PMID- 37343326
OWN - NLM
STAT- MEDLINE
DCOM- 20230821
LR  - 20230823
IS  - 1873-6750 (Electronic)
IS  - 0160-4120 (Linking)
VI  - 178
DP  - 2023 Aug
TI  - Multi-dimensional visualization of ingestion, biological effects and interactions 
      of microplastics and a representative POP in edible jellyfish.
PG  - 108028
LID - S0160-4120(23)00301-X [pii]
LID - 10.1016/j.envint.2023.108028 [doi]
AB  - Due to their ubiquity and potential risks, microplastics (MPs) and nanoplastics 
      (NPs) are concerning environmental issues. Yet there are still significant 
      knowledge gaps in understanding the tissue-specific accumulation and dynamic 
      change of MPs and NPs in the aquatic organism and how these micro/nano-scale 
      emerging contaminants interact with other environmental pollutants such as 
      persistent organic pollutants (POPs). Here, in vivo imaging systems (IVIS), 
      radioisotope tracing, and histological staining were innovatively used to reveal 
      the fate and toxicity of fluorescently-labeled MPs/NPs and (14)C-labeled 
      2,4,4'-trichlorobiphenyl (PCB28) in edible jellyfish Rhopilema esculentum. These 
      contaminants' ingestion, biological effects, and interactions were visualized at 
      cellular, tissue, and whole-body multidimensional levels. Both MPs and NPs were 
      shown to be preferentially accumulated in the mouthlets of oral arms, and most 
      ingested MPs/NPs were present in the extracellular environment instead of being 
      internalized into the mesoglea. Moreover, the presence of MPs or NPs in the 
      seawater significantly inhibited the bioaccumulation of PCB28 in the jellyfish 
      tissue, thus alleviating physiological alteration, gastric damage, and apoptosis 
      caused by PCB28. This study provides a multi-dimensional visualization strategy 
      to display the distribution and biological effects of typical pollutants in 
      marine organisms and offers new insights for understanding the impacts of MPs/NPs 
      and POPs on marine ecosystems.
CI  - Copyright (c) 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.
FAU - Hu, Jirong
AU  - Hu J
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Ye, Feiyang
AU  - Ye F
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Zhang, Sufen
AU  - Zhang S
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Li, Hao
AU  - Li H
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Bao, Qian
AU  - Bao Q
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Gan, Jay
AU  - Gan J
AD  - Department of Environmental Sciences, University of California, Riverside, CA 
      92521, USA.
FAU - Ye, Qingfu
AU  - Ye Q
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China.
FAU - Wang, Wei
AU  - Wang W
AD  - Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear 
      Agricultural Sciences of Ministry of Agriculture of PRC and Zhejiang Province, 
      Zhejiang University, Hangzhou 310058, China. Electronic address: 
      wei_wang@zju.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230613
PL  - Netherlands
TA  - Environ Int
JT  - Environment international
JID - 7807270
RN  - 0 (Microplastics)
RN  - 0 (Plastics)
RN  - 0 (Water Pollutants, Chemical)
RN  - 0 (Environmental Pollutants)
SB  - IM
MH  - Microplastics/toxicity
MH  - Plastics/toxicity
MH  - Ecosystem
MH  - *Water Pollutants, Chemical/toxicity/analysis
MH  - *Environmental Pollutants
MH  - Aquatic Organisms
MH  - Eating
OTO - NOTNLM
OT  - Autoradiography
OT  - Fluorescence imaging
OT  - Jellyfish
OT  - Microplastics
OT  - Nanoplastics
OT  - Persistent organic pollutant
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/06/22 01:07
MHDA- 2023/08/21 06:42
CRDT- 2023/06/21 18:00
PHST- 2023/02/07 00:00 [received]
PHST- 2023/05/05 00:00 [revised]
PHST- 2023/06/08 00:00 [accepted]
PHST- 2023/08/21 06:42 [medline]
PHST- 2023/06/22 01:07 [pubmed]
PHST- 2023/06/21 18:00 [entrez]
AID - S0160-4120(23)00301-X [pii]
AID - 10.1016/j.envint.2023.108028 [doi]
PST - ppublish
SO  - Environ Int. 2023 Aug;178:108028. doi: 10.1016/j.envint.2023.108028. Epub 2023 
      Jun 13.