PMID- 37241216
OWN - NLM
STAT- MEDLINE
DCOM- 20230529
LR  - 20230530
IS  - 1648-9144 (Electronic)
IS  - 1010-660X (Print)
IS  - 1010-660X (Linking)
VI  - 59
IP  - 5
DP  - 2023 May 19
TI  - Remission of Type 2 Diabetes Mellitus (T2DM) after Sleeve Gastrectomy (SG), 
      One-Anastomosis Gastric Bypass (OAGB), and Roux-en-Y Gastric Bypass (RYGB): A 
      Systematic Review.
LID - 10.3390/medicina59050985 [doi]
LID - 985
AB  - Background and Objectives: The three most widely performed bariatric surgeries 
      are Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy (SG), and one-anastomosis 
      gastric bypass (OAGB). Aside from the benefits of weight loss, current findings 
      suggest that these procedures can also induce remission of T2DM (type 2 diabetes 
      mellitus). There are limited data that directly compare these three procedures. 
      This study aims to compare the short-term and long-term remission of T2DM after 
      RYGB, SG, and OAGB. Materials and Methods: Three databases (Embase, PubMed, and 
      Cochrane) were searched for randomised controlled trials, prospective studies, 
      and retrospective studies that compared the effects of RYGB, SG, and OAGB on T2DM 
      remission. Studies published between 2001 and 2022 were analysed. Only patients 
      with T2DM and who had primary bariatric surgery were included. Results: After 
      applying the inclusion and exclusion criteria, seven articles were included in 
      the review. It was found that all three procedures had comparable T2DM remission. 
      RYGB was noted to have the highest complication rate when compared to SG and 
      OAGB. Importantly, it was noted that other predictive factors such as age, 
      duration of diabetes, baseline HbA1c, BMI, and use of antidiabetic medication 
      play a crucial role in T2DM remission. Conclusions: This systematic literature 
      review confirms the existing data that all three bariatric surgeries induce 
      remission of T2DM. Increasing in popularity, OAGB had comparable outcomes to RYGB 
      and SG in inducing T2DM remission. In addition to the choice of bariatric 
      surgery, there are other independent predictive factors that have an impact on 
      T2DM remission. Further studies with larger sample sizes, longer follow-up 
      periods, and studies that control confounding factors are required in this field.
FAU - Balasubaramaniam, Vignesh
AU  - Balasubaramaniam V
AD  - Department of General Surgery, Ysbyty Gwynedd Hospital, Bangor LL57 2FA, UK.
FAU - Pouwels, Sjaak
AU  - Pouwels S
AUID- ORCID: 0000-0002-6390-7692
AD  - Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, P.O. Box 
      9051, 5000 LC Tilburg, The Netherlands.
AD  - Department of General, Abdominal and Minimally Invasive Surgery, Helios Klinikum, 
      Lutherplatz 40, 47805 Krefeld, Germany.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20230519
PL  - Switzerland
TA  - Medicina (Kaunas)
JT  - Medicina (Kaunas, Lithuania)
JID - 9425208
SB  - IM
MH  - Humans
MH  - *Gastric Bypass/methods
MH  - *Obesity, Morbid/complications/surgery
MH  - *Diabetes Mellitus, Type 2/complications/surgery
MH  - Retrospective Studies
MH  - Prospective Studies
MH  - Gastrectomy/methods
MH  - Treatment Outcome
PMC - PMC10222088
OTO - NOTNLM
OT  - Roux-en-Y gastric bypass
OT  - diabetes remission
OT  - one-anastomosis gastric bypass
OT  - sleeve gastrectomy
OT  - type 2 diabetes mellitus
COIS- The authors declare no conflict of interest.
EDAT- 2023/05/27 09:42
MHDA- 2023/05/29 06:42
PMCR- 2023/05/19
CRDT- 2023/05/27 01:21
PHST- 2023/03/09 00:00 [received]
PHST- 2023/05/06 00:00 [revised]
PHST- 2023/05/11 00:00 [accepted]
PHST- 2023/05/29 06:42 [medline]
PHST- 2023/05/27 09:42 [pubmed]
PHST- 2023/05/27 01:21 [entrez]
PHST- 2023/05/19 00:00 [pmc-release]
AID - medicina59050985 [pii]
AID - medicina-59-00985 [pii]
AID - 10.3390/medicina59050985 [doi]
PST - epublish
SO  - Medicina (Kaunas). 2023 May 19;59(5):985. doi: 10.3390/medicina59050985.