PMID- 37330570
OWN - NLM
STAT- MEDLINE
DCOM- 20230619
LR  - 20231122
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Jun 17
TI  - Associations between intrinsic capacity, functional difficulty, and fall outcomes 
      among older adults in India.
PG  - 9829
LID - 10.1038/s41598-023-37097-x [doi]
LID - 9829
AB  - The construct of intrinsic capacity (IC) in the context of integrated care for 
      older adults emphasizes functional assessment from a holistic perspective. It 
      provides reliable and comparable insights on subsequent functioning and 
      disability. Given the paucity of research on IC and health outcomes in low- and 
      middle-income countries (LMICs), the present study examined the association of IC 
      with geriatric conditions of functional limitations and multiple fall outcomes 
      among older adults in India. The data used for analysis come from the first wave 
      of the Longitudinal Aging Study in India (LASI), 2017-2018. The final sample size 
      contains 24,136 older adults (11,871 males and 12,265 females) age 60 years or 
      above. Multivariable binary logistic regression is employed to examine the 
      association of IC and other explanatory factors with outcome variables of 
      difficulty in activities of daily living (ADL) and instrumental activities of 
      daily living (IADL), falls, fall injury, and multiple falls. Of the total sample, 
      24.56% of older adults were observed to be in the high IC category. The 
      prevalence of ADL difficulty, IADL difficulty, falls, multiple falls and 
      fall-related injury is estimated to be 19.89%, 45.00%, 12.36%, 5.49% and 5.57%, 
      respectively. Older adults who reported high IC had a significantly lower 
      prevalence of ADL difficulty (12.26% vs 22.38%) and IADL difficulty (31.13% vs 
      49.52%) than those who reported low IC. Similarly, a lower prevalence of falls 
      (9.42% vs 13.34%), fall-related injury (4.10% vs 6.06%) and multiple falls (3.46% 
      vs 6.16%) were reported among those who had high IC. After adjusting for a large 
      number of confounders such as age, sex, health-related attributes and lifestyle 
      behaviors, older adults with high IC had significantly lower odds of ADL 
      difficulty [aOR: 0.63, CI: 0.52-0.76], IADL difficulty [aOR: 0.71, CI: 
      0.60-0.83], falls [aOR: 0.80, CI: 0.67-0.96], multiple falls [aOR: 0.73, CI: 
      0.58-0.96] and fall-related injury [aOR: 0.78, CI: 0.61-0.99]. That a high IC was 
      independently associated with a lower risk of functional difficulty and fall 
      outcomes in later life is of enormous value in predicting subsequent functional 
      care needs. More specifically, the findings here imply that because regular IC 
      monitoring can predict poor health outcomes in older adults, improvements in IC 
      should be prioritized while formulating disability and fall prevention 
      strategies.
CI  - (c) 2023. The Author(s).
FAU - Muneera, K
AU  - Muneera K
AD  - National Institute of Technology, Calicut, Kerala, 673601, India.
FAU - Muhammad, T
AU  - Muhammad T
AUID- ORCID: 0000-0003-1486-7038
AD  - International Institute for Population Sciences, Mumbai, Maharashtra, 400088, 
      India. muhammad.iips@gmail.com.
FAU - Pai, Manacy
AU  - Pai M
AUID- ORCID: 0000-0003-3608-3859
AD  - Department of Sociology and Criminology, Kent State University, Kent, OH, 44242, 
      USA.
FAU - Ahmed, Waquar
AU  - Ahmed W
AD  - School of Health Systems Studies, Tata Institute of Social Sciences, Mumbai, 
      India.
FAU - Althaf, S
AU  - Althaf S
AD  - National Institute of Technology, Calicut, Kerala, 673601, India.
LA  - eng
GR  - R01 AG030153/AG/NIA NIH HHS/United States
GR  - R01 AG042778/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20230617
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Aged
MH  - Middle Aged
MH  - *Activities of Daily Living
MH  - Longitudinal Studies
MH  - Aging
MH  - *Disabled Persons
MH  - India/epidemiology
PMC - PMC10276857
COIS- The authors declare no competing interests.
EDAT- 2023/06/18 01:07
MHDA- 2023/06/19 13:08
PMCR- 2023/06/17
CRDT- 2023/06/17 23:21
PHST- 2023/01/29 00:00 [received]
PHST- 2023/06/15 00:00 [accepted]
PHST- 2023/06/19 13:08 [medline]
PHST- 2023/06/18 01:07 [pubmed]
PHST- 2023/06/17 23:21 [entrez]
PHST- 2023/06/17 00:00 [pmc-release]
AID - 10.1038/s41598-023-37097-x [pii]
AID - 37097 [pii]
AID - 10.1038/s41598-023-37097-x [doi]
PST - epublish
SO  - Sci Rep. 2023 Jun 17;13(1):9829. doi: 10.1038/s41598-023-37097-x.