PMID- 37293192 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230612 IS - 1179-1462 (Electronic) IS - 1179-1462 (Linking) VI - 15 DP - 2023 TI - A Unique Way of Treatment of Giant Cell Tumor of the Distal Femur in a 19-Year-Old Female, a Case Report. PG - 119-127 LID - 10.2147/ORR.S402927 [doi] AB - Giant Cell tumors (GCT) are benign tumors with aggressive characteristics and the potential to metastasize. These are seldom lethal benign bone tumors but are associated with massive local bony architecture distraction making their treatment difficult, especially if found in peri-articular locations. Several long bone giant cell tumor (GCT) cases have been reported. We report a unique treatment of distal femur GCT in a 19-year-old in a resource-limited setup whose initial presentation was following a pathologic fracture. We used a staged surgical protocol. In the first stage, distal femur resection and implantation of poly methyl methacrylate (PMMA) cement spacer for induced membrane formation was done, followed by SIGN nail and non-vascularized fibula strut graft. There was adequate healing and no recurrence was noted during the two-year follow-up. CI - (c) 2023 Alemayehu and Kebede. FAU - Alemayehu, Elsa Daniel AU - Alemayehu ED AUID- ORCID: 0000-0003-1784-2936 AD - Department of Orthopedic Surgery and Trauma, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia. FAU - Kebede, Eskinder AU - Kebede E AD - Department of Orthopedic Surgery and Trauma, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia. LA - eng PT - Case Reports DEP - 20230603 PL - New Zealand TA - Orthop Res Rev JT - Orthopedic research and reviews JID - 101531415 PMC - PMC10246779 OTO - NOTNLM OT - GCT OT - PMMA OT - SIGN nail OT - distal femur OT - fracture OT - giant cell tumor OT - peri-articular OT - polymethyl methacrylate OT - vascularized fibula graft COIS- We certify that there is no conflict of interest with any financial organization regarding the material discussed in the case report. EDAT- 2023/06/09 06:42 MHDA- 2023/06/09 06:43 PMCR- 2023/06/03 CRDT- 2023/06/09 04:31 PHST- 2023/03/22 00:00 [received] PHST- 2023/06/01 00:00 [accepted] PHST- 2023/06/09 06:43 [medline] PHST- 2023/06/09 06:42 [pubmed] PHST- 2023/06/09 04:31 [entrez] PHST- 2023/06/03 00:00 [pmc-release] AID - 402927 [pii] AID - 10.2147/ORR.S402927 [doi] PST - epublish SO - Orthop Res Rev. 2023 Jun 3;15:119-127. doi: 10.2147/ORR.S402927. eCollection 2023.