PMID- 37212855 OWN - NLM STAT- MEDLINE DCOM- 20230616 LR - 20230616 IS - 2282-4197 (Electronic) IS - 1124-3562 (Linking) VI - 95 IP - 2 DP - 2023 May 22 TI - Enhanced recovery after retrograde intra-renal surgery (RIRS) in comparison with mini-percutaneous nephrolithotomy (Mini-PCNL) for renal stone treatment. PG - 10991 LID - 10.4081/aiua.2023.10991 [doi] AB - OBJECTIVES: The study presents a comparative analysis of the mini-percutaneous nephrolithotripsy (mini-PCNL) and retrograde nephrolithotripsy (RIRS) with a logistic analysis of outcomes and complications. MATERIAL AND METHODS: The prospective study included 50 patients diagnosed with urolithiasis from 2018 to 2021 in the urological hospitals in Irkutsk. Patients were divided into two groups: RIRS (group I, n = 23) and Mini-PCNL (group II, n = 27). The comparison groups are statistically homogeneous. RESULTS: Both procedures equally lead to high stone free rates (SFR > 1 mm, 91.3% vs 85.1%; p = 0.867; SFR > 2 mm, 95.6% vs 92.5%; p = 0.936). The intergroup analysis of the total operation time (and lithotripsy) demonstrated similar times (p > 0.05). Postoperative complications of classes II-III (Clavien-Dindo) in the early and late postoperative period developed rarely and were comparable (p > 0.05). Class I complications were predominant in the PCNL group (p = 0.007). Some parameters demonstrated the superiority of RIRS over PCNL: less pronounced pain syndrome (p = 0.002), less drainage time (p < 0.001), no postoperative hematuria (p = 0.002), shorter hospitalization and total treatment period (p < 0.001). CONCLUSIONS: The study highlighted the positive effect of the oneday surgery principle on the risk of developing postoperative hematuria, urinary infection, or severe postoperative pain. RIRS and mini-PCNL have similar effectiveness, but RIRS meets the criteria of the enhanced recovery program more than PCNL. FAU - Vorobev, Vladimir AU - Vorobev V AD - Department of General Surgery, Irkutsk State Medical University, Irkutsk. vorobevr782192@rambler.ru. FAU - Beloborodov, Vladimir AU - Beloborodov V AD - Department of General Surgery, Irkutsk State Medical University, Irkutsk. vbeloborodov391@rambler.ru. FAU - Hovalyg, Temirlan AU - Hovalyg T AD - Department of General Surgery, Irkutsk State Medical University, Irkutsk. temirlan_hovalyg@rambler.ru. FAU - Seminskiy, Igor AU - Seminskiy I AD - Department of Pathology, Irkutsk State Medical University, Irkutsk. seminskiy.igor@rambler.ru. FAU - Sherbatykh, Andrey AU - Sherbatykh A AD - Department of Faculty Surgery, Irkutsk State Medical University, Irkutsk. andsherbatykh3@rambler.ru. FAU - Shaderkin, Igor AU - Shaderkin I AD - E-Health Laboratory, I.M. Sechenov First Moscow State Medical University, Moscow. igshaderkin@rambler.ru. FAU - Firsov, Mikhail AU - Firsov M AD - Department of Urology, Andrology and Sexology, Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Krasnoyarsk. m_firsov31@rambler.ru. LA - eng PT - Journal Article DEP - 20230522 PL - Italy TA - Arch Ital Urol Androl JT - Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica JID - 9308247 SB - IM MH - Humans MH - *Kidney Calculi/surgery MH - *Nephrolithotomy, Percutaneous/methods MH - Hematuria MH - Prospective Studies MH - *Lithotripsy MH - Treatment Outcome MH - *Nephrostomy, Percutaneous EDAT- 2023/05/22 13:04 MHDA- 2023/06/16 06:42 CRDT- 2023/05/22 11:04 PHST- 2022/11/04 00:00 [received] PHST- 2023/02/17 00:00 [accepted] PHST- 2023/06/16 06:42 [medline] PHST- 2023/05/22 13:04 [pubmed] PHST- 2023/05/22 11:04 [entrez] AID - 10.4081/aiua.2023.10991 [doi] PST - epublish SO - Arch Ital Urol Androl. 2023 May 22;95(2):10991. doi: 10.4081/aiua.2023.10991.