PMID- 3723076
OWN - NLM
STAT- MEDLINE
DCOM- 19860729
LR  - 20220216
IS  - 0022-0949 (Print)
IS  - 0022-0949 (Linking)
VI  - 122
DP  - 1986 May
TI  - Cardiovascular responses in the sea raven, Hemitripterus americanus, elicited by 
      vascular compression.
PG  - 65-80
AB  - Increases in the water pressure (PW) around the trunk of the sea raven 
      (Hemitripterus americanus Gmelin) were used to evaluate the effects of vascular 
      compression on cardiovascular variables. Cardiac output (Vb), heart rate (fH) and 
      blood pressures in the ventral aorta, dorsal aorta and ductus Cuvier (Pva, Pda 
      and Pdc, respectively) were measured. A 20 cm H2O increase in PW decreased 
      vascular conductance by up to 25%. During vascular compression, a reflex 
      bradycardia reduced Vb and attenuated the accompanying rise in arterial blood 
      pressure. Pretreatment of the fish with the sympathetic antagonist, propranolol, 
      further attenuated the hypertension by accentuating the reflex bradycardia. 
      Subsequent pretreatment with papaverine, a vascular smooth muscle poison, 
      potentiated these effects and did not reveal any autoregulatory vasodilation in 
      the periphery. Atropine pretreatment completely abolished the reflex bradycardia, 
      indicating that the bradycardia resulted from increased vagal cholinergic tone. 
      The fish also exhibited cardiovascular compensation during the 2 min vascular 
      compression. An accommodation of the barostatic reflex (reduced vagal tone) and a 
      sympathetic tachycardia raised Vb and passively increased vascular conductance. 
      The set point for the barostatic bradycardia was apparently 
      temperature-sensitive.
FAU - Farrell, A P
AU  - Farrell AP
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Exp Biol
JT  - The Journal of experimental biology
JID - 0243705
RN  - 9Y8NXQ24VQ (Propranolol)
RN  - DAA13NKG2Q (Papaverine)
SB  - IM
MH  - Animals
MH  - Arteries/physiology
MH  - Blood Pressure
MH  - Cardiac Output
MH  - *Cardiovascular Physiological Phenomena
MH  - Electric Conductivity
MH  - Fishes/*physiology
MH  - Heart Rate/drug effects
MH  - Papaverine/pharmacology
MH  - Pressure
MH  - Propranolol/pharmacology
MH  - Vasodilation/drug effects
EDAT- 1986/05/01 00:00
MHDA- 1986/05/01 00:01
CRDT- 1986/05/01 00:00
PHST- 1986/05/01 00:00 [pubmed]
PHST- 1986/05/01 00:01 [medline]
PHST- 1986/05/01 00:00 [entrez]
AID - 10.1242/jeb.122.1.65 [doi]
PST - ppublish
SO  - J Exp Biol. 1986 May;122:65-80. doi: 10.1242/jeb.122.1.65.