PMID- 37245878
OWN - NLM
STAT- MEDLINE
DCOM- 20230530
LR  - 20240330
IS  - 1558-5034 (Electronic)
IS  - 0887-2171 (Linking)
VI  - 44
IP  - 3
DP  - 2023 Jun
TI  - Diffusion and Perfusion Imaging in Rectal Cancer Restaging.
PG  - 117-125
LID - S0887-2171(23)00016-1 [pii]
LID - 10.1053/j.sult.2023.02.002 [doi]
AB  - The assessment of tumor response, after neoadjuvant radiochemotherapy (n-CRT), 
      permits the stratification of patients for the proper therapeutical management. 
      Although histopathology analysis of the surgical speciemen is considered the gold 
      standard for assessing tumor response, magnetic resonance imaging (MRI), with its 
      significant developments in technical imaging, have allowed an increase in 
      accuracy for the evaluation of response. MRI provides a radiological tumor 
      regression grade (mrTRG) that is correlated with the pathologic tumor regression 
      grade (pTRG). Functional MRI parameters have additional impending in early 
      prediction of the efficacy of therapy. Some of functional methodologies are 
      already part of clinical practice: diffusion-weighted MRI (DW-MRI) and perfusion 
      imaging (dynamic contrast enhanced MRI [DCE-MRI]).
CI  - Copyright (c) 2023. Published by Elsevier Inc.
FAU - Granata, Vincenza
AU  - Granata V
AD  - Division of Radiology, "Istituto Nazionale Tumori IRCCS Fondazione Pascale - 
      IRCCS di Napoli", Naples, Italy.
FAU - Fusco, Roberta
AU  - Fusco R
AD  - Medical Oncology Division, Igea SpA, Napoli, Italy. Electronic address: 
      r.fusco@igeamedical.com.
FAU - Setola, Sergio Venazio
AU  - Setola SV
AD  - Division of Radiology, "Istituto Nazionale Tumori IRCCS Fondazione Pascale - 
      IRCCS di Napoli", Naples, Italy.
FAU - Cozzi, Diletta
AU  - Cozzi D
AD  - Department of Radiology, Azienda Ospedaliero-Universitaria Careggi, Florence, 
      Italy; Italian Society of Medical and Interventional Radiology (SIRM), SIRM 
      Foundation, Milan, Italy.
FAU - Rega, Daniela
AU  - Rega D
AD  - Division of Gastrointestinal Surgical Oncology, "Istituto Nazionale Tumori - 
      IRCCS - Fondazione G. Pascale", Naples, Italy.
FAU - Petrillo, Antonella
AU  - Petrillo A
AD  - Division of Radiology, "Istituto Nazionale Tumori IRCCS Fondazione Pascale - 
      IRCCS di Napoli", Naples, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230303
PL  - United States
TA  - Semin Ultrasound CT MR
JT  - Seminars in ultrasound, CT, and MR
JID - 8504689
SB  - IM
MH  - Humans
MH  - Perfusion Imaging
MH  - *Diffusion Magnetic Resonance Imaging
MH  - *Rectal Neoplasms/diagnostic imaging/pathology/therapy
MH  - Neoplasm Staging
MH  - *Neoadjuvant Therapy/methods
EDAT- 2023/05/29 00:42
MHDA- 2023/05/30 06:42
CRDT- 2023/05/28 20:56
PHST- 2023/05/30 06:42 [medline]
PHST- 2023/05/29 00:42 [pubmed]
PHST- 2023/05/28 20:56 [entrez]
AID - S0887-2171(23)00016-1 [pii]
AID - 10.1053/j.sult.2023.02.002 [doi]
PST - ppublish
SO  - Semin Ultrasound CT MR. 2023 Jun;44(3):117-125. doi: 10.1053/j.sult.2023.02.002. 
      Epub 2023 Mar 3.