PMID- 37306486
OWN - NLM
STAT- MEDLINE
DCOM- 20230614
LR  - 20230623
IS  - 1365-2060 (Electronic)
IS  - 0785-3890 (Print)
IS  - 0785-3890 (Linking)
VI  - 55
IP  - 1
DP  - 2023 Dec
TI  - Nomogram for predicting gallbladder stone in patients with type 2 diabetes 
      mellitus: a retrospective study in the Chinese population.
PG  - 2221899
LID - 10.1080/07853890.2023.2221899 [doi]
LID - 2221899
AB  - OBJECTIVE: The purpose of this study is to explore the risk factors of 
      gallbladder stone (GBS) in patients with type 2 diabetes mellitus (T2DM) and also 
      develop a simple-to-use nomogram for GBS in patients with T2DM. METHODS: This 
      study retrospectively analyzed 2243 patients with T2DM hospitalized in Peking 
      University International Hospital from January 2017 to August 2022. According to 
      the results of colour Doppler ultrasonic examinations, the patients were divided 
      into two groups. RESULTS: (1) Compared with the non-GBS group, the GBS group was 
      older (p < 0.05), and the diabetes duration in the GBS group was longer 
      (p < 0.05). The proportion of overweight and obese people in the GBS group was 
      significantly higher than that in the non-GBS group (p < 0.05, respectively). The 
      proportion of patients with diabetic nephropathy (DN) and diabetic peripheral 
      neuropathy (DPN) was higher in the GBS group (p < 0.05, respectively). (2) 
      Logistic regression showed that age, body mass index (BMI), diabetes duration, 
      total cholesterol (TC), triglycerides (TG), alanine aminotransferase (ALT), DN, 
      and DPN were independent risk factors for GBS (p < 0.05, respectively). (3) The 
      area under the curve (AUC) of the nomogram for GBS was 0.704 (95% CI 0.656, 
      0.748), with a specificity of 90.34%, a sensitivity of 55.38%, and an accuracy of 
      86.83%. CONCLUSION: The nomogram is accurate to a certain degree and provides a 
      clinical basis for predicting the incidence of GBS in patients with T2DM, which 
      has a certain predictive value.
FAU - Wu, Tiantian
AU  - Wu T
AD  - Department of Hepatobiliary Surgery, Peking University International Hospital, 
      Beijing, P.R. China.
FAU - Wang, Qiang
AU  - Wang Q
AD  - Department of Hepatobiliary Surgery, Peking University International Hospital, 
      Beijing, P.R. China.
FAU - Pu, Changsheng
AU  - Pu C
AD  - Department of Hepatobiliary Surgery, Peking University International Hospital, 
      Beijing, P.R. China.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Ann Med
JT  - Annals of medicine
JID - 8906388
SB  - IM
MH  - Humans
MH  - Retrospective Studies
MH  - *Diabetes Mellitus, Type 2
MH  - East Asian People
MH  - Gallbladder
MH  - Nomograms
MH  - *Diabetic Nephropathies
PMC - PMC10262805
OTO - NOTNLM
OT  - Gallbladder stone
OT  - HbA1c
OT  - nomogram
OT  - type 2 diabetes mellitus
COIS- No potential conflict of interest was reported by the author(s).
EDAT- 2023/06/12 13:07
MHDA- 2023/06/14 06:42
PMCR- 2023/06/12
CRDT- 2023/06/12 09:22
PHST- 2023/06/14 06:42 [medline]
PHST- 2023/06/12 13:07 [pubmed]
PHST- 2023/06/12 09:22 [entrez]
PHST- 2023/06/12 00:00 [pmc-release]
AID - 2221899 [pii]
AID - 10.1080/07853890.2023.2221899 [doi]
PST - ppublish
SO  - Ann Med. 2023 Dec;55(1):2221899. doi: 10.1080/07853890.2023.2221899.