PMID- 37328645
OWN - NLM
STAT- MEDLINE
DCOM- 20230727
LR  - 20231119
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 33
IP  - 8
DP  - 2023 Aug
TI  - Predictors of T2DM Remission after Bariatric Surgery in Patients with a 
      BMI < 35 kg/m(2): a Meta-Analysis.
PG  - 2342-2355
LID - 10.1007/s11695-023-06671-7 [doi]
AB  - PURPOSE: Although a few studies have reported the predictors of postoperative 
      diabetes remission in patients with body mass index (BMI) < 35 kg/m(2), the 
      conclusions are still inconsistent. This meta-analysis aimed to evaluate the 
      preoperative clinical factors of type 2 diabetes mellitus (T2DM) remission after 
      bariatric surgery. MATERIALS AND METHODS: The PubMed, Embase, and Cochrane 
      Library databases were systematically searched until April 2022. The 
      Newcastle-Ottawa Scale was used for quality assessment. Statistical heterogeneity 
      was assessed with the I(2) statistic, followed by subgroup and sensitivity 
      analyses. RESULTS: 16 studies involving 932 patients were selected. T2DM 
      remission was negatively correlated with age, duration, insulin use, fasting 
      plasma glucose, fasting insulin, and glycosylated hemoglobin levels. While BMI, 
      body weight, waist circumference, and C-peptide levels were positive predictors 
      of T2DM remission in patients with a BMI < 35 kg/m(2). However, there was no 
      significant association between gender, oral hypoglycemic agent, homeostasis 
      model assessment, high-density lipoprotein, low-density lipoprotein, total 
      cholesterol, triglycerides, systolic blood pressure, diastolic blood pressure, 
      and remission rate. CONCLUSION: Patients with younger age, short diabetes 
      duration, more obesity, better glucose control, and better beta cell function were 
      more likely to achieve T2DM remission in patients with a BMI < 35 kg/m(2) after 
      bariatric surgery.
CI  - (c) 2023. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Yi, Xianhao
AU  - Yi X
AD  - Department of General Surgery, The Third Xiangya Hospital, Central South 
      University, Changsha, 410013, Hunan, China.
FAU - Zhu, Liyong
AU  - Zhu L
AD  - Department of General Surgery, The Third Xiangya Hospital, Central South 
      University, Changsha, 410013, Hunan, China. zly8128@csu.edu.cn.
FAU - Zhu, Shaihong
AU  - Zhu S
AUID- ORCID: 0000-0001-6209-3132
AD  - Department of General Surgery, The Third Xiangya Hospital, Central South 
      University, Changsha, 410013, Hunan, China. shaihongzhu@126.com.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
DEP - 20230616
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin)
RN  - 0 (Insulin)
SB  - IM
MH  - Humans
MH  - *Bariatric Surgery
MH  - Blood Glucose
MH  - Body Mass Index
MH  - *Diabetes Mellitus, Type 2/complications/surgery
MH  - Glycated Hemoglobin
MH  - Insulin
MH  - *Obesity, Morbid/surgery
MH  - Remission Induction
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Bariatric surgery
OT  - Body mass index < 35 kg/m2
OT  - Diabetes remission
OT  - Type 2 diabetes
EDAT- 2023/06/17 05:11
MHDA- 2023/07/17 06:42
CRDT- 2023/06/16 23:28
PHST- 2023/01/10 00:00 [received]
PHST- 2023/06/07 00:00 [accepted]
PHST- 2023/05/23 00:00 [revised]
PHST- 2023/07/17 06:42 [medline]
PHST- 2023/06/17 05:11 [pubmed]
PHST- 2023/06/16 23:28 [entrez]
AID - 10.1007/s11695-023-06671-7 [pii]
AID - 10.1007/s11695-023-06671-7 [doi]
PST - ppublish
SO  - Obes Surg. 2023 Aug;33(8):2342-2355. doi: 10.1007/s11695-023-06671-7. Epub 2023 
      Jun 16.