PMID- 37261367 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230604 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 15 IP - 5 DP - 2023 May TI - Noninvasive Calculation of Cerebrospinal Fluid Production Using Phase-Contrast Magnetic Resonance Imaging: First Implementation in Augusta, Georgia. PG - e39686 LID - 10.7759/cureus.39686 [doi] LID - e39686 AB - This retrospective review examines the utility of phase-contrast magnetic resonance imaging (PC-MRI) to calculate flow through the aqueduct between the third and fourth ventricles to estimate cerebrospinal fluid (CSF) production. Imaging software quantified the CSF flow rate across the aqueduct of four females and two males at a single center, and the mean of these results was compared to the established mean CSF production calculated by invasive techniques. There was no significant difference between the means, contributing to the body of literature suggesting the utility of PC-MRI in estimating CSF production rates. CI - Copyright (c) 2023, Oliver et al. FAU - Oliver, Tucker AU - Oliver T AD - Neurological Surgery, Augusta University Medical College of Georgia, Augusta, USA. FAU - Macomson, Samuel AU - Macomson S AD - Neurological Surgery, Augusta University Medical College of Georgia, Augusta, USA. FAU - Gilbert, Bruce AU - Gilbert B AD - Radiology, Augusta University Medical College of Georgia, Augusta, USA. FAU - Forseen, Scott AU - Forseen S AD - Radiology, Augusta University Medical College of Georgia, Augusta, USA. LA - eng PT - Journal Article DEP - 20230530 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC10227773 OTO - NOTNLM OT - aqueduct OT - cerebrospinal fluid OT - csf OT - noninvasive OT - phase-contrast mri OT - production COIS- The authors have declared that no competing interests exist. EDAT- 2023/06/01 13:10 MHDA- 2023/06/01 13:11 PMCR- 2023/05/30 CRDT- 2023/06/01 10:40 PHST- 2023/05/27 00:00 [accepted] PHST- 2023/06/01 13:11 [medline] PHST- 2023/06/01 13:10 [pubmed] PHST- 2023/06/01 10:40 [entrez] PHST- 2023/05/30 00:00 [pmc-release] AID - 10.7759/cureus.39686 [doi] PST - epublish SO - Cureus. 2023 May 30;15(5):e39686. doi: 10.7759/cureus.39686. eCollection 2023 May.