PMID- 37235194
OWN - NLM
STAT- MEDLINE
DCOM- 20230529
LR  - 20240302
IS  - 1945-5763 (Electronic)
IS  - 1082-0744 (Print)
IS  - 1082-0744 (Linking)
VI  - 29
IP  - 2
DP  - 2023 Spring
TI  - A Secondary Analysis of Short- and Long-Term Variability of Inspiratory Muscle 
      Performance in People Living With SCI.
PG  - 97-106
LID - 10.46292/sci22-00027 [doi]
AB  - OBJECTIVES: To explore the expected variability in repeated short-term (ST) and 
      long-term (LT) inspiratory muscle performance (IMP) in individuals with chronic 
      spinal cord injury (SCI). METHODS: Maximal inspiratory pressure (MIP), sustained 
      MIP (SMIP), and inspiratory duration (ID) were collected from 22 individuals with 
      chronic SCI (C1-T9, American Spinal Injury Association Impairment Scale [AIS] 
      A-C) over 18 months. ST data were collected four times within 2 weeks (n = 19). 
      LT data were collected at two time points at least 7 months apart (n = 20). 
      RESULTS: SMIP was the most reliable IMP assessment with an intraclass correlation 
      coefficient (ICC) of 0.959, followed by MIP (ICC 0.874) and ID (ICC 0.689). The 
      ID was the only ST measure to have a significant difference [MIP: F(3, 54) = 2.5, 
      p = .07; SMIP: F(3, 54) = 1.3, p = .29; ID: F(1.4, 25.6) = 4.8, p = .03]. Post 
      hoc analysis showed the mean day 1 ST ID measure was significantly different from 
      both days 3 and 4. The percent change of ID from day 3 to day 6 was 11.6%. No LT 
      measures differed significantly [mean change (SD) [95% CI] for MIP: 5.2 cm H(2)O 
      (18.8) [-3.6, 13.9], p = .235; SMIP: 60.9 pressure time unit (166.1) [-16.9, 
      138.6], p = .118; ID: 0.1 s (2.5) [-1.1, 1.3], p = .855]. CONCLUSION: These data 
      provide a foundation for understanding normal variance in ST and LT IMP in the 
      SCI population. Change in MIP function outside 10% is likely a true and 
      meaningful change and may help clinicians recognize individuals with SCI at risk 
      for respiratory compromise. Future studies should explore changes in MIP and SMIP 
      that are associated with meaningful functional changes.
CI  - (c)2023 American Spinal Injury Association.
FAU - Palermo, Anne E
AU  - Palermo AE
AD  - Neuroscience Research Australia (NeuRA), Sydney, Australia.
AD  - University of New South Wales, Sydney Australia.
FAU - Cahalin, Lawrence P
AU  - Cahalin LP
AD  - Department of Physical Therapy, University of Miami, Miami, Florida.
FAU - Nash, Mark S
AU  - Nash MS
AD  - The Miami Project to Cure Paralysis, University of Miami, Miami, Florida.
LA  - eng
PT  - Journal Article
DEP - 20230203
PL  - United States
TA  - Top Spinal Cord Inj Rehabil
JT  - Topics in spinal cord injury rehabilitation
JID - 9515174
SB  - IM
MH  - Humans
MH  - *Spinal Cord Injuries/complications
MH  - Muscles
PMC - PMC10208253
OTO - NOTNLM
OT  - maximum inspiratory pressure
OT  - respiration
OT  - respiratory function tests
OT  - spinal cord injuries
OT  - sustained maximum inspiratory pressure
COIS- Conflicts of Interest The authors report no conflicts of interest.
EDAT- 2023/05/26 19:15
MHDA- 2023/05/29 06:42
PMCR- 2024/03/01
CRDT- 2023/05/26 12:24
PHST- 2023/05/29 06:42 [medline]
PHST- 2023/05/26 19:15 [pubmed]
PHST- 2023/05/26 12:24 [entrez]
PHST- 2024/03/01 00:00 [pmc-release]
AID - 10.46292/sci22-00027 [doi]
PST - ppublish
SO  - Top Spinal Cord Inj Rehabil. 2023 Spring;29(2):97-106. doi: 10.46292/sci22-00027. 
      Epub 2023 Feb 3.