PMID- 37366805
OWN - NLM
STAT- MEDLINE
DCOM- 20230629
LR  - 20230701
IS  - 2543-6031 (Electronic)
IS  - 2451-4934 (Print)
IS  - 2451-4934 (Linking)
VI  - 91
IP  - 3
DP  - 2023 Jun 7
TI  - Effect of Hydration on Pulmonary Function and Development of Exercise-Induced 
      Bronchoconstriction among Professional Male Cyclists.
PG  - 239-253
LID - 10.3390/arm91030019 [doi]
AB  - BACKGROUND: Exercise-induced bronchoconstriction (EIB) is a common problem in 
      elite athletes. Classical pathways in the development of EIB include the osmotic 
      and thermal theory as well as the presence of epithelial injury in the airway, 
      with local water loss being the main trigger of EIB. This study aimed to 
      investigate the effects of systemic hydration on pulmonary function and to 
      establish whether it can reverse dehydration-induced alterations in pulmonary 
      function. MATERIALS AND METHODS: This follow-up study was performed among 
      professional cyclists, without a history of asthma and/or atopy. Anthropometric 
      characteristics were recorded for all participants, and the training age was 
      determined. In addition, pulmonary function tests and specific markers such as 
      fractional exhaled nitric oxide (FeNO) and immunoglobulin E (IgE) were measured. 
      All the athletes underwent body composition analysis and cardiopulmonary exercise 
      testing (CPET). After CPET, spirometry was followed at the 3rd, 5th, 10th, 15th, 
      and 30th min. This study was divided into two phases: before and after hydration. 
      Cyclists, who experienced a decrease in Forced Expiratory Volume in one second 
      (FEV(1)) >/= 10% and/or Maximal Mild-Expiratory Flow Rate (MEF(25-75)) >/= 20% after 
      CPET in relation to the results of the spirometry before CPET, repeated the test 
      in 15-20 days, following instructions for hydration. RESULTS: One hundred male 
      cyclists (n = 100) participated in Phase A. After exercise, there was a decrease 
      in all spirometric parameters (p < 0.001). In Phase B, after hydration, in all 
      comparisons, the changes in spirometric values were significantly lower than 
      those in Phase A (p < 0.001). CONCLUSIONS: The findings of this study suggest 
      that professional cyclists have non-beneficial effects on respiratory function. 
      Additionally, we found that systemic hydration has a positive effect on 
      spirometry in cyclists. Of particular interest are small airways, which appear to 
      be affected independently or in combination with the decrease in FEV(1). Our data 
      suggest that pulmonary function improves systemic after hydration.
FAU - Pigakis, Konstantinos M
AU  - Pigakis KM
AUID- ORCID: 0000-0001-9131-2939
AD  - Department of Respiratory & Critical Care Medicine, Creta Interclinic, 71304 
      Heraklion, Greece.
FAU - Stavrou, Vasileios T
AU  - Stavrou VT
AUID- ORCID: 0000-0002-2437-5339
AD  - Laboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Department of 
      Respiratory Medicine, Faculty of Medicine, University of Thessaly, 41110 Larissa, 
      Greece.
FAU - Pantazopoulos, Ioannis
AU  - Pantazopoulos I
AUID- ORCID: 0000-0002-8846-519X
AD  - Emergency Medicine, Faculty of Medicine, University of Thessaly, 41110 Larissa, 
      Greece.
FAU - Daniil, Zoe
AU  - Daniil Z
AD  - Laboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Department of 
      Respiratory Medicine, Faculty of Medicine, University of Thessaly, 41110 Larissa, 
      Greece.
FAU - Kontopodi-Pigaki, Aggeliki K
AU  - Kontopodi-Pigaki AK
AD  - Department of Respiratory & Critical Care Medicine, Creta Interclinic, 71304 
      Heraklion, Greece.
FAU - Gourgoulianis, Konstantinos
AU  - Gourgoulianis K
AUID- ORCID: 0000-0001-9541-1010
AD  - Laboratory of Cardiopulmonary Testing and Pulmonary Rehabilitation, Department of 
      Respiratory Medicine, Faculty of Medicine, University of Thessaly, 41110 Larissa, 
      Greece.
LA  - eng
PT  - Journal Article
DEP - 20230607
PL  - Switzerland
TA  - Adv Respir Med
JT  - Advances in respiratory medicine
JID - 101697329
SB  - IM
MH  - Humans
MH  - Male
MH  - Bronchoconstriction
MH  - *Asthma, Exercise-Induced
MH  - Follow-Up Studies
MH  - Lung
MH  - *Asthma/metabolism
PMC - PMC10295158
OTO - NOTNLM
OT  - elite athletes
OT  - exercise-induced airway injury
OT  - exercise-induced bronchoconstriction
OT  - exercise-induced dehydration
OT  - hydration
OT  - pulmonary function tests
COIS- The authors declare no conflict of interest.
EDAT- 2023/06/27 13:11
MHDA- 2023/06/29 06:42
PMCR- 2023/06/07
CRDT- 2023/06/27 09:34
PHST- 2023/05/06 00:00 [received]
PHST- 2023/05/30 00:00 [revised]
PHST- 2023/05/31 00:00 [accepted]
PHST- 2023/06/29 06:42 [medline]
PHST- 2023/06/27 13:11 [pubmed]
PHST- 2023/06/27 09:34 [entrez]
PHST- 2023/06/07 00:00 [pmc-release]
AID - arm91030019 [pii]
AID - arm-91-00019 [pii]
AID - 10.3390/arm91030019 [doi]
PST - epublish
SO  - Adv Respir Med. 2023 Jun 7;91(3):239-253. doi: 10.3390/arm91030019.