PMID- 37319165 OWN - NLM STAT- MEDLINE DCOM- 20230619 LR - 20231120 IS - 1932-6203 (Electronic) IS - 1932-6203 (Linking) VI - 18 IP - 6 DP - 2023 TI - Assessing the critical success factors for implementing industry 4.0 in the pharmaceutical industry: Implications for supply chain sustainability in emerging economies. PG - e0287149 LID - 10.1371/journal.pone.0287149 [doi] LID - e0287149 AB - The emerging technologies of Industry 4.0 (I4.0) are crucial to incorporating agility, sustainability, smartness, and competitiveness in the business model, enabling long-term sustainability practices in the pharmaceutical supply chain (PSC). By leveraging the latest technologies of I4.0, pharmaceutical companies can gain real-time visibility into their supply chain (SC) operations, allowing them to make data-driven decisions that improve SC performance, efficiency, resilience, and sustainability. However, to date, no research has examined the critical success factors (CSFs) that enable the pharmaceutical industry to adopt I4.0 successfully to enhance overall SC sustainability. This study, therefore, analyzed the potential CSFs for adopting I4.0 to increase all facets of sustainability in the PSC, especially from the perspective of an emerging economy like Bangladesh. Initially, sixteen CSFs were identified through a comprehensive literature review and expert validation. Later, the finalized CSFs were clustered into three relevant groups and analyzed using a Bayesian best-worst method (BWM)-based multi-criteria decision-making (MCDM) framework. The study findings revealed that "sufficient investment for technological advancement", "digitalized product monitoring and traceability", and "dedicated and robust research and development (R&D) team" are the top three CSFs to adopt I4.0 in the PSC. The study's findings can aid industrial practitioners, managers, and policymakers in creating effective action plans for efficiently adopting I4.0 in PSC to avail of its competitive benefits and ensure a sustainable future for the pharmaceutical industry. CI - Copyright: (c) 2023 Debnath et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. FAU - Debnath, Binoy AU - Debnath B AUID- ORCID: 0000-0001-9047-1428 AD - Department of Industrial and Production Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh. FAU - Shakur, Md Shihab AU - Shakur MS AUID- ORCID: 0000-0001-8873-5877 AD - Department of Industrial and Production Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh. FAU - Bari, A B M Mainul AU - Bari ABMM AUID- ORCID: 0000-0002-3075-4247 AD - Department of Industrial and Production Engineering, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh. FAU - Saha, Joy AU - Saha J AD - Department of Mechanical and Production Engineering, Ahsanullah University of Science and Technology, Dhaka, Bangladesh. FAU - Porna, Wazida Akter AU - Porna WA AUID- ORCID: 0009-0006-3251-9730 AD - Department of Mechanical and Production Engineering, Ahsanullah University of Science and Technology, Dhaka, Bangladesh. FAU - Mishu, Mostarin Jahan AU - Mishu MJ AD - Department of Mechanical and Production Engineering, Ahsanullah University of Science and Technology, Dhaka, Bangladesh. FAU - Islam, Abu Reza Md Towfiqul AU - Islam ARMT AUID- ORCID: 0000-0001-5779-1382 AD - Department of Disaster Management, Begum Rokeya University, Rangpur, Bangladesh. FAU - Rahman, Muhommad Azizur AU - Rahman MA AUID- ORCID: 0000-0002-4299-3085 AD - Department of Mechanical and Production Engineering, Ahsanullah University of Science and Technology, Dhaka, Bangladesh. LA - eng PT - Journal Article PT - Review DEP - 20230615 PL - United States TA - PLoS One JT - PloS one JID - 101285081 RN - 0 (Pharmaceutical Preparations) SB - IM MH - Bayes Theorem MH - *Commerce MH - *Drug Industry MH - Investments MH - Pharmaceutical Preparations PMC - PMC10270361 COIS- The authors have declared that no competing interests exist. EDAT- 2023/06/15 19:14 MHDA- 2023/06/19 13:08 PMCR- 2023/06/15 CRDT- 2023/06/15 13:54 PHST- 2023/05/07 00:00 [received] PHST- 2023/06/01 00:00 [accepted] PHST- 2023/06/19 13:08 [medline] PHST- 2023/06/15 19:14 [pubmed] PHST- 2023/06/15 13:54 [entrez] PHST- 2023/06/15 00:00 [pmc-release] AID - PONE-D-23-13927 [pii] AID - 10.1371/journal.pone.0287149 [doi] PST - epublish SO - PLoS One. 2023 Jun 15;18(6):e0287149. doi: 10.1371/journal.pone.0287149. eCollection 2023.