PMID- 37353899
OWN - NLM
STAT- MEDLINE
DCOM- 20230801
LR  - 20230801
IS  - 1532-7914 (Electronic)
IS  - 0163-5581 (Linking)
VI  - 75
IP  - 8
DP  - 2023
TI  - The Evaluation of Dietary Antioxidant Capacity, Dietary Inflammatory Index and 
      Serum Biomarkers in Breast Cancer: A Prospective Study.
PG  - 1625-1637
LID - 10.1080/01635581.2023.2227404 [doi]
AB  - Dietary antioxidant capacity (dTAC) and dietary inflammatory index (DII) are 
      commonly used to assess nutrition. This prospective study examined dTAC, DII, and 
      serum biomarkers in women with breast cancer (BC). Patients were followed-up 
      before surgery (T(1)), before chemotherapy (T(2)), at 6(th) (T(3)) and 12(th) 
      months of chemotherapy (T(4)). Serum tumor necrosis factor alpha, interleukin 1beta, 
      interleukin 6, protein carbonyl, malondialdehyde, total antioxidant capacity 
      (TAC), and total oxidant status levels were analyzed. Dietary antioxidant intake, 
      dTAC, and DII were determined using a three-day dietary record. dTAC was 
      calculated using vitamin C equivalent (VCE), oxygen radical absorption capacity 
      (ORAC), trolox equivalent antioxidant capacity (TEAC), total radical-trapping 
      antioxidant parameter (TRAP), and ferrous ion reducing antioxidant potential 
      (FRAP). This study included 32 women with BC and 32 controls (CG). ORAC, TEAC, 
      TRAP, and FRAP were significantly lower in BC than in CG. During follow-up, only 
      ORAC increased significantly at T(2) compared to T(1). A weak positive 
      correlation was found between dTAC (VCE) and serum TAC levels at T(2) (rho = 
      0.371, p = 0.036). The relationship between diet and serum biomarkers was not 
      significant. Multicenter prospective studies on different age groups are needed 
      to understand the association between diet and serum biomarkers levels in 
      patients with BC.
FAU - Alkan, Senay Burcin
AU  - Alkan SB
AD  - Department of Nutrition and Dietetics, Nezahat Kelesoglu Faculty of Health 
      Sciences, Necmettin Erbakan University, Konya, Turkey.
FAU - Artac, Mehmet
AU  - Artac M
AD  - Department of Medical Oncology, Meram Faculty of Medicine, Necmettin Erbakan 
      University, Konya, Turkey.
FAU - Aksoy, Faruk
AU  - Aksoy F
AD  - Department of General Surgery, Trabzon Kanuni Training and Research Hospital, 
      University of Health Sciences, Trabzon, Turkey.
FAU - Belviranli, Mehmet Metin
AU  - Belviranli MM
AD  - Department of General Surgery, Meram Faculty of Medicine, Necmettin Erbakan 
      University, Konya, Turkey.
FAU - Gurbilek, Mehmet
AU  - Gurbilek M
AD  - Department of Biochemistry, Meram Faculty of Medicine, Necmettin Erbakan 
      University, Konya, Turkey.
FAU - Akay Cizmecioglu, Hilal
AU  - Akay Cizmecioglu H
AD  - Department of Internal Medicine, Meram Faculty of Medicine, Necmettin Erbakan 
      University, Konya, Turkey.
FAU - Rakicioglu, Neslisah
AU  - Rakicioglu N
AD  - Department of Nutrition and Dietetics, Faculty of Health Sciences, Hacettepe 
      University, Ankara, Turkey.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20230623
PL  - United States
TA  - Nutr Cancer
JT  - Nutrition and cancer
JID - 7905040
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - PQ6CK8PD0R (Ascorbic Acid)
RN  - 0 (Vitamins)
SB  - IM
MH  - Humans
MH  - Female
MH  - *Antioxidants/metabolism
MH  - Prospective Studies
MH  - *Breast Neoplasms
MH  - Diet
MH  - Biomarkers
MH  - Ascorbic Acid
MH  - Vitamins
EDAT- 2023/06/24 11:42
MHDA- 2023/08/01 06:45
CRDT- 2023/06/24 01:03
PHST- 2023/08/01 06:45 [medline]
PHST- 2023/06/24 11:42 [pubmed]
PHST- 2023/06/24 01:03 [entrez]
AID - 10.1080/01635581.2023.2227404 [doi]
PST - ppublish
SO  - Nutr Cancer. 2023;75(8):1625-1637. doi: 10.1080/01635581.2023.2227404. Epub 2023 
      Jun 23.