PMID- 37302642
OWN - NLM
STAT- MEDLINE
DCOM- 20230727
LR  - 20230727
IS  - 1873-507X (Electronic)
IS  - 0031-9384 (Linking)
VI  - 269
DP  - 2023 Oct 1
TI  - Psychological and medical treatments for binge-eating disorder: A research 
      update.
PG  - 114267
LID - S0031-9384(23)00192-0 [pii]
LID - 10.1016/j.physbeh.2023.114267 [doi]
AB  - Binge-eating disorder (BED), characterized by recurrent binge eating in the 
      absence of regular weight-compensatory behaviors, is the most common eating 
      disorder, associated with pronounced mental and physical sequelae. An increasing 
      body of research documents the efficacy of diverse approaches to the treatment of 
      this disorder, summarized in meta-analyses. This research update narratively 
      reviewed randomized-controlled trials (RCTs) on the psychological and medical 
      treatment of BED published between January 2018 and November 2022, identified 
      through a systematic literature search. A total of 16 new RCTs and 3 studies on 
      previous RCTs providing efficacy- and safety-related data were included. 
      Regarding psychotherapy, confirmatory evidence supported the use of 
      integrative-cognitive therapy and, with lower effects, brief emotion regulation 
      skills training for binge eating and associated psychopathology. Behavioral 
      weight loss treatment was revealed to be efficacious for binge eating, weight 
      loss, and psychopathology, but its combination with naltrexone-bupropion did not 
      augment efficacy. New treatment approaches were explored, including 
      e-mental-health and brain-directed treatments, mostly targeting emotion and 
      self-regulation. Additionally, different therapeutic approaches were evaluated in 
      complex stepped-care models. In light of these advances, future research is 
      necessary to further optimize effects of evidence-based treatments for BED, 
      through improvement of existing or development of new treatments, based on 
      mechanistic and/or interventional research, and/or tailoring treatments to 
      personal characteristics in a precision medicine approach.
CI  - Copyright (c) 2023. Published by Elsevier Inc.
FAU - Hilbert, Anja
AU  - Hilbert A
AD  - Integrated Research and Treatment Center AdiposityDiseases, Behavioral Medicine 
      Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University 
      of Leipzig Medical Center, Leipzig, Germany. Electronic address: 
      Anja.Hilbert@medizin.uni-leipzig.de.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230609
PL  - United States
TA  - Physiol Behav
JT  - Physiology & behavior
JID - 0151504
SB  - IM
MH  - Humans
MH  - *Binge-Eating Disorder/therapy/psychology
MH  - *Bulimia
MH  - *Cognitive Behavioral Therapy
MH  - Psychotherapy
MH  - Treatment Outcome
MH  - Weight Loss
MH  - Randomized Controlled Trials as Topic
OTO - NOTNLM
OT  - Binge-eating disorder
OT  - Pharmacotherapy
OT  - Psychotherapy
OT  - Self-help
OT  - Systematic review
OT  - Treatment
OT  - Weight loss treatment
COIS- Declaration of Competing Interest Professor Hilbert received: research grants on 
      eating disorders and obesity from the German Federal Ministry of Education and 
      Research, German Research Foundation, and Roland Ernst Foundation for Healthcare; 
      royalties for books on the treatment of eating disorders and obesity with 
      Hogrefe; honoraria for workshops and lectures on eating disorders and obesity and 
      their treatment; honoraria as editor of the International Journal of Eating 
      Disorders and the journal Psychotherapeut; honoraria as a reviewer from Mercator 
      Research Center Ruhr, Oxford University Press, and the German Society for 
      Nutrition; and honoraria as a consultant for WeightWatchers and Zweites Deutsches 
      Fernsehen.
EDAT- 2023/06/12 00:42
MHDA- 2023/07/24 06:42
CRDT- 2023/06/11 19:16
PHST- 2022/12/14 00:00 [received]
PHST- 2023/02/23 00:00 [revised]
PHST- 2023/06/08 00:00 [accepted]
PHST- 2023/07/24 06:42 [medline]
PHST- 2023/06/12 00:42 [pubmed]
PHST- 2023/06/11 19:16 [entrez]
AID - S0031-9384(23)00192-0 [pii]
AID - 10.1016/j.physbeh.2023.114267 [doi]
PST - ppublish
SO  - Physiol Behav. 2023 Oct 1;269:114267. doi: 10.1016/j.physbeh.2023.114267. Epub 
      2023 Jun 9.