PMID- 37340210 OWN - NLM STAT- MEDLINE DCOM- 20240123 LR - 20240131 IS - 1559-0720 (Electronic) IS - 0163-4984 (Linking) VI - 202 IP - 3 DP - 2024 Mar TI - The Association Between Essential Metal Element Mixture and Sleep Quality in Chinese Community-Dwelling Older Adults. PG - 900-912 LID - 10.1007/s12011-023-03729-6 [doi] AB - Previous studies have related single essential metal elements (EMEs) to sleep quality among older adults, however, the association of the EME mixture with sleep quality remained poorly understood. This study aimed to investigate the relationships between single EMEs and the EME mixture and sleep quality in older adults living in Chinese communities. This study consisted of 3957 older adults aged 60 years or over. Urinary concentrations of cobalt (Co), vanadium (V), selenium (Se), molybdenum (Mo), strontium (Sr), calcium (Ca), and magnesium (Mg) were detected using inductively coupled plasma mass spectrometry. Sleep quality was evaluated using Pittsburgh Sleep Quality Index (PSQI). The associations of single EMEs and EME mixture with sleep quality were assessed using logistic regression and Bayesian kernel machine regression (BKMR) models, respectively. Adjusted single-element logistic regression models showed that Mo (OR = 0.927, 95%CI:0.867-0.990), Sr (OR = 0.927, 95%CI:0.864-0.994), and Mg (OR = 0.934, 95%CI:0.873-0.997) were negatively related to poor sleep quality. BKMR models exhibited similar results. Also, higher levels of the EME mixture in urine were inversely related to the odds of poor sleep quality after adjustment for covariates, and Mo had the largest conditional posterior inclusion probability (condPIP) value in the mixture. Mo, Sr, and Mg were negatively related to poor sleep quality, separately and as the mixture. The EME mixture in urine was associated with decreased odds of poor sleep quality in older adults, and Mo was the greatest contributor within the mixture. Additional cohort research is warranted to clarify the relationship of multiple EMEs with sleep quality. CI - (c) 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. FAU - Wang, Hongli AU - Wang H AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. FAU - Zhang, Yan AU - Zhang Y AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. FAU - Li, Huaibiao AU - Li H AD - Fuyang Center for Diseases Prevention and Control, Fuyang, 236069, Anhui, China. FAU - Li, Junzhe AU - Li J AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. FAU - Liu, Qiang AU - Liu Q AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. FAU - Wang, Yuan AU - Wang Y AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. FAU - Sun, Liang AU - Sun L AD - Fuyang Center for Diseases Prevention and Control, Fuyang, 236069, Anhui, China. FAU - Hu, Bing AU - Hu B AD - Fuyang Center for Diseases Prevention and Control, Fuyang, 236069, Anhui, China. FAU - Chen, Guimei AU - Chen G AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. AD - School of Health Services Management, Anhui Medical University, Hefei, 230032, Anhui, China. FAU - Zhang, Dongmei AU - Zhang D AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. AD - School of Health Services Management, Anhui Medical University, Hefei, 230032, Anhui, China. FAU - Liang, Chunmei AU - Liang C AD - School of Public Health, Department of Hygiene Inspection and Quarantine, Anhui Medical University, Hefei, 230032, Anhui, China. AD - Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, Hefei, 230032, Anhui, China. AD - NHC Key Laboratory of Study On Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, 230032, Anhui, China. FAU - Lei, Jingyuan AU - Lei J AD - School of Public Health, Department of Hygiene Inspection and Quarantine, Anhui Medical University, Hefei, 230032, Anhui, China. FAU - Wang, Panpan AU - Wang P AD - School of Public Health, Department of Hygiene Inspection and Quarantine, Anhui Medical University, Hefei, 230032, Anhui, China. FAU - Tao, Fangbiao AU - Tao F AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. AD - Key Laboratory of Population Health Across Life Cycle, Anhui Medical University, Ministry of Education of the People's Republic of China, Hefei, 230032, Anhui, China. FAU - Yang, Linsheng AU - Yang L AD - School of Public Health, Department of Epidemiology and Health Statistics, Anhui Medical University, Meishan Road 81, Hefei, 230032, Anhui, China. yanglinsheng@ahmu.edu.cn. AD - Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, 230032, Anhui, China. yanglinsheng@ahmu.edu.cn. LA - eng GR - 0303011224/Fangbiao Tao/ GR - KJ2017A189, Xj201525, 2017062, 2018160/Linsheng Yang/ PT - Journal Article DEP - 20230620 PL - United States TA - Biol Trace Elem Res JT - Biological trace element research JID - 7911509 RN - 81AH48963U (Molybdenum) RN - YZS2RPE8LE (Strontium) RN - I38ZP9992A (Magnesium) SB - IM MH - Humans MH - Aged MH - *Sleep Quality MH - Bayes Theorem MH - Independent Living MH - Molybdenum MH - Strontium MH - *Sleep Initiation and Maintenance Disorders MH - Magnesium MH - China OTO - NOTNLM OT - BKMR OT - Essential Metal Elements OT - Older Adults OT - Sleep Quality EDAT- 2023/06/21 01:07 MHDA- 2024/01/23 06:43 CRDT- 2023/06/20 23:30 PHST- 2023/04/28 00:00 [received] PHST- 2023/06/10 00:00 [accepted] PHST- 2024/01/23 06:43 [medline] PHST- 2023/06/21 01:07 [pubmed] PHST- 2023/06/20 23:30 [entrez] AID - 10.1007/s12011-023-03729-6 [pii] AID - 10.1007/s12011-023-03729-6 [doi] PST - ppublish SO - Biol Trace Elem Res. 2024 Mar;202(3):900-912. doi: 10.1007/s12011-023-03729-6. Epub 2023 Jun 20.