PMID- 37365949 OWN - NLM STAT- MEDLINE DCOM- 20230703 LR - 20231218 IS - 2689-6591 (Electronic) VI - 41 IP - 1-2 DP - 2023 TI - Health risk assessment of exposure to triclosan in pregnant women using Monte Carlo simulation techniques: based on biomonitoring data. PG - 61-75 LID - 10.1080/26896583.2023.2226587 [doi] AB - This study aimed to assess the triclosan (TCS) health risk in an Iranian pregnant women sample by Monte Carlo simulation (MCS). The urinary TCS of 99 women after the 28(th) week of pregnancy was detected by gas chromatography/mass spectrometry detector (GC/MS), and the MCS model implemented a health risk assessment. The corresponding hazard quotient (HQ) and the sensitivity analysis were calculated. TCS was measured in 100% of the urine samples with a median concentration of 2.89 microg/L. The median of HQ was obtained at 1.93 x 10(-4). The TCS exposure risk in the studied population was lower than the allowable limit. A comparison between HQ values in the two weight subgroups of pregnant women showed that the risk level is almost equal, and there was minimal health risk in pregnant women from exposure to TCS. FAU - Attarian, Elham AU - Attarian E AUID- ORCID: 0000-0002-4100-0328 AD - Student Research Committee, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Mohammadi, Farzaneh AU - Mohammadi F AUID- ORCID: 0000-0002-8248-3629 AD - Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Environment Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Ebrahimpour, Karim AU - Ebrahimpour K AUID- ORCID: 0000-0002-6230-0119 AD - Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Environment Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Moazeni, Malihe AU - Moazeni M AUID- ORCID: 0000-0002-8335-8483 AD - Student Research Committee, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Maracy, Mohammadreza AU - Maracy M AD - Environment Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Ebrahimi, Afshin AU - Ebrahimi A AD - Department of Environmental Health Engineering, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran. AD - Environment Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. FAU - Kelishadi, Roya AU - Kelishadi R AD - Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230627 PL - United States TA - J Environ Sci Health C Toxicol Carcinog JT - Journal of environmental science and health. Part C, Toxicology and carcinogenesis JID - 101766761 RN - 4NM5039Y5X (Triclosan) SB - IM MH - Humans MH - Female MH - Pregnancy MH - *Triclosan MH - Pregnant Women MH - Biological Monitoring MH - Monte Carlo Method MH - Iran MH - Risk Assessment OTO - NOTNLM OT - Monte Carlo method OT - Triclosan OT - pharmaceutical preparations OT - pregnant women OT - risk assessment EDAT- 2023/06/27 06:42 MHDA- 2023/07/03 06:42 CRDT- 2023/06/27 03:34 PHST- 2023/07/03 06:42 [medline] PHST- 2023/06/27 06:42 [pubmed] PHST- 2023/06/27 03:34 [entrez] AID - 10.1080/26896583.2023.2226587 [doi] PST - ppublish SO - J Environ Sci Health C Toxicol Carcinog. 2023;41(1-2):61-75. doi: 10.1080/26896583.2023.2226587. Epub 2023 Jun 27.