PMID- 37357744
OWN - NLM
STAT- Publisher
LR  - 20230915
IS  - 2369-5293 (Electronic)
IS  - 0825-8597 (Linking)
DP  - 2023 Jun 26
TI  - Effectiveness of Timely Implementation of Palliative Care on the Well-Being of 
      Patients With Chronic Heart Failure: A Randomized Case-Control Study.
PG  - 8258597231184798
LID - 10.1177/08258597231184798 [doi]
AB  - Objectives: To date, there is a lack of consensus on the timely implementation of 
      palliative care (PC) in patients with chronic heart failure (HF). We aimed to 
      investigate the impact of primary PC intervention on chronic HF patients with 
      different classes of cardiac function, and to determine a proper time point for 
      the implementation of primary PC intervention. Methods: A consecutive series of 
      180 chronic HF patients with the New York Heart Association (NYHA) Cardiac 
      function ranging from I to III were enrolled in this study. Patients with the 
      same cardiac function class, they were randomized and equally assigned to the 
      usual care (UC) group or to the PC intervention group. At the end of 24-week 
      treatment, quality-of-life (QoL) measurements were evaluated. Left ventricular 
      ejection fraction and N-terminal pro-B-type natriuretic peptide were measured for 
      each group at baseline and the final follow-up, respectively. Results: Through 
      the 6-month follow-up, patients randomized to the PC intervention group presented 
      significantly better QoL and cardiac function as compared with patients 
      randomized to the UC group alone. Subgroup analysis showed that for patients with 
      NYHA class II or III, significantly improved cardiac function and QoL were 
      observed in the PC intervention group as compared with the control group. As for 
      patients with class I, no significant difference was found between the 2 groups. 
      Conclusions: Palliative program can effectively improve the QoL and cardiac 
      function of patients with chronic HF. Moreover, we provided evidence on timely 
      referral of patients to PC intervention, which could be beneficial for patients 
      with NYHA class II.
FAU - Pan, Lu
AU  - Pan L
AD  - Department of Geriatrics, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Nanjing, China. RINGGOLD: 66506
FAU - Qiao, Li
AU  - Qiao L
AD  - Department of Emergency, The Affiliated Drum Tower Hospital of Nanjing University 
      Medical School, Nanjing, China. RINGGOLD: 66506
FAU - Zhang, Yuzhe
AU  - Zhang Y
AD  - Department of Psychology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Nanjing, China. RINGGOLD: 66506
FAU - Zhang, Jianwei
AU  - Zhang J
AD  - Department of Geriatrics, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Nanjing, China. RINGGOLD: 66506
FAU - Yuan, Ling
AU  - Yuan L
AD  - Department of Nursing, The Affiliated Drum Tower Hospital of Nanjing University 
      Medical School, Nanjing, China. RINGGOLD: 66506
LA  - eng
PT  - Journal Article
DEP - 20230626
PL  - United States
TA  - J Palliat Care
JT  - Journal of palliative care
JID - 8610345
SB  - IM
OTO - NOTNLM
OT  - cardiac function
OT  - chronic heart failure
OT  - palliative care
OT  - psychometric property
OT  - quality of life
EDAT- 2023/06/26 06:41
MHDA- 2023/06/26 06:41
CRDT- 2023/06/26 04:33
PHST- 2023/06/26 06:41 [pubmed]
PHST- 2023/06/26 06:41 [medline]
PHST- 2023/06/26 04:33 [entrez]
AID - 10.1177/08258597231184798 [doi]
PST - aheadofprint
SO  - J Palliat Care. 2023 Jun 26:8258597231184798. doi: 10.1177/08258597231184798.