PMID- 37335364
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230701
IS  - 2090-911X (Electronic)
IS  - 1110-2608 (Print)
IS  - 1110-2608 (Linking)
VI  - 75
IP  - 1
DP  - 2023 Jun 19
TI  - Impact of pulmonary valve replacement on left and right ventricular function 
      using strain analysis, in children with repaired tetralogy of Fallot.
PG  - 51
LID - 10.1186/s43044-023-00379-w [doi]
LID - 51
AB  - BACKGROUND: In repaired Tetralogy of Fallot (rTOF), pulmonary regurgitation and 
      resulting right ventricular (RV) and left ventricular (LV) dysfunction are 
      associated with adverse clinical outcomes. We performed an echocardiographic 
      assessment of LV and RV function using Global Longitudinal Strain (GLS) and 
      conventional echo method prior to and following Pulmonary Valvular Replacement 
      (PVR) to help inform proper timing of operation. RESULTS: A total of 30 rTOF 
      patients (12.17 +/- 2.5 years, 70% male) were included. Regarding to LV function, 
      the study revealed a significant reverse correlation between LV GLS (absolute 
      value) and early (mean = 10.4 days) and late (mean = 7.4 months) postop LVEF. 
      Paired T-Test showed significant difference between GLS of LV and RV before and 
      late after operation (op), however, without significant changes early postop. 
      Late postop significant improvements occurred in other conventional echo indices 
      of LV and RV function as well. There was also a significant correlation between 
      echo-measured LVEF & Fraction Area Change (RV FAC) and MRI-derived LVEF & RVEF, 
      respectively. CONCLUSION: In this cross-sectional study in rTOF patients, RV and 
      LV GLS as well as conventional echocardiographic indices regarding LV and RV 
      function improved significantly after 6 months (mean = 7.4mo) following PVR.
CI  - (c) 2023. The Author(s).
FAU - Moradian, Maryam
AU  - Moradian M
AUID- ORCID: 0000-0002-6642-0281
AD  - Department of Pediatric Cardiology, Rajaei Cardiovascular Research and Medical 
      Center, School of Medicine, Iran University of Medical Sciences, Intersection of 
      Niayesh Highway and Valiasr St, Tehran, 1995614331, Iran.
FAU - Rashidighader, Fariba
AU  - Rashidighader F
AUID- ORCID: 0000-0001-7813-5675
AD  - Department of Pediatric Cardiology, Rajaei Cardiovascular Research and Medical 
      Center, School of Medicine, Iran University of Medical Sciences, Intersection of 
      Niayesh Highway and Valiasr St, Tehran, 1995614331, Iran. frashidig90@gmail.com.
FAU - Golchinnaghash, Fatemeh
AU  - Golchinnaghash F
AUID- ORCID: 0000-0002-2588-7555
AD  - Department of Pediatric Cardiology, Rajaei Cardiovascular Research and Medical 
      Center, School of Medicine, Iran University of Medical Sciences, Intersection of 
      Niayesh Highway and Valiasr St, Tehran, 1995614331, Iran.
FAU - Meraji, Mahmoud
AU  - Meraji M
AD  - Department of Pediatric Cardiology, Rajaei Cardiovascular Research and Medical 
      Center, School of Medicine, Iran University of Medical Sciences, Intersection of 
      Niayesh Highway and Valiasr St, Tehran, 1995614331, Iran.
FAU - Ghaemi, Hamid Reza
AU  - Ghaemi HR
AUID- ORCID: 0000-0003-2608-2457
AD  - Department of Pediatric Cardiology, Rajaei Cardiovascular Research and Medical 
      Center, School of Medicine, Iran University of Medical Sciences, Intersection of 
      Niayesh Highway and Valiasr St, Tehran, 1995614331, Iran.
LA  - eng
PT  - Journal Article
DEP - 20230619
PL  - Germany
TA  - Egypt Heart J
JT  - The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of 
      Cardiology
JID - 9106952
PMC - PMC10279607
OTO - NOTNLM
OT  - Echocardiography
OT  - Pulmonary valve incompetence
OT  - Tetralogy of Fallot
COIS- All the authors declare that they surely have no any potential or perceived 
      financial and non-financial competing interests.
EDAT- 2023/06/19 13:08
MHDA- 2023/06/19 13:09
PMCR- 2023/06/19
CRDT- 2023/06/19 11:06
PHST- 2022/10/26 00:00 [received]
PHST- 2023/06/10 00:00 [accepted]
PHST- 2023/06/19 13:09 [medline]
PHST- 2023/06/19 13:08 [pubmed]
PHST- 2023/06/19 11:06 [entrez]
PHST- 2023/06/19 00:00 [pmc-release]
AID - 10.1186/s43044-023-00379-w [pii]
AID - 379 [pii]
AID - 10.1186/s43044-023-00379-w [doi]
PST - epublish
SO  - Egypt Heart J. 2023 Jun 19;75(1):51. doi: 10.1186/s43044-023-00379-w.