PMID- 37329652
OWN - NLM
STAT- MEDLINE
DCOM- 20230809
LR  - 20230809
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1705
DP  - 2023 Aug 30
TI  - Two-dimensional boron nanosheets for selective enrichment and detection of 
      cis-diol compounds by surface-assisted laser desorption/ionization time-of-flight 
      mass spectrometry.
PG  - 464142
LID - S0021-9673(23)00368-0 [pii]
LID - 10.1016/j.chroma.2023.464142 [doi]
AB  - Surface-assisted laser desorption/ionization time-of-flight mass spectrometry 
      (SALDI-TOF MS) is an effective method for detecting of low-mass molecules. In 
      this study, two-dimensional boron nanosheets (2DBs) were fabricated through 
      thermal oxidation etching and coupling liquid exfoliation technologies, and 
      applied as a matrix and selective sorbent for detecting cis-diol compounds by 
      SALDI-TOF MS. The outstanding nanostructure and boric acid active sites of 2DBs 
      endow them with sensitivity for cis-diol compound detection, excellent 
      selectivity, and low background interference for complex samples. The specific 
      in-situ enrichment faculty of the 2DBs as a matrix was investigated by SALDI-TOF 
      MS using glucose, arabinose, and lactose as model analytes. In the presence of 
      100 -fold more interfering substances, the 2DBs showed high selectivity against 
      cis-diol compounds, and exhibited a better sensitivity and a reduced limit of 
      detection through enrichment treatment than graphene oxide matrices. The 
      linearity, limit of detection (LOD), reproducibility, and accuracy of the method 
      were evaluated under optimized conditions. The results showed that the linear 
      relationships of six saccharides remained in the range of 0.05-0.6 mM with a 
      correlation coefficient r >/=0.98. The LODs of six saccharides were 1 nM (glucose, 
      lactose, mannose, fructose) and 10 nM (galactose, arabinose). Sample-to-sample 
      (n = 6) with relative standard deviations (RSDs) of 3.2% to 8.1% were observed. 
      Recoveries (n = 5) of 87.9-104.6% were obtained at three spiked levels in the 
      milk samples. The proposed strategy promoted the development of a matrix for use 
      with SALDI-TOF MS detection, in which the UV absorption properties and enrichment 
      capabilities of 2DBs were combined.
CI  - Copyright (c) 2023. Published by Elsevier B.V.
FAU - Wang, Xian
AU  - Wang X
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China; 
      School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
FAU - Qin, ShiJiang
AU  - Qin S
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China.
FAU - Zheng, Guocan
AU  - Zheng G
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China; 
      School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 
      401331, China. Electronic address: gczheng@cqu.edu.cn.
FAU - Wei, Weili
AU  - Wei W
AD  - School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
FAU - Li, Fang
AU  - Li F
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China.
FAU - Luo, Yao
AU  - Luo Y
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China.
FAU - Tang, JinJing
AU  - Tang J
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China; 
      School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 
      401331, China.
FAU - Zhou, Kai
AU  - Zhou K
AD  - Analytical and Testing Center, Chongqing University, Chongqing 401331, China.
LA  - eng
PT  - Journal Article
DEP - 20230611
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - N9E3X5056Q (Boron)
RN  - B40ROO395Z (Arabinose)
RN  - J2B2A4N98G (Lactose)
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
MH  - *Boron
MH  - *Arabinose
MH  - Lactose
MH  - Reproducibility of Results
MH  - Glucose
MH  - Lasers
OTO - NOTNLM
OT  - Cis-diol compounds
OT  - SALDI-TOF MS
OT  - Selective enrichment
OT  - Two-dimensional boron nanosheets
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/06/18 01:07
MHDA- 2023/08/09 06:43
CRDT- 2023/06/17 18:02
PHST- 2023/02/15 00:00 [received]
PHST- 2023/06/05 00:00 [revised]
PHST- 2023/06/07 00:00 [accepted]
PHST- 2023/08/09 06:43 [medline]
PHST- 2023/06/18 01:07 [pubmed]
PHST- 2023/06/17 18:02 [entrez]
AID - S0021-9673(23)00368-0 [pii]
AID - 10.1016/j.chroma.2023.464142 [doi]
PST - ppublish
SO  - J Chromatogr A. 2023 Aug 30;1705:464142. doi: 10.1016/j.chroma.2023.464142. Epub 
      2023 Jun 11.