PMID- 37345067 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230701 IS - 2072-6694 (Print) IS - 2072-6694 (Electronic) IS - 2072-6694 (Linking) VI - 15 IP - 10 DP - 2023 May 12 TI - The Role of Lumen Apposing Metal Stents in the Palliation of Distal Malignant Biliary Distal Obstruction. LID - 10.3390/cancers15102730 [doi] LID - 2730 AB - Malignant biliary obstruction (DMBO) has been traditionally managed by endoscopic retrograde cholangiopancreatography (ERCP). In the case of ERC failure, percutaneous transhepatic biliary drainage (PT-BD) has been widely utilized as a salvage procedure. However, over the last decade, endoscopic ultrasound-guided biliary drainage (EUS-BD) has gained increasing popularity, especially after the advent of electrocautery-enhanced lumen apposing metal stent devices (EC-LAMSs) which enable a one-step procedure, granting prevention of biliary leakage and minimizing occurrence of adverse events (AEs). In parallel, increasing evidence suggests a possible role of EUS-BD in the management of DMBO as a primary palliative drainage modality. In the current paper, we aim to review all the available evidence on the role of EUS-BD performed with EC-LAMSs and discuss salient technical aspects of this type of procedure. FAU - Voiosu, Theodor Alexandru AU - Voiosu TA AD - Carol Davila Faculty of Medicine, 021155 Bucharest, Romania. AD - Gastroenterology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania. FAU - Rimbas, Mihai AU - Rimbas M AD - Carol Davila Faculty of Medicine, 021155 Bucharest, Romania. AD - Gastroenterology Department, Colentina Clinical Hospital, 020125 Bucharest, Romania. FAU - Larghi, Alberto AU - Larghi A AD - Digestive Endoscopy Unit, Scientific Institute for Research, Hospitalization, and Health Care, Fondazione Policlinico Universitario A. Gemelli, Catholic University, 00168 Rome, Italy. LA - eng PT - Journal Article PT - Review DEP - 20230512 PL - Switzerland TA - Cancers (Basel) JT - Cancers JID - 101526829 PMC - PMC10216748 OTO - NOTNLM OT - biliary obstruction OT - endoscopic ultrasonography OT - lumen apposing metal stents (LAMS) COIS- AL-Consultant for Boston Scientific Corp. (Marlborough, MA, USA), Pentax Medical, M.I. Tech, Teaching fee from Taewong Medical, Research support from Medtronic. The remaining authors declare no conflict of interest. EDAT- 2023/06/22 06:42 MHDA- 2023/06/22 06:43 PMCR- 2023/05/12 CRDT- 2023/06/22 01:00 PHST- 2023/04/08 00:00 [received] PHST- 2023/05/03 00:00 [revised] PHST- 2023/05/08 00:00 [accepted] PHST- 2023/06/22 06:43 [medline] PHST- 2023/06/22 06:42 [pubmed] PHST- 2023/06/22 01:00 [entrez] PHST- 2023/05/12 00:00 [pmc-release] AID - cancers15102730 [pii] AID - cancers-15-02730 [pii] AID - 10.3390/cancers15102730 [doi] PST - epublish SO - Cancers (Basel). 2023 May 12;15(10):2730. doi: 10.3390/cancers15102730.