PMID- 37234595 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230529 IS - 2590-1362 (Electronic) IS - 2590-1362 (Linking) VI - 14 DP - 2023 Aug TI - Vaccination inequities among children 12-23 months in India: An analysis of inter-state differences. PG - 100310 LID - 10.1016/j.jvacx.2023.100310 [doi] LID - 100310 AB - BACKGROUND: Previous research has shown that socioeconomic and demographic risk factors in children are additive and lead to increasingly negative impacts on vaccination coverage. The goal of this study is to examine if different combinations of four risk factors (infant sex, birth order, maternal education level, and family wealth status) vary by state among children 12-23 months in India and to determine the impact of >/= 1 risk factor on differences in state vaccination rates. METHODS: Using data from the National Family Health Survey (NFHS) conducted in India between 2005 and 2006 (NFHS-3) and 2015-2016 (NFHS-4), full vaccination of children 12-23 months was examined. Full vaccination was defined as receipt of one dose of bacillus Calmette-Guerin (BCG), three doses of diphtheria-pertussis-tetanus vaccine (DPT) vaccine, three doses of oral polio vaccine (OPV), and one dose of measles-containing vaccine (MCV). Associations between full vaccination and the four risk factors were assessed using logistic regression. Data were analyzed by the state of residence. RESULTS: A total of 60.9% of children 12-23 months were fully vaccinated, in NFHS-4, ranging from 33.9% in Arunachal Pradesh to 91.3% in Punjab. In NFHS-4, the odds of full vaccination across all states were 15% lower among infants with 2 risk factors versus 0 or 1 risk factors (OR: 0.85, 95% CI: 0.80-0.91), and 28% lower among infants with 3 or 4 risk factors versus 0 or 1 risk factor (OR: 0.72, 95% CI: 0.67-0.78). Overall, the absolute difference in the full vaccination coverage in those with > 2 vs < 2 risk factors decreased from -13% in NFHS-3 to -5.6% in NFHS-4, with substantial variation across states. CONCLUSIONS: Disparities in full vaccination exist among children 12-23 months experiencing > 1 risk factor. Indian states that are more populous or located in the north were more likely to have greater disparities. CI - (c) 2023 The Author(s). FAU - Goodman, Octavia K AU - Goodman OK AD - College of Health Sciences, Old Dominion University, 5115 Terminal Blvd, Norfolk, VA 23529, USA. FAU - Wagner, Abram L AU - Wagner AL AD - Department of Epidemiology, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA. FAU - Riopelle, Dakota AU - Riopelle D AD - Department of Epidemiology, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA. FAU - Mathew, Joseph L AU - Mathew JL AD - PGIMER, QQ7G+JC4, P.G.I, Sector 12, Chandigarh 160012, India. FAU - Boulton, Matthew L AU - Boulton ML AD - Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA. AD - Department of Internal Medicine, Infectious Diseases Division, Michigan Medicine, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA. LA - eng PT - Journal Article DEP - 20230505 PL - England TA - Vaccine X JT - Vaccine: X JID - 101748769 PMC - PMC10205789 OTO - NOTNLM OT - Disparities OT - India OT - Infants OT - Risk factors OT - Vaccination COIS- The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Matthew L. Boulton reports financial support was provided by National Institute on Minority Health and Health Disparities of the National Institutes of Health. EDAT- 2023/05/26 19:14 MHDA- 2023/05/26 19:15 PMCR- 2023/05/05 CRDT- 2023/05/26 12:13 PHST- 2022/09/08 00:00 [received] PHST- 2023/04/15 00:00 [revised] PHST- 2023/04/30 00:00 [accepted] PHST- 2023/05/26 19:15 [medline] PHST- 2023/05/26 19:14 [pubmed] PHST- 2023/05/26 12:13 [entrez] PHST- 2023/05/05 00:00 [pmc-release] AID - S2590-1362(23)00051-7 [pii] AID - 100310 [pii] AID - 10.1016/j.jvacx.2023.100310 [doi] PST - epublish SO - Vaccine X. 2023 May 5;14:100310. doi: 10.1016/j.jvacx.2023.100310. eCollection 2023 Aug.