PMID- 37233658
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230530
IS  - 2218-1989 (Print)
IS  - 2218-1989 (Electronic)
IS  - 2218-1989 (Linking)
VI  - 13
IP  - 5
DP  - 2023 Apr 30
TI  - The Impact of Metabolic Syndrome Components on Erectile Function in Patients with 
      Type 2 Diabetes.
LID - 10.3390/metabo13050617 [doi]
LID - 617
AB  - Erectile dysfunction is commonly encountered in diabetic patients and in patients 
      with metabolic syndrome; however, only a few studies have assessed patients with 
      metabolic syndrome and type 2 diabetes mellitus (T2DM) regarding their sexual 
      function. The purpose of this study is to examine the effect of metabolic 
      syndrome and its components on the erectile function of T2DM patients. A 
      cross-sectional study including T2DM patients was conducted from November 2018 
      until November 2020. Participants were evaluated for the presence of metabolic 
      syndrome and their sexual function was assessed using the International Index of 
      Erectile Function (IIEF) questionnaire. A total of 45 consecutive male patients 
      participated in this study. Metabolic syndrome was diagnosed in 84.4% and 
      erectile dysfunction (ED) in 86.7% of them. Metabolic syndrome was not associated 
      with ED or ED severity. Among metabolic syndrome components, only high-density 
      lipoprotein cholesterol (HDL) was associated with ED [x(2) (1, n = 45) = 3.894, p 
      = 0.048; OR = 5.5 (95% CI: 0.890-33.99)] and with the IIEF erectile function 
      scores (median 23 vs. 18, U = 75, p = 0.012). Multiple regression analyses showed 
      that HDL was non-significantly associated with the IIEF erectile function scores. 
      In conclusion, among T2DM patients HDL is associated with ED.
FAU - Katsimardou, Alexandra
AU  - Katsimardou A
AUID- ORCID: 0000-0002-9180-6071
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Patoulias, Dimitrios
AU  - Patoulias D
AUID- ORCID: 0000-0002-6899-684X
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Zografou, Ioanna
AU  - Zografou I
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Siskos, Fotios
AU  - Siskos F
AUID- ORCID: 0000-0002-4362-2219
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Stavropoulos, Konstantinos
AU  - Stavropoulos K
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Imprialos, Konstantinos
AU  - Imprialos K
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Tegou, Zoi
AU  - Tegou Z
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Boulmpou, Aristi
AU  - Boulmpou A
AUID- ORCID: 0000-0002-5008-114X
AD  - 3rd Department of Cardiology, Aristotle University of Thessaloniki, Hippokration 
      General Hospital, 54642 Thessaloniki, Greece.
FAU - Georgopoulou, Vivian
AU  - Georgopoulou V
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Hatzipapa, Nikoleta
AU  - Hatzipapa N
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
FAU - Papadopoulos, Christodoulos
AU  - Papadopoulos C
AUID- ORCID: 0000-0001-9643-9066
AD  - 3rd Department of Cardiology, Aristotle University of Thessaloniki, Hippokration 
      General Hospital, 54642 Thessaloniki, Greece.
FAU - Doumas, Michael
AU  - Doumas M
AD  - 2nd Propedeutic Department of Internal Medicine, Aristotle University of 
      Thessaloniki, Hippokration General Hospital, 54642 Thessaloniki, Greece.
AD  - Veterans Affairs Medical Center, George Washington University, Washington, DC 
      20422, USA.
LA  - eng
PT  - Journal Article
DEP - 20230430
PL  - Switzerland
TA  - Metabolites
JT  - Metabolites
JID - 101578790
PMC - PMC10222854
OTO - NOTNLM
OT  - HDL
OT  - erectile dysfunction
OT  - hypertension
OT  - metabolic syndrome
OT  - obesity
OT  - sexual dysfunction
OT  - triglycerides
OT  - type 2 diabetes mellitus
COIS- The authors declare no conflict of interest.
EDAT- 2023/05/26 13:09
MHDA- 2023/05/26 13:10
PMCR- 2023/04/30
CRDT- 2023/05/26 10:33
PHST- 2023/03/15 00:00 [received]
PHST- 2023/03/31 00:00 [revised]
PHST- 2023/04/28 00:00 [accepted]
PHST- 2023/05/26 13:10 [medline]
PHST- 2023/05/26 13:09 [pubmed]
PHST- 2023/05/26 10:33 [entrez]
PHST- 2023/04/30 00:00 [pmc-release]
AID - metabo13050617 [pii]
AID - metabolites-13-00617 [pii]
AID - 10.3390/metabo13050617 [doi]
PST - epublish
SO  - Metabolites. 2023 Apr 30;13(5):617. doi: 10.3390/metabo13050617.