PMID- 37262285
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20230604
LR  - 20230604
IS  - 1539-4794 (Electronic)
IS  - 0146-9592 (Linking)
VI  - 48
IP  - 11
DP  - 2023 Jun 1
TI  - Thermally tuned VCSEL at 850 nm as a low-cost alternative source for full-eye 
      SS-OCT.
PG  - 3079-3082
LID - 10.1364/OL.489050 [doi]
AB  - Swept-source optical coherence tomography (SS-OCT) demonstrates superior 
      performance in comparison to spectral domain OCT with regard to depth ranging. 
      The main driver of cost for SS-OCT systems is, however, the price of the source. 
      Here we show a low-cost alternative swept source that uses a thermally tuned 
      vertical-cavity surface-emitting laser (VCSEL) at 850 nm. Its center wavelength 
      can be tuned by adjusting the operating temperature through modulation of the 
      injection current. At 2 kHz sweep rate, the depth range of the system was 5 cm, 
      with a sensitivity roll-off of under -3 dB across this range. The system achieved 
      a sensitivity of 97 dB with a sample beam power of 0.3 mW and an axial resolution 
      of 50 microm in air. To demonstrate the system performance in vivo, an eye of a 
      healthy volunteer was measured, and full-eye scans were acquired at 25 and 50 kHz 
      from the cornea to the retina. Based on our results, we believe that this 
      technology can be used as a cost-effective alternative OCT for point-of-care 
      diagnostics.
FAU - Kendrisic, Milana
AU  - Kendrisic M
FAU - Agafonov, Vladislav
AU  - Agafonov V
FAU - Salas, Matthias
AU  - Salas M
FAU - Ferrara, Lorenzo
AU  - Ferrara L
FAU - Niederleithner, Michael
AU  - Niederleithner M
FAU - Resch, Hemma
AU  - Resch H
FAU - Steiner, Stefan
AU  - Steiner S
FAU - Vass, Clemens
AU  - Vass C
FAU - Drexler, Wolfgang
AU  - Drexler W
FAU - Leitgeb, Rainer A
AU  - Leitgeb RA
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Opt Lett
JT  - Optics letters
JID - 7708433
SB  - IM
EDAT- 2023/06/01 23:42
MHDA- 2023/06/01 23:43
CRDT- 2023/06/01 14:23
PHST- 2023/06/01 23:43 [medline]
PHST- 2023/06/01 23:42 [pubmed]
PHST- 2023/06/01 14:23 [entrez]
AID - 531155 [pii]
AID - 10.1364/OL.489050 [doi]
PST - ppublish
SO  - Opt Lett. 2023 Jun 1;48(11):3079-3082. doi: 10.1364/OL.489050.