PMID- 37296765
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230612
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 13
IP  - 11
DP  - 2023 May 30
TI  - Fat Hounsfield Unit Reference Interval Derived through an Indirect Method.
LID - 10.3390/diagnostics13111913 [doi]
LID - 1913
AB  - BACKGROUND: In vivo Hounsfield Unit (HU) values have traditionally been 
      determined using direct CT image measurements. These measurements are dependent 
      on the window/level used to examine the CT image and the individual conducting 
      the fat tissue tracing. METHODS: Using an indirect method, a new reference 
      interval (RI) is proposed. A total of 4000 samples of fat tissues were collected 
      from routine abdominal CT examinations. A linear regression equation was then 
      calculated using the linear part of the cumulative frequency plot of their 
      average values. RESULTS: The regression function for total abdominal fat was 
      determined to be y = 35.376*x - 123.48, and a 95% confidence RI of -123 to -89 
      was computed. A significant difference of 3.82 was observed between the average 
      fat HU values of visceral and subcutaneous areas. CONCLUSIONS: Using statistical 
      methods and the in vivo measurements of patient data, a series of RIs were 
      determined for fat HU that is consistent with theoretical values.
FAU - Pop, Marian
AU  - Pop M
AUID- ORCID: 0000-0001-5324-9780
AD  - ME1 Department, George Emil Palade University of Medicine, Pharmacy, Science, and 
      Technology of Targu Mures, 540139 Tirgu Mures, Romania.
AD  - Radiology and Medical Imaging Department, Tirgu Mures Emergency Institute for 
      Cardiovascular Diseases and Heart Transplant, 540136 Tirgu Mures, Romania.
FAU - Marusteri, Marius
AU  - Marusteri M
AD  - M2 Department, George Emil Palade University of Medicine, Pharmacy, Science, and 
      Technology of Targu Mures, 540139 Tirgu Mures, Romania.
LA  - eng
PT  - Journal Article
DEP - 20230530
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC10252728
OTO - NOTNLM
OT  - computed tomography
OT  - fat Hounsfield unit
OT  - indirect method
OT  - reference interval
COIS- The authors declare no conflict of interest.
EDAT- 2023/06/10 15:13
MHDA- 2023/06/10 15:14
PMCR- 2023/05/30
CRDT- 2023/06/10 01:02
PHST- 2023/04/23 00:00 [received]
PHST- 2023/05/23 00:00 [revised]
PHST- 2023/05/29 00:00 [accepted]
PHST- 2023/06/10 15:14 [medline]
PHST- 2023/06/10 15:13 [pubmed]
PHST- 2023/06/10 01:02 [entrez]
PHST- 2023/05/30 00:00 [pmc-release]
AID - diagnostics13111913 [pii]
AID - diagnostics-13-01913 [pii]
AID - 10.3390/diagnostics13111913 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2023 May 30;13(11):1913. doi: 10.3390/diagnostics13111913.