PMID- 37344538
OWN - NLM
STAT- MEDLINE
DCOM- 20230623
LR  - 20230701
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Jun 21
TI  - Left atrial function index predicts poor outcome in STEMI patients treated with 
      percutaneous coronary intervention.
PG  - 10109
LID - 10.1038/s41598-023-33257-1 [doi]
LID - 10109
AB  - The prognostic value of the left atrial function index (LAFI) in acute ST segment 
      elevation myocardial infarction (STEMI) patients treated with percutaneous 
      coronary intervention (PCI) is unknown. This study sought to determine whether 
      the LAFI predicts prognosis in STEMI patients treated with PCI. Patients with 
      newly diagnosed STEMI who were treated with PCI in Hunan Provincial People's 
      Hospital from March 2020 to October 2020 were prospectively enrolled. All 
      patients underwent transthoracic echocardiography at baseline and follow-up. The 
      endpoint events included rehospitalization due to unstable angina, nonfatal 
      myocardial infarction, rehospitalization due to heart failure and cardiovascular 
      death. A total of 156 STEMI patients treated with PCI were studied with a median 
      follow-up of 14 months. Forty-eight patients had endpoint events. The LAFI had 
      the highest area under the receiver operating characteristic curve (AUC) 
      predicting the endpoint events, with an AUC of 0.90 (95% CI 0.84-0.94). 
      Multivariate Cox analysis demonstrated that only the LAFI (HR: 0.91, 95% CI 
      0.87-0.96, P < 0.0001) was independently predictive of endpoint events. 
      Kaplan‒Meier survival curves showed that patients with an LAFI </= 42.25 cm/cc/m(2) 
      had more events than patients with an LAFI > 42.25 cm/cc/m(2) (HR: 19.15, 95% CI 
      8.90-41.21, P < 0.001). The LAFI is a strong and independent predictor of events 
      in STEMI patients treated with PCI.
CI  - (c) 2023. The Author(s).
FAU - Tang, Yi
AU  - Tang Y
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Huang, Pei
AU  - Huang P
AD  - Department of Cardiology, Changsha Hospital of Traditional Chinese Medicine 
      (Changsha Eighth Hospital), Changsha, 410199, Hunan, China.
FAU - Liu, Zhibin
AU  - Liu Z
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Tang, Yijin
AU  - Tang Y
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Liu, Wei
AU  - Liu W
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - She, Chang
AU  - She C
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Zhong, Changqing
AU  - Zhong C
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Pei, Jianqiang
AU  - Pei J
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China.
FAU - Fu, Qinghua
AU  - Fu Q
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China. qing_hua2001@aliyun.com.
FAU - Zhang, Liang
AU  - Zhang L
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China. iarry@sina.com.
FAU - Zhang, Yi
AU  - Zhang Y
AD  - Department of Cardiology, Hunan Provincial People's Hospital, The First 
      Affiliated Hospital of Hunan Normal University, Clinical Medicine Research Center 
      of Heart Failure of Hunan Province, Hunan Normal University, Changsha, 410005, 
      China. zhangyi3@medmail.com.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230621
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Humans
MH  - *ST Elevation Myocardial Infarction/diagnostic imaging/surgery
MH  - *Percutaneous Coronary Intervention/adverse effects
MH  - Atrial Function, Left
MH  - Retrospective Studies
MH  - *Myocardial Infarction/etiology
MH  - Prognosis
MH  - Treatment Outcome
PMC - PMC10284795
COIS- The authors declare no competing interests.
EDAT- 2023/06/22 01:07
MHDA- 2023/06/23 06:42
PMCR- 2023/06/21
CRDT- 2023/06/21 23:20
PHST- 2022/08/13 00:00 [received]
PHST- 2023/04/10 00:00 [accepted]
PHST- 2023/06/23 06:42 [medline]
PHST- 2023/06/22 01:07 [pubmed]
PHST- 2023/06/21 23:20 [entrez]
PHST- 2023/06/21 00:00 [pmc-release]
AID - 10.1038/s41598-023-33257-1 [pii]
AID - 33257 [pii]
AID - 10.1038/s41598-023-33257-1 [doi]
PST - epublish
SO  - Sci Rep. 2023 Jun 21;13(1):10109. doi: 10.1038/s41598-023-33257-1.