PMID- 37292481 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240328 IS - 2331-8422 (Electronic) IS - 2331-8422 (Linking) DP - 2024 Mar 8 TI - The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs). LID - arXiv:2305.17033v6 AB - Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. The MICCAI Brain Tumor Segmentation (BraTS) Challenge is a landmark community benchmark event with a successful history of 12 years of resource creation for the segmentation and analysis of adult glioma. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge, which represents the first BraTS challenge focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The BraTS-PEDs 2023 challenge focuses on benchmarking the development of volumentric segmentation algorithms for pediatric brain glioma through standardized quantitative performance evaluation metrics utilized across the BraTS 2023 cluster of challenges. Models gaining knowledge from the BraTS-PEDs multi-parametric structural MRI (mpMRI) training data will be evaluated on separate validation and unseen test mpMRI dataof high-grade pediatric glioma. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors. FAU - Kazerooni, Anahita Fathi AU - Kazerooni AF AUID- ORCID: 0000-0001-7131-2261 AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA. AD - Center for AI & Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA. FAU - Khalili, Nastaran AU - Khalili N AUID- ORCID: 0000-0001-8078-3591 AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Liu, Xinyang AU - Liu X AD - Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington DC, USA. FAU - Haldar, Debanjan AU - Haldar D AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Department of Neurosurgery, Thomas Jefferson University Hospital, PA, USA. FAU - Jiang, Zhifan AU - Jiang Z AD - Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington DC, USA. FAU - Anwar, Syed Muhammed AU - Anwar SM AD - Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington DC, USA. FAU - Albrecht, Jake AU - Albrecht J AD - Sage Bionetworks, USA. FAU - Adewole, Maruf AU - Adewole M AD - Medical Artificial Intelligence (MAI) Lab, Crestview Radiology, Lagos, Nigeria. FAU - Anazodo, Udunna AU - Anazodo U AD - Montreal Neurological Institute (MNI), McGill University, Montreal, QC, Canada. FAU - Anderson, Hannah AU - Anderson H AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Bagheri, Sina AU - Bagheri S AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Baid, Ujjwal AU - Baid U AUID- ORCID: 0000-0001-5246-2088 AD - Center for AI & Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA. AD - Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. AD - Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. FAU - Bergquist, Timothy AU - Bergquist T AD - Sage Bionetworks, USA. FAU - Borja, Austin J AU - Borja AJ AD - Department of Neurosurgery at the University of Southern California, CA, USA. FAU - Calabrese, Evan AU - Calabrese E AD - Department of Radiology, Duke University Medical Center, USA. FAU - Chung, Verena AU - Chung V AD - Sage Bionetworks, USA. FAU - Conte, Gian-Marco AU - Conte GM AD - Mayo Clinic, MN, USA. FAU - Dako, Farouk AU - Dako F AD - Center for Global Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. FAU - Eddy, James AU - Eddy J AD - Sage Bionetworks, USA. FAU - Ezhov, Ivan AU - Ezhov I AD - Department of Informatics, Technical University Munich, Germany. AD - TranslaTUM - Central Institute for Translational Cancer Research, Technical University of Munich, Germany. FAU - Familiar, Ariana AU - Familiar A AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Farahani, Keyvan AU - Farahani K AD - Cancer Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. FAU - Haldar, Shuvanjan AU - Haldar S AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Biomedical