PMID- 37258171
OWN - NLM
STAT- MEDLINE
DCOM- 20240116
LR  - 20240215
IS  - 1349-7235 (Electronic)
IS  - 0918-2918 (Print)
IS  - 0918-2918 (Linking)
VI  - 63
IP  - 2
DP  - 2024 Jan 15
TI  - Left Main Bronchus Obstruction in a Patient with Small-cell Lung Cancer 
      Successfully Treated with Venovenous Extracorporeal Membrane Oxygenation.
PG  - 293-298
LID - 10.2169/internalmedicine.1005-22 [doi]
AB  - Lung cancer can cause fatal central airway obstruction. Rapid airway clearance is 
      necessary in some cases, but ventilator management may be insufficient to 
      maintain oxygenation levels. Venovenous extracorporeal membrane oxygenation 
      (VV-ECMO) may be an effective rescue therapy for respiratory failure, but its 
      efficacy in treating tumor-related airway obstruction is unknown. We herein 
      report a case of central airway obstruction and severe acute respiratory failure 
      due to small-cell lung cancer successfully treated with VV-ECMO, bronchoscopic 
      airway intervention, and chemotherapy. VV-ECMO can be an effective option for the 
      treatment of central airway obstruction with acute respiratory failure due to 
      lung cancer.
FAU - Nagai, Tatsuya
AU  - Nagai T
AD  - Department of Pulmonology, Kameda Medical Center, Japan.
FAU - Yoshida, Kyoko
AU  - Yoshida K
AD  - Department of Pulmonology, Kameda Medical Center, Japan.
FAU - Otsuki, Ayumu
AU  - Otsuki A
AD  - Department of Pulmonology, Kameda Medical Center, Japan.
FAU - So, Yuko
AU  - So Y
AD  - Department of Intensive Care Medicine, Kameda Medical Center, Japan.
FAU - Karumai, Toshiyuki
AU  - Karumai T
AD  - Department of Intensive Care Medicine, Kameda Medical Center, Japan.
FAU - Sugimura, Hiroshi
AU  - Sugimura H
AD  - Department of Thoracic Surgery, Kameda Medical Center, Japan.
FAU - Tachibana, Yuri
AU  - Tachibana Y
AD  - Department of Clinical Pathology, Kameda Medical Center, Japan.
FAU - Fukuoka, Junya
AU  - Fukuoka J
AD  - Department of Clinical Pathology, Kameda Medical Center, Japan.
FAU - Ito, Hiroyuki
AU  - Ito H
AD  - Department of Pulmonology, Kameda Medical Center, Japan.
FAU - Nakashima, Kei
AU  - Nakashima K
AD  - Department of Pulmonology, Kameda Medical Center, Japan.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20230531
PL  - Japan
TA  - Intern Med
JT  - Internal medicine (Tokyo, Japan)
JID - 9204241
SB  - IM
MH  - Humans
MH  - *Extracorporeal Membrane Oxygenation
MH  - *Lung Neoplasms/complications/therapy
MH  - *Respiratory Insufficiency/etiology/therapy
MH  - *Airway Obstruction/therapy/complications
MH  - *Respiratory Distress Syndrome
MH  - *Small Cell Lung Carcinoma/complications/therapy
MH  - Bronchi
PMC - PMC10864078
OTO - NOTNLM
OT  - airway obstruction
OT  - bronchoscopic surgery
OT  - extracorporeal membrane oxygenation
OT  - lung cancer
OT  - respiratory failure
COIS- The authors state that they have no Conflict of Interest (COI).
EDAT- 2023/06/01 01:08
MHDA- 2024/01/16 06:42
PMCR- 2024/01/15
CRDT- 2023/05/31 21:38
PHST- 2024/01/16 06:42 [medline]
PHST- 2023/06/01 01:08 [pubmed]
PHST- 2023/05/31 21:38 [entrez]
PHST- 2024/01/15 00:00 [pmc-release]
AID - 10.2169/internalmedicine.1005-22 [doi]
PST - ppublish
SO  - Intern Med. 2024 Jan 15;63(2):293-298. doi: 10.2169/internalmedicine.1005-22. 
      Epub 2023 May 31.