PMID- 37310004 OWN - NLM STAT- MEDLINE DCOM- 20240306 LR - 20240306 IS - 1876-3405 (Electronic) IS - 1876-3413 (Print) IS - 1876-3405 (Linking) VI - 16 IP - 2 DP - 2024 Mar 4 TI - Low medication adherence and its associated factors among patients with type 2 diabetes mellitus attending Amana Hospital in Dar es Salaam, Tanzania: a cross-sectional study. PG - 200-207 LID - 10.1093/inthealth/ihad042 [doi] AB - BACKGROUND: Low medication adherence among patients with type 2 diabetes mellitus (T2DM) is associated with significant morbidity and mortality globally. We investigated the prevalence of low medication adherence and its associated factors among patients with T2DM. METHODS: We used the Bengali version of the 8-item Morisky Medication Adherence Scale (MMAS-8) in measuring medication adherence among patients with T2DM who were attending the diabetes clinic at Amana Regional Referral Hospital in Dar es Salaam, Tanzania, from December 2021 to May 2022. Binary logistic regression analysis under multivariate analysis was used to determine the predictors of low medication adherence after controlling for confounders. A two-tailed p-value <0.05 was considered significant. RESULTS: The prevalence of low medication adherence was 36.7% (91/248) of the subjects included in the study. Lack of formal education (adjusted odds ratio [AOR] 5.3 [95% confidence interval CI 1.717 to 16.312], p=0.004), having comorbidities (AOR 2.1 [95% CI 1.134 to 3.949], p=0.019) and drinking alcohol (AOR 3.5 [95% CI 1.603 to 7.650], p=0.031) were the independent predictors of low medication adherence. CONCLUSION: More than one-third of the patients with T2DM in this study had low medication adherence. Our study also showed that a lack of formal education, having comorbidities and drinking alcohol were significantly associated with low medication adherence. CI - (c) The Author(s) 2023. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. FAU - Doya, Irene F AU - Doya IF AD - Department of Community Medicine, School of Medicine and Dentistry, University of Dodoma, Dodoma, Tanzania. FAU - Yahaya, James J AU - Yahaya JJ AD - Department of Pathology, School of Health Sciences, Soroti University, P. O. Box 211, Soroti, Uganda. FAU - Ngaiza, Advera I AU - Ngaiza AI AD - Department of Pathology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. AD - Department of Pathology, Muhimbili National Hospital, Dar es Salaam, Tanzania. FAU - Bintabara, Deogratius AU - Bintabara D AD - Department of Community Medicine, School of Medicine and Dentistry, University of Dodoma, Dodoma, Tanzania. LA - eng PT - Journal Article PL - England TA - Int Health JT - International health JID - 101517095 SB - IM MH - Humans MH - *Diabetes Mellitus, Type 2/drug therapy MH - Cross-Sectional Studies MH - Tanzania/epidemiology MH - Medication Adherence MH - Hospitals PMC - PMC10911532 OTO - NOTNLM OT - low medication adherence OT - risk factors OT - type 2 diabetes mellitus COIS- None declared. EDAT- 2023/06/13 13:12 MHDA- 2024/03/06 06:44 PMCR- 2023/06/13 CRDT- 2023/06/13 07:53 PHST- 2023/01/26 00:00 [received] PHST- 2023/04/22 00:00 [revised] PHST- 2023/05/19 00:00 [accepted] PHST- 2024/03/06 06:44 [medline] PHST- 2023/06/13 13:12 [pubmed] PHST- 2023/06/13 07:53 [entrez] PHST- 2023/06/13 00:00 [pmc-release] AID - 7195075 [pii] AID - ihad042 [pii] AID - 10.1093/inthealth/ihad042 [doi] PST - ppublish SO - Int Health. 2024 Mar 4;16(2):200-207. doi: 10.1093/inthealth/ihad042.