matter/adverse effects/analysis
MH  - China/epidemiology
MH  - Exercise
PMC - PMC10189054
OTO - NOTNLM
OT  - air pollution
OT  - blood pressure
OT  - cardiovascular system
OT  - hypertension
OT  - middle-aged and older adults
OT  - physical activity
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/05/19 19:14
MHDA- 2023/05/22 06:42
PMCR- 2023/05/03
CRDT- 2023/05/19 15:46
PHST- 2023/01/04 00:00 [received]
PHST- 2023/04/10 00:00 [accepted]
PHST- 2023/05/22 06:42 [medline]
PHST- 2023/05/19 19:14 [pubmed]
PHST- 2023/05/19 15:46 [entrez]
PHST- 2023/05/03 00:00 [pmc-release]
AID - 10.3389/fpubh.2023.1137118 [doi]
PST - epublish
SO  - Front Public Health. 2023 May 3;11:1137118. doi: 10.3389/fpubh.2023.1137118. 
      eCollection 2023.