Engineering Rutgers University, New Brunswick, NJ, USA. FAU - Iglesias, Juan Eugenio AU - Iglesias JE AD - Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA. FAU - Janas, Anastasia AU - Janas A AD - Yale University, New Haven, CT, USA. FAU - Johansen, Elaine AU - Johansen E AD - PrecisionFDA, U.S. Food and Drug Administration, Silver Spring, MD, USA. FAU - Jones, Blaise V AU - Jones BV AUID- ORCID: 0000-0001-9003-4578 AD - Cincinnati Children's Hospital Medical Center. FAU - Kofler, Florian AU - Kofler F AD - Helmholtz AI, Helmholtz Munich, Germany. FAU - LaBella, Dominic AU - LaBella D AD - Department of Radiation Oncology, Duke University Medical Center, USA. FAU - Lai, Hollie Anne AU - Lai HA AUID- ORCID: 0000-0001-6747-7338 AD - Department of Radiology, Children's Health Orange County, CA, USA. FAU - Van Leemput, Koen AU - Van Leemput K AD - Department of Applied Mathematics and Computer Science, Technical University of Denmark, Denmark. FAU - Li, Hongwei Bran AU - Li HB AD - Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, USA. FAU - Maleki, Nazanin AU - Maleki N AD - Yale University, New Haven, CT, USA. FAU - McAllister, Aaron S AU - McAllister AS AUID- ORCID: 0000-0002-1117-9355 AD - Department of Radiology, Nationwide Children's Hospital, OH. FAU - Meier, Zeke AU - Meier Z AD - Booz Allen Hamilton, McLean, VA, USA. FAU - Menze, Bjoern AU - Menze B AD - Biomedical Image Analysis & Machine Learning, Department of Quantitative Biomedicine, University of Zurich, Switzerland. AD - Department of Neuroradiology, Technical University of Munich, Munich, Germany. FAU - Moawad, Ahmed W AU - Moawad AW AD - Mercy Catholic Medical Center, Darby, PA, USA. FAU - Nandolia, Khanak K AU - Nandolia KK AUID- ORCID: 0000-0002-8627-2992 AD - Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Rishikesh, India. FAU - Pavaine, Julija AU - Pavaine J AUID- ORCID: 0000-0003-1843-837X AD - Department of Paediatric Radiology, Royal Manchester Children's Hospital, Manchester University Hospitals NHS Foundation Trust, University of Manchester, Manchester, UK. AD - Division of Informatics, Imaging & Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK. FAU - Piraud, Marie AU - Piraud M AD - Helmholtz AI, Helmholtz Munich, Germany. FAU - Poussaint, Tina AU - Poussaint T AD - Dana-Farber Brigham Cancer Center & Boston Children's Hospital, Boston, MA, USA. FAU - Prabhu, Sanjay P AU - Prabhu SP AUID- ORCID: 0000-0003-0871-115X AD - Division of Neuroradiology, Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA. FAU - Reitman, Zachary AU - Reitman Z AD - Department of Radiation Oncology, Duke University Medical Center, USA. FAU - Rodriguez, Andres AU - Rodriguez A AUID- ORCID: 0000-0002-5366-5351 AD - Department of Diagnostic & Interventional Imaging, Neuroradiology section. The University of Texas Health Sciences Center at Houston. FAU - Rudie, Jeffrey D AU - Rudie JD AUID- ORCID: 0000-0000-0000-0000 AD - University of California, San Diego, CA, USA. FAU - Sanchez-Montano, Mariana AU - Sanchez-Montano M AUID- ORCID: 0000-0002-9203-1060 AD - UNIDAD DE PATOLOGIA CLINICA: Guadalajara, JALISCO, Mexico. FAU - Shaikh, Ibraheem Salman AU - Shaikh IS AUID- ORCID: 0000-0002-5994-997 AD - Beth Israel Deaconess Medical Center, Harvard Medical School, MA, USA. FAU - Shah, Lubdha M AU - Shah LM AUID- ORCID: 0000-0003-1303-3533 AD - University of Utah, UT, USA. FAU - Sheth, Nakul AU - Sheth N AD - Department of Radiology, The Children's Hospital of Philadelphia, PA, USA. FAU - Shinohara, Russel Taki AU - Shinohara RT AD - Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, USA. FAU - Tu, Wenxin AU - Tu W AUID- ORCID: 0000-0003-3649-2994 AD - College of Arts and Sciences, University of Pennsylvania, PA, USA. FAU - Viswanathan, Karthik AU - Viswanathan K AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. FAU - Wang, Chunhao AU - Wang C AD - Department of Radiation Oncology, Duke University Medical Center, USA. FAU - Ware, Jeffrey B AU - Ware JB AD - Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. FAU - Wiestler, Benedikt AU - Wiestler B AD - Department of Neuroradiology, Technical University of Munich, Munich, Germany. FAU - Wiggins, Walter AU - Wiggins W AD - Department of Radiology, Duke University Medical Center, USA. FAU - Zapaishchykova, Anna AU - Zapaishchykova A AD - Dana-Farber Brigham Cancer Center & Boston Children's Hospital, Boston, MA, USA. FAU - Aboian, Mariam AU - Aboian M AUID- ORCID: 0000-0002-4877-8271 AD - Yale University, New Haven, CT, USA. FAU - Bornhorst, Miriam AU - Bornhorst M AUID- ORCID: 0000-0000-0000-0000 AD - Brain Tumor Institute, Children's National Hospital, Washington, DC, USA. FAU - de Blank, Peter AU - de Blank P AD - Brain Tumor Center, Cincinnati Children's Hospital, Cincinnati, OH, USA. FAU - Deutsch, Michelle AU - Deutsch M AD - Pediatric Neuro-Oncology Program, Nationwide Children's Hospital, Columbus, OH, US. FAU - Fouladi, Maryam AU - Fouladi M AD - Pediatric Neuro-Oncology Program, Nationwide Children's Hospital, Columbus, OH, US. FAU - Hoffman, Lindsey AU - Hoffman L AD - Center for Cancer and Blood Disorders, Phoenix Children's Hospital, Phoenix, AZ, US. FAU - Kann, Benjamin AU - Kann B AD - Dana-Farber Brigham Cancer Center & Boston Children's Hospital, Boston, MA, USA. FAU - Lazow, Margot AU - Lazow M AD - Pediatric Neuro-Oncology Program, Nationwide Children's Hospital, Columbus, OH, US. FAU - Mikael, Leonie AU - Mikael L AD - Pediatric Neuro-Oncology Program, Nationwide Children's Hospital, Columbus, OH, US. FAU - Nabavizadeh, Ali AU - Nabavizadeh A AUID- ORCID: 0000-0002-0380-4552 AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. FAU - Packer, Roger AU - Packer R AD - Brain Tumor Institute, Children's National Hospital, Washington, DC, USA. FAU - Resnick, Adam AU - Resnick A AUID- ORCID: 0000-0003-0436-4189 AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA. FAU - Rood, Brian AU - Rood B AD - Center for Cancer and Blood Disorders, Children's National Hospital, Washington, DC, USA. FAU - Vossough, Arastoo AU - Vossough A AUID- ORCID: 0000-0003-1346-427X AD - Center for Data-Driven Discovery in Biomedicine (D3b), Children's Hospital of Philadelphia, Philadelphia, PA, USA. AD - Mercy Catholic Medical Center, Darby, PA, USA. FAU - Bakas, Spyridon AU - Bakas S AUID- ORCID: 0000-0001-8734-6482 AD - Center for AI & Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA), University of Pennsylvania, Philadelphia, PA, USA. AD - Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. AD - Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. FAU - Linguraru, Marius George AU - Linguraru MG AUID- ORCID: 0000-0001-6175-8665 AD - Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Hospital, Washington DC, USA. AD - Departments of Radiology and Pediatrics, George Washington University School of Medicine and Health Sciences, Washington, DC, USA. LA - eng GR - U01 CA242871/CA/NCI NIH HHS/United States GR - UH3 CA236536/CA/NCI NIH HHS/United States PT - Preprint DEP - 20240308 PL - United States TA - ArXiv JT - ArXiv JID - 101759493 PMC - PMC10246083 OTO - NOTNLM OT - AI OT - BraTS OT - BraTS-PEDs OT - artificial intelligence OT - brain OT - challenge OT - deep learning OT - machine learning OT - pediatric OT - segmentation OT - tumor OT - volume EDAT- 2023/06/09 06:42 MHDA- 2023/06/09 06:43 PMCR- 2024/03/08 CRDT- 2023/06/09 04:23 PHST- 2023/06/09 06:42 [pubmed] PHST- 2023/06/09 06:43 [medline] PHST- 2023/06/09 04:23 [entrez] PHST- 2024/03/08 00:00 [pmc-release] AID - 2305.17033 [pii] PST - epublish SO - ArXiv [Preprint]. 2024 Mar 8:arXiv:2305.17033v6.