PMID- 37324837
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230619
IS  - 2048-7177 (Print)
IS  - 2048-7177 (Electronic)
IS  - 2048-7177 (Linking)
VI  - 11
IP  - 6
DP  - 2023 Jun
TI  - The effects of purslane consumption on glycemic control and oxidative stress: A 
      systematic review and dose-response meta-analysis.
PG  - 2530-2546
LID - 10.1002/fsn3.3311 [doi]
AB  - Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of 
      pharmaceutic properties. Although the beneficial effect of purslane on the 
      treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an 
      inconsistency among the results of previous studies. Therefore, this study is 
      aimed at conducting a systematic review and meta-analysis on the effect of 
      purslane on glycemic profile and oxidative stress markers. A systematic search 
      was performed in the Scopus, Web of science, PubMed and the Cochrane Library to 
      find articles related to the effect of the purslane on Malondialdehyde (MDA) and 
      Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c 
      (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance 
      (HOMA-IR) up to September 2022. Among the 611 initial studies that were 
      identified from searching electronic databases, 16 Randomized Clinical Trials 
      (RCTs) involving 1122 participants (557 cases and 565 controls) were included for 
      data analysis. The results of random-effects modeling demonstrated that purslane 
      consumption significantly reduced FBS (p < .001), MDA (p < .001) and increased 
      TAC (p < .001). However, purslane consumption did not affect HbA1c (p < .109), 
      fasting insulin (p = .298) and HOMA-IR (p = .382). Meta-analyses were performed 
      using both the random- and fixed-effects model where appropriate, and I (2) index 
      was used to evaluate the heterogeneity. This meta-analysis study suggests that 
      purslane has beneficial effects on oxidative stress markers and glycemic 
      parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of 
      its benefits and negligible adverse effects.
CI  - (c) 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC.
FAU - Jafari, Naser
AU  - Jafari N
AD  - University of Applied Science and Technology - Allameh Tabarsi Center Tehran 
      Iran.
FAU - Shoaibinobarian, Nargeskhatoon
AU  - Shoaibinobarian N
AD  - Department of Nutrition, School of Medical Sciences and Technologies Islamic Azad 
      University, Science and Research Branch Tehran Iran.
FAU - Dehghani, Azadeh
AU  - Dehghani A
AD  - Nutrition Research Center, Department of Community Nutrition, Faculty of 
      Nutrition and Food Science Tabriz University of Medical Sciences Tabriz Iran.
FAU - Rad, Amirhosein
AU  - Rad A
AD  - Nutrition Department, Faculty of Health and Nutrition Lorestan University of 
      Medical Sciences Khoramabad Iran.
FAU - Mirmohammadali, Seyedeh Nooshan
AU  - Mirmohammadali SN
AD  - Department of Food, Nutrition, Dietetics and Health Kansas State University 
      Manhattan Kansas USA.
FAU - Alaeian, Mohammad Javad
AU  - Alaeian MJ
AD  - MD graduated from Shahid Beheshti University of Medical sciences Tehran Iran.
FAU - Hamedi, Yasaman
AU  - Hamedi Y
AD  - Department of Physical Education Central Tehran Branch, Islamic Azad University 
      Tehran Iran.
FAU - Zamani, Mohamad
AU  - Zamani M
AD  - Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics 
      Tehran University of Medical Sciences Tehran Iran.
FAU - Goudarzi, Mohammad Ali
AU  - Goudarzi MA
AD  - Shahrekord Branch Islamic Azad University Shahrekord Iran.
FAU - Asbaghi, Omid
AU  - Asbaghi O
AUID- ORCID: 0000-0002-7740-4711
AD  - Cancer Research Center Shahid Beheshti University of Medical sciences Tehran 
      Iran.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230315
PL  - United States
TA  - Food Sci Nutr
JT  - Food science & nutrition
JID - 101605473
PMC - PMC10261734
OTO - NOTNLM
OT  - glycemic
OT  - meta-analysis
OT  - oxidative stress
OT  - purslane
OT  - systematic review
COIS- The authors declared that there is no conflict of interest.
EDAT- 2023/06/16 06:42
MHDA- 2023/06/16 06:43
PMCR- 2023/03/15
CRDT- 2023/06/16 04:16
PHST- 2022/10/07 00:00 [received]
PHST- 2023/01/17 00:00 [revised]
PHST- 2023/02/24 00:00 [accepted]
PHST- 2023/06/16 06:43 [medline]
PHST- 2023/06/16 06:42 [pubmed]
PHST- 2023/06/16 04:16 [entrez]
PHST- 2023/03/15 00:00 [pmc-release]
AID - FSN33311 [pii]
AID - 10.1002/fsn3.3311 [doi]
PST - epublish
SO  - Food Sci Nutr. 2023 Mar 15;11(6):2530-2546. doi: 10.1002/fsn3.3311. eCollection 
      2023 Jun.