PMID- 37358653 OWN - NLM STAT- MEDLINE DCOM- 20230905 LR - 20230912 IS - 1434-4726 (Electronic) IS - 0937-4477 (Print) IS - 0937-4477 (Linking) VI - 280 IP - 10 DP - 2023 Oct TI - Evaluation of outcome of acoustic reflex tests in patients with type 2 diabetes mellitus: a cross-sectional study. PG - 4665-4675 LID - 10.1007/s00405-023-08065-y [doi] AB - PURPOSE: Type 2 diabetes mellitus (T2DM) may induce micro-vascular and macro-vascular changes that can lead to neuropathic changes which may affect the auditory pathway resulting in hearing loss. The study aims to evaluate the outcome of ipsilateral and contralateral acoustic reflex (AR) parameters and reflex decay tests (RDT) in patients with T2DM, and the relationship between average AR parameters, and duration and control of T2DM. METHODS: An analytical cross-sectional study was conducted in a tertiary care setup in 126 subjects which included 42 subjects with T2DM between 30 and 60 years of age, age-matched with 84 non-diabetic subjects. The subjects were evaluated for pure tone average (PTA), speech identification score (SIS), AR parameters [acoustic reflex threshold (ART), acoustic reflex amplitude (ARA), acoustic reflex latency (ARL)] and RDT. RESULTS: The subjects with T2DM showed increased PTA in both ears when compared to the subjects with no disease. No significant difference was found in the SIS between both groups. There was no significant difference in the ART and ARL between the two groups. There was a significant difference in the ipsilateral and contralateral ARA at 500 Hz, 1000 Hz and broadband noise (BBN) when compared between the diabetic and non-diabetic groups. No significant difference was found between average AR parameters and duration and control of T2DM. CONCLUSION: T2DM increases hearing thresholds and reduces ipsilateral and contralateral AR at lower frequencies and BBN. Duration and control of T2DM do not affect the AR parameters. CI - (c) 2023. The Author(s). FAU - Praneetha, Puvvula AU - Praneetha P AD - Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India. FAU - Dosemane, Deviprasad AU - Dosemane D AUID- ORCID: 0000-0001-6282-0029 AD - Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India. deviprasad.d@manipal.edu. FAU - Khadilkar, Meera Niranjan AU - Khadilkar MN AUID- ORCID: 0000-0002-2006-8913 AD - Department of Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India. FAU - Kumar, Kaushlendra AU - Kumar K AUID- ORCID: 0000-0001-6585-8081 AD - Department of Audiology and Speech Language Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India. FAU - Ebenezer, Anupriya AU - Ebenezer A AUID- ORCID: 0000-0002-0121-9392 AD - Department of Audiology and Speech Language Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, 575001, India. LA - eng PT - Journal Article DEP - 20230626 PL - Germany TA - Eur Arch Otorhinolaryngol JT - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery JID - 9002937 SB - IM MH - Humans MH - *Reflex, Acoustic MH - Cross-Sectional Studies MH - *Diabetes Mellitus, Type 2/complications/diagnosis MH - Auditory Threshold MH - Hearing MH - Acoustic Impedance Tests PMC - PMC10477216 OTO - NOTNLM OT - Acoustic reflex OT - Auditory pathways OT - Health OT - Pure tone audiometry OT - Type 2 diabetes mellitus COIS- The authors have no relevant financial or non-financial interests to disclose. EDAT- 2023/06/26 13:07 MHDA- 2023/09/05 06:42 PMCR- 2023/06/26 CRDT- 2023/06/26 11:08 PHST- 2023/03/10 00:00 [received] PHST- 2023/06/10 00:00 [accepted] PHST- 2023/09/05 06:42 [medline] PHST- 2023/06/26 13:07 [pubmed] PHST- 2023/06/26 11:08 [entrez] PHST- 2023/06/26 00:00 [pmc-release] AID - 10.1007/s00405-023-08065-y [pii] AID - 8065 [pii] AID - 10.1007/s00405-023-08065-y [doi] PST - ppublish SO - Eur Arch Otorhinolaryngol. 2023 Oct;280(10):4665-4675. doi: 10.1007/s00405-023-08065-y. Epub 2023 Jun 26.