PMID- 37211669
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230701
IS  - 1976-1902 (Print)
IS  - 1976-7846 (Electronic)
IS  - 1976-1902 (Linking)
VI  - 17
IP  - 3
DP  - 2023 Jun
TI  - Does Baseline Severity of Arm Pain Influence Outcomes Following Single-Level 
      Anterior Cervical Discectomy and Fusion?
PG  - 500-510
LID - 10.31616/asj.2022.0027 [doi]
AB  - STUDY DESIGN: Retrospective cohort. PURPOSE: To assess preoperative arm pain 
      severity influence on postoperative patient-reported outcomes measures (PROMs) 
      and minimal clinically important difference (MCID) achievement following 
      single-level anterior cervical discectomy and fusion (ACDF). OVERVIEW OF 
      LITERATURE: There is evidence that preoperative symptom severity can affect 
      postoperative outcomes. Few have evaluated this association between preoperative 
      arm pain severity and postoperative PROMs and MCID achievement following ACDF. 
      METHODS: Individuals undergoing single-level ACDF were identified. Patients were 
      grouped by preoperative Visual Analog Scale (VAS) arm </=8 vs. >8. PROMs collected 
      preoperatively and postoperatively included VAS-arm/VAS-neck/Neck Disability 
      Index (NDI)/12-item Short Form (SF-12) Physical Composite Score (PCS)/SF-12 
      mental composite score (MCS)/Patient-Reported Outcomes Measurement Information 
      System physical function (PROMIS-PF). Demographics, PROMs, and MCID rates were 
      compared between cohorts. RESULTS: A total of 128 patients were included. The VAS 
      arm </=8 cohort significantly improved for all PROMs excepting VAS arm at 
      1-year/2-years, SF-12 MCS at 12-weeks/1-year/2-years, and SF-12 PCS/PROMIS-PF at 
      6-weeks, only (p </=0.021, all). The VAS arm >8 cohort significantly improved for 
      VAS neck at all timepoints, VAS arm from 6-weeks to 1-year, NDI from 6-weeks to 
      6-months, and SF-12 MCS/PROMIS-PF at 6-months (p </=0.038, all). Postoperatively, 
      the VAS arm >8 cohort had higher VAS-neck (6 weeks/6 months), VAS-arm (12 weeks/6 
      months), NDI (6 weeks/6 months), lower SF-12 MCS (6 weeks/6 months), SF-12 PCS (6 
      months), and PROMISPF (12 weeks/6 months) (p </=0.038, all). MCID achievement rates 
      were higher among the VAS arm >8 cohort for the VAS-arm at 
      6-weeks/12-weeks/1-year/overall and NDI at 2 years (p </=0.038, all). CONCLUSIONS: 
      Significance in PROM score differences between VAS arm </=8 vs. >8 generally 
      dissipated at the 1-year and 2-year timepoint, although higher preoperative arm 
      pain patients suffered from worse pain, disability, and mental/physical function 
      scores. Furthermore, clinically meaningful rates of improvement were similar 
      throughout the vast majority of timepoints for all PROMs studied.
FAU - Patel, Madhav R
AU  - Patel MR
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Jacob, Kevin C
AU  - Jacob KC
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Chavez, Frank A
AU  - Chavez FA
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Parsons, Alexander W
AU  - Parsons AW
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Vanjani, Nisheka N
AU  - Vanjani NN
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Pawlowski, Hanna
AU  - Pawlowski H
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Prabhu, Michael C
AU  - Prabhu MC
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, 
      USA.
LA  - eng
PT  - Journal Article
DEP - 20230522
PL  - Korea (South)
TA  - Asian Spine J
JT  - Asian spine journal
JID - 101314177
PMC - PMC10300895
OTO - NOTNLM
OT  - Anterior cervical discectomy and fusion
OT  - Minimal clinically important difference
OT  - Patient reported outcome measures
OT  - Visual Analog Scale arm
COIS- Conflict of Interest No potential conflict of interest relevant to this article 
      was reported.
EDAT- 2023/05/22 06:42
MHDA- 2023/05/22 06:43
PMCR- 2023/06/01
CRDT- 2023/05/22 00:32
PHST- 2022/01/11 00:00 [received]
PHST- 2022/06/07 00:00 [accepted]
PHST- 2023/05/22 06:43 [medline]
PHST- 2023/05/22 06:42 [pubmed]
PHST- 2023/05/22 00:32 [entrez]
PHST- 2023/06/01 00:00 [pmc-release]
AID - asj.2022.0027 [pii]
AID - asj-2022-0027 [pii]
AID - 10.31616/asj.2022.0027 [doi]
PST - ppublish
SO  - Asian Spine J. 2023 Jun;17(3):500-510. doi: 10.31616/asj.2022.0027. Epub 2023 May 
      22.