PMID- 37340230 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230801 IS - 1869-6953 (Print) IS - 1869-6961 (Electronic) IS - 1869-6961 (Linking) VI - 14 IP - 9 DP - 2023 Sep TI - Perceived Future Outcomes of Unsuccessful Treatment and Their Association with Treatment Persistence Among Type-2 Diabetes Patients: A Cross-Sectional Content Analysis. PG - 1437-1449 LID - 10.1007/s13300-023-01433-1 [doi] AB - INTRODUCTION: Despite the known strong association between patients' knowledge of outcomes of type 2 diabetes mellitus (T2DM) and treatment persistence, this knowledge in this patient population requires further clarification. The aim of our study was to reveal the perception of unsuccessful treatment outcomes among patients with T2DM and its association with treatment persistence by analysing answers to open-ended questions. METHODS: In this cross-sectional study, 106 patients with T2DM who lived in Fukushima Prefecture, Japan, had a medical record in the Fukushima National Health Insurance Organisation database and had no cognitive problems were enrolled by purposive sampling. Treatment status was defined as "non-persistent" when a participant's treatment medical record was absent for a continuous period of >/= 6 months; otherwise, it was referred to as "persistent". We asked about the possible future problems of untreated T2DM, inductively classified the open answers into 15 codes and then statistically examined the association between these codes and treatment persistence using logistic regression analysis adjusted for age and sex. RESULTS: Persistent treatment was prevalent among participants who mentioned the code "treatment", which encompasses the terms that indicated invasiveness, such as dialysis, insulin injection, and shots (odds ratio 4.339; 95% confidence interval 1.104-17.055). CONCLUSION: Persistent treatment was prevalent among patients with T2DM who mentioned the code "treatment", suggesting that these patients may anticipate a threat due to the invasiveness of diabetes and thus participate in persistent treatment to avoid this threat. Healthcare professionals should provide appropriate information and supportive conditions to achieve both a reduced feeling of threat and persistent treatment engagement. CI - (c) 2023. The Author(s). FAU - Hidaka, Tomoo AU - Hidaka T AUID- ORCID: 0000-0003-2987-4804 AD - Department of Hygiene and Preventive Medicine, Fukushima Medical University, Hikarigaoka 1, Fukushima, Fukushima, 9601295, Japan. thidaka@fmu.ac.jp. FAU - Suzuki, Rieko AU - Suzuki R AD - Koriyama City Public Health Center, 15-1, Asahi 2, Koriyama, Fukushima, 9638024, Japan. FAU - Hashimoto, Katsue AU - Hashimoto K AD - Koriyama City Public Health Center, 15-1, Asahi 2, Koriyama, Fukushima, 9638024, Japan. FAU - Inoue, Mariko AU - Inoue M AD - CMR Development Division, Novo Nordisk Pharma Ltd., 2-1-1, Marunouchi, Chiyoda-ku, Tokyo, 1000005, Japan. FAU - Terada, Yukiko AU - Terada Y AD - CMR Development Division, Novo Nordisk Pharma Ltd., 2-1-1, Marunouchi, Chiyoda-ku, Tokyo, 1000005, Japan. FAU - Endo, Shota AU - Endo S AD - Department of Hygiene and Preventive Medicine, Fukushima Medical University, Hikarigaoka 1, Fukushima, Fukushima, 9601295, Japan. FAU - Kakamu, Takeyasu AU - Kakamu T AD - Department of Hygiene and Preventive Medicine, Fukushima Medical University, Hikarigaoka 1, Fukushima, Fukushima, 9601295, Japan. FAU - Gunji, Mariko AU - Gunji M AD - Koriyama City Public Health Center, 15-1, Asahi 2, Koriyama, Fukushima, 9638024, Japan. FAU - Abe, Koichi AU - Abe K AD - Igarashi Clinic of Medicine and Surgery, 12-7, Namiki 2, Koriyama, Fukushima, 9638026, Japan. FAU - Fukushima, Tetsuhito AU - Fukushima T AD - Department of Hygiene and Preventive Medicine, Fukushima Medical University, Hikarigaoka 1, Fukushima, Fukushima, 9601295, Japan. LA - eng PT - Journal Article DEP - 20230620 PL - United States TA - Diabetes Ther JT - Diabetes therapy : research, treatment and education of diabetes and related disorders JID - 101539025 PMC - PMC10363091 OTO - NOTNLM OT - Content analysis OT - Fear-based strategy OT - Future perspective OT - Invasiveness OT - Persistent treatment OT - Psychological insulin resistance OT - Text-mining COIS- Mariko Inoue and Yukiko Terada have been employed by and had a stock ownership of Novo Nordisk Pharma Ltd. Tomoo Hidaka, Rieko Suzuki, Katsue Hashimoto, Shota Endo, Takeyasu Kakamu, Mariko Gunji, Koicko Abe, and Tetsuhito Fukushima declare that they have no conflict of interest. EDAT- 2023/06/21 01:07 MHDA- 2023/06/21 01:08 PMCR- 2023/06/20 CRDT- 2023/06/20 23:31 PHST- 2023/04/26 00:00 [received] PHST- 2023/06/07 00:00 [accepted] PHST- 2023/06/21 01:08 [medline] PHST- 2023/06/21 01:07 [pubmed] PHST- 2023/06/20 23:31 [entrez] PHST- 2023/06/20 00:00 [pmc-release] AID - 10.1007/s13300-023-01433-1 [pii] AID - 1433 [pii] AID - 10.1007/s13300-023-01433-1 [doi] PST - ppublish SO - Diabetes Ther. 2023 Sep;14(9):1437-1449. doi: 10.1007/s13300-023-01433-1. Epub 2023 Jun 20.