PMID- 37324573
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230918
IS  - 2377-9608 (Electronic)
IS  - 2377-9608 (Linking)
VI  - 9
DP  - 2023 Jan-Dec
TI  - Intervention for Prevention of Type 2 Diabetes Mellitus Among Prediabetes: A 
      Review of the Literature.
PG  - 23779608231175581
LID - 10.1177/23779608231175581 [doi]
LID - 23779608231175581
AB  - INTRODUCTION: In recent decades, the prevalence and incidence of type 2 diabetes 
      mellitus (T2DM) have increased rapidly and represent a significant public health 
      problem worldwide. Long-term T2DM is associated with microvascular complications 
      such as retinopathy, nephropathy, and neuropathy. Prediabetes is a state of 
      hyperglycemia with blood glucose levels higher than normal but lower than the 
      diabetes threshold. Several studies have demonstrated the effectiveness of 
      lifestyle interventions that resulted in a 40% to 70% reduction in diabetes 
      mellitus in adults with prediabetes. These interventions focused on increased 
      physical activity and dietary changes that were able to prevent or delay the 
      onset of T2DM in prediabetes. However, most review studies focused on 
      interventions to prevent T2DM in high-risk groups such as obesity. There was a 
      limitation of reports related to prediabetes. Nevertheless, it remains a 
      high-risk condition for the development of T2DM with a conversion rate of 5% to 
      10% per year. Therefore, the aim of this study was to review the current evidence 
      on intervention studies aimed at reducing the incidence of type 2 diabetes in 
      prediabetes. METHOD: The researcher conducted a literature search of common 
      online databases such as Medline, Google Scholar, and Cochrane Library between 
      January 2011 and December 2021. RESULT: The intervention for the prevention of 
      T2DM in prediabetes consisted of a lifestyle intervention, a nutritional 
      supplementation intervention, and a pharmacological intervention. CONCLUSION: 
      Several studies suggest that T2DM in prediabetes can be prevented by lifestyle 
      modification and pharmacological interventions, or a combined intervention. 
      However, further interventions may be needed to confirm this.
CI  - (c) The Author(s) 2023.
FAU - Thipsawat, Sopida
AU  - Thipsawat S
AUID- ORCID: 0000-0002-7666-7384
AD  - Excellence Center of Community Health Promotion, School of Nursing, Walailak 
      University, Nakhon Si Thammarat, Thailand. RINGGOLD: 65133
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230604
PL  - United States
TA  - SAGE Open Nurs
JT  - SAGE open nursing
JID - 101724853
PMC - PMC10265340
OTO - NOTNLM
OT  - impaired fasting glucose
OT  - impaired glucose tolerance
OT  - incidence
OT  - prediabetes
OT  - prevention
OT  - type 2 diabetes mellitus
COIS- The author declared no potential conflicts of interest with respect to the 
      research, authorship and/or publication of this article.
EDAT- 2023/06/16 06:42
MHDA- 2023/06/16 06:43
PMCR- 2023/06/04
CRDT- 2023/06/16 04:13
PHST- 2022/10/05 00:00 [received]
PHST- 2023/03/16 00:00 [revised]
PHST- 2023/04/23 00:00 [accepted]
PHST- 2023/06/16 06:42 [pubmed]
PHST- 2023/06/16 06:43 [medline]
PHST- 2023/06/16 04:13 [entrez]
PHST- 2023/06/04 00:00 [pmc-release]
AID - 10.1177_23779608231175581 [pii]
AID - 10.1177/23779608231175581 [doi]
PST - epublish
SO  - SAGE Open Nurs. 2023 Jun 4;9:23779608231175581. doi: 10.1177/23779608231175581. 
      eCollection 2023 Jan-Dec.