PMID- 37219528 OWN - NLM STAT- MEDLINE DCOM- 20230605 LR - 20230607 IS - 1759-9679 (Electronic) IS - 1759-9660 (Linking) VI - 15 IP - 21 DP - 2023 Jun 1 TI - A fast survey on recent developments in designing colorimetric and fluorescent sensors for the selective detection of essential amino acids. PG - 2546-2577 LID - 10.1039/d3ay00155e [doi] AB - Owing to the biological significance of various amino acids, developing accurate and cost-effective sensing techniques for the selective detection of amino acids has recently attracted growing interest. This review discusses the recent advancements of chemosensors in the selective detection of only essential amino acids out of a total of twenty amino acids, which have been applied in chemosensing research, and the mechanism of their action. The focus is directed towards the detection of the most important essential amino acids, like leucine, threonine, lysine, histidine, tryptophan and methionine, since isoleucine and valine are yet to be explored in regard to chemosensing. According to their chemical and fluorescence properties, different sensing techniques, such as the reaction-based approach, DNA-based sensors, nanoparticle formation, coordination ligand binding, host-guest chemistry, the fluorescence indicator displacement (FID) approach, electrochemical sensors, carbon dot-based sensors, MOF-based sensors and metal-based techniques, have been described. FAU - Rao, Nidhi P AU - Rao NP AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. FAU - M, Vaishnavi C AU - M VC AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. FAU - Kumar, Malavika S AU - Kumar MS AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. FAU - S, Vishnu AU - S V AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. FAU - Mukherjee, Bimalendu AU - Mukherjee B AUID- ORCID: 0000-0003-1556-2906 AD - Nano-Biosensors and Biodevices Lab, School of Medical Sciences and Technology, Indian Institute of Technology, Kharagpur, West Bengal, India. FAU - N, Karthik AU - N K AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. FAU - Dutta, Gorachand AU - Dutta G AUID- ORCID: 0000-0003-2980-9826 AD - Nano-Biosensors and Biodevices Lab, School of Medical Sciences and Technology, Indian Institute of Technology, Kharagpur, West Bengal, India. FAU - Das, Avijit Kumar AU - Das AK AUID- ORCID: 0000-0002-3986-1874 AD - Department of Chemistry, CHRIST (Deemed to be University), Hosur Road, Bangalore 560029, Karnataka, India. avijitkumar.das@christuniversity.in. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20230601 PL - England TA - Anal Methods JT - Analytical methods : advancing methods and applications JID - 101519733 RN - 0 (Amino Acids, Essential) RN - 47E5O17Y3R (Phenylalanine) RN - 42HK56048U (Tyrosine) RN - 94ZLA3W45F (Arginine) RN - 0 (Amino Acids) SB - IM MH - *Amino Acids, Essential MH - *Colorimetry MH - Phenylalanine MH - Tyrosine MH - Arginine MH - Amino Acids/metabolism EDAT- 2023/05/23 13:06 MHDA- 2023/06/05 06:43 CRDT- 2023/05/23 10:43 PHST- 2023/06/05 06:43 [medline] PHST- 2023/05/23 13:06 [pubmed] PHST- 2023/05/23 10:43 [entrez] AID - 10.1039/d3ay00155e [doi] PST - epublish SO - Anal Methods. 2023 Jun 1;15(21):2546-2577. doi: 10.1039/d3ay00155e.