PMID- 37265973
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230604
IS  - 1311-0160 (Print)
IS  - 2199-5761 (Electronic)
IS  - 1311-0160 (Linking)
VI  - 25
IP  - 2
DP  - 2023 May
TI  - Unusual Manifestation of Extraosseous Ewing Sarcoma: Report of 3 Cases.
PG  - 77-81
LID - 10.2478/bjmg-2022-0022 [doi]
AB  - Ewing sarcoma (ES), described as a diffuse endothelioma of the bone, is divided 
      into two categories: osseous and extraosseous, which mainly affects adolescents. 
      Extraosseous Ewing Sarcomas (EES) are rare tumors originating from soft tissues. 
      Their clinical presentation depends mainly on the primary location of the tumor 
      and are highly chemosensitive and radiosensitive. The purpose of this study was 
      to describe the clinical characteristics and outcomes of 3 children with EES and 
      uncommon presentation treated in our Unit. The diagnosis of EES was confirmed by 
      biopsy and cytogenetic analysis with fluorescence in situ hybridization (FISH). 
      Surgical excision was planned as primary treatment, followed by adjuvant 
      chemotherapy according to EURO-E.W.I.N.G protocol. To date, all patients are 
      alive, 1, 3 and 4 years after completion of treatment, with no signs of 
      recurrence or metastasis.
CI  - (c) 2022 Ioannidou M. et al., published by Sciendo.
FAU - Ioannidou, M
AU  - Ioannidou M
AD  - Children's and Adolescent's Hematology-Oncology Unit of 2nd Department of 
      Pediatrics, Aristotle University of Thessaloniki, AHEPA University General 
      Hospital, Thessaloniki, Greece.
FAU - Tsotridou, E
AU  - Tsotridou E
AD  - Children's and Adolescent's Hematology-Oncology Unit of 2nd Department of 
      Pediatrics, Aristotle University of Thessaloniki, AHEPA University General 
      Hospital, Thessaloniki, Greece.
FAU - Samoladas, E
AU  - Samoladas E
AD  - 2nd Department of Orthopedic Surgery, Aristotle University of Thessaloniki, 
      "Gennimatas" General Hospital, Thessaloniki, Greece.
FAU - Tragiannidis, A
AU  - Tragiannidis A
AD  - Children's and Adolescent's Hematology-Oncology Unit of 2nd Department of 
      Pediatrics, Aristotle University of Thessaloniki, AHEPA University General 
      Hospital, Thessaloniki, Greece.
FAU - Kouskouras, K
AU  - Kouskouras K
AD  - Department of Radiology, Aristotle University of Thessaloniki, AHEPA University 
      General Hospital, Thessaloniki, Greece.
FAU - Sfougaris, D
AU  - Sfougaris D
AD  - 1st Department of Pediatric Surgery, Aristotle University of Thessaloniki, 
      "Gennimatas" General Hospital, Thessaloniki, Greece.
FAU - Spyridakis, I
AU  - Spyridakis I
AD  - 2nd Department of Pediatric Surgery, Aristotle University of Thessaloniki, 
      "Papageorgiou" General Hospital, Thessaloniki, Greece.
FAU - Foroulis, C
AU  - Foroulis C
AD  - Department of Cardiothoracic Surgery, Aristotle University of Thessaloniki, AHEPA 
      University General Hospital, Thessaloniki, Greece.
FAU - Galli-Tsinopoulou, A
AU  - Galli-Tsinopoulou A
AD  - Children's and Adolescent's Hematology-Oncology Unit of 2nd Department of 
      Pediatrics, Aristotle University of Thessaloniki, AHEPA University General 
      Hospital, Thessaloniki, Greece.
FAU - Hatzipantelis, E
AU  - Hatzipantelis E
AD  - Children's and Adolescent's Hematology-Oncology Unit of 2nd Department of 
      Pediatrics, Aristotle University of Thessaloniki, AHEPA University General 
      Hospital, Thessaloniki, Greece.
LA  - eng
PT  - Journal Article
DEP - 20230502
PL  - Poland
TA  - Balkan J Med Genet
JT  - Balkan journal of medical genetics : BJMG
JID - 9806959
PMC - PMC10230840
OTO - NOTNLM
OT  - cytogenetics
OT  - extraosseous Ewing sarcoma
OT  - surgical resection
COIS- Declaration of interest: The authors report no conflicts of interest. The authors 
      alone are responsible for the content and writing of this article.
EDAT- 2023/06/02 13:16
MHDA- 2023/06/02 13:17
PMCR- 2023/05/02
CRDT- 2023/06/02 10:52
PHST- 2023/06/02 13:17 [medline]
PHST- 2023/06/02 13:16 [pubmed]
PHST- 2023/06/02 10:52 [entrez]
PHST- 2023/05/02 00:00 [pmc-release]
AID - bjmg-2022-0022 [pii]
AID - 10.2478/bjmg-2022-0022 [doi]
PST - epublish
SO  - Balkan J Med Genet. 2023 May 2;25(2):77-81. doi: 10.2478/bjmg-2022-0022. 
      eCollection 2023 May